Q9YEZ1 (RPOL_AERPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit L
EC=2.7.7.6

Gene names

Name:	rpoL
Ordered Locus Names:	APE_0443.1

Organism

Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP]

Taxonomic identifier

272557 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum › Aeropyrum pernix

Protein attributes

Sequence length	99 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_00261
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00261
Sequence similarities	Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 99	99	DNA-directed RNA polymerase subunit L HAMAP-Rule MF_00261		PRO_0000149321

Sequences

	Sequence		Length	Mass (Da)
	Q9YEZ1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 87145BFDB92AB175	FASTA	99	11,547
	10 20 30 40 50 60 MERLRIIRES RGSYVIQVYG EDHTLGTLLV EAIKRVSNPK LAYYEAVHPM EDIIQVYVKY 70 80 90 EDDVDIKEVL RKASDYLLEV IGDFRRRYLE ALERRGGGG

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000002 Genomic DNA. Translation: BAA79405.2.
PIR	A72739.
RefSeq	NP_147236.2. NC_000854.2.
3D structure databases
ProteinModelPortal	Q9YEZ1.
ModBase	Search...
Protein-protein interaction databases
STRING	272557.APE_0443.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA79405; BAA79405; APE_0443.1.
GeneID	1444631.
KEGG	ape:APE_0443.1.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1761.
HOGENOM	HOG000179862.
KO	K03056.
ProtClustDB	CLSK2782464.
Enzyme and pathway databases
BioCyc	APER272557:GJD6-334-MONOMER.
Family and domain databases
HAMAP	MF_00261. RNApol_arch_L.
InterPro	IPR009025. DNA-dir_RNA_pol_RBP11-like. IPR008193. RNA_pol_Rpb11_13-16kDa_CS. IPR022905. RNAP_L. [Graphical view]
SUPFAM	SSF55257. RNAP_RBP11-like. 1 hit.
PROSITE	PS01154. RNA_POL_L_13KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOL_AERPE

Accession

Primary (citable) accession number: Q9YEZ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	June 26, 2007
Last modified:	May 1, 2013
This is version 74 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program