Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9YEK9 (AROA_AERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase

EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:APE_0569
OrganismAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP]
Taxonomic identifier272557 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000088325

Sequences

Sequence LengthMass (Da)Tools
Q9YEK9 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 49F77CE881F681A6

FASTA42744,971
        10         20         30         40         50         60 
MVWLRAPDRV VVHPSTVEGR VEAPPSKSYT HRMLFLALLA RGRSVVRRPL VSNDTLATLN 

        70         80         90        100        110        120 
AVALLGGKPR LGRGVAEVEG GEVRGGAVVY AAGSGTTIRI AMGVAAHSAE ATLLYGDESL 

       130        140        150        160        170        180 
NRRPVHPLSE ALRSMGARVC DTGGNPPVKV SGPLRRASVE VDAAISSQFA TSLLIAGSRL 

       190        200        210        220        230        240 
GEFELSAARL SSRGYVDITL ESLSMFGVRV EREGYRLFRL RGTPKPVDAA VPGDYSSASF 

       250        260        270        280        290        300 
MLAAGAIAGR VEVEGLRPVD PQPDRRIVEL LRSMGARVRV EGGVVAVEST GPLEPVDVDL 

       310        320        330        340        350        360 
DGSPDLAPVA AVLAAYARGV SRLRGLERLK YKESDRLSAI AWNLARLGVE ARVRGGILEI 

       370        380        390        400        410        420 
RGGGVEGGVA RSWGDHRIAM AMAVAGLGAR RPVAVEGFSR VPDSYPGFLE DLARLGARVE 


AVKGGGV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000002 Genomic DNA. Translation: BAA79537.1.
PIRA72642.
RefSeqNP_147332.1. NC_000854.2.

3D structure databases

ProteinModelPortalQ9YEK9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1444731.
GenomeReviewsGene locus APE_0569 in contig BA000002_GR.
KEGGape:APE_0569.
NMPDRfig|272557.1.peg.440.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMARLRIKEC.
PhylomeDBQ9YEK9.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycAPER272557:APE0569-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_AERPE
AccessionPrimary (citable) accession number: Q9YEK9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: December 14, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families