Reviewed, UniProtKB/Swiss-Prot Q9YDM7 (MPGP_AERPE)

Names and origin

Protein names

Recommended name:
    Mannosyl-3-phosphoglycerate phosphatase
      Short name=MPGP
    EC=3.1.3.70

Gene names

Name:	mngB
Ordered Locus Names:	APE_0887.1

Organism

Aeropyrum pernix [Complete proteome] [HAMAP]

Taxonomic identifier

56636 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) By similarity.
Catalytic activity	2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. HAMAP MF_00617
Pathway	Carbohydrate biosynthesis; mannosylglycerate biosynthesis; 2(alpha-D-mannosyl)-D-glycerate from GDP-D-mannose (MPG route): step 2/2. HAMAP MF_00617
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the HAD-like hydrolase superfamily. MPGP family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mannosylglycerate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	mannosyl-3-phosphoglycerate phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Mannosyl-3-phosphoglycerate phosphatase HAMAP MF_00617		PRO_0000184970

Sequences

	Sequence		Length	Mass (Da)
	Q9YDM7-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 1A817EEAFB559F74	FASTA	277	30,128
	10 20 30 40 50 60 MEARPCSGVI FTDLDNTLVG PGGEAGEAGE VYLEALDLGY RVVPVTSKSI YEIVELWDSI 70 80 90 100 110 120 GVPPGERIAL AESGGAIYGP RGSLARPTGF NSEVGLEYTA LGKPLASIDA LLDSLAETCG 130 140 150 160 170 180 AVRLSKADAT EAQLITGLPR ERAALAARRE YLEVIWSRSQ ECLDTILSTA LRYRELTYVH 190 200 210 220 230 240 RAPRTVQIAA HRGKGMAIDA ALQEPLLRPC AKVVVTAGDS SHDIPIIERG MLAFRVDYNR 250 260 270 DWSRLVKPIY MVIPYEAPKA WTMLIETVKT RSNTPSL

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed: 10382966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000002 Genomic DNA. Translation: BAA79870.2.
PIR	F72683.
RefSeq	NP_147576.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1444980.
GenomeReviews	Gene locus APE_0887.1 in contig BA000002_GR.
KEGG	ape:APE_0887.1.
NMPDR	fig|272557.1.peg.684.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9YDM7.
Enzyme and pathway databases
BRENDA	3.1.3.70. 256344.
Family and domain databases
HAMAP	MF_00617. [Tree]
InterPro	IPR006379. HAD-SF_hydro_IIB. IPR006381. HAD-SF_hydro_IIB_YedP. IPR012813. Osmo_MPG_phos. [Graphical view]
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01486. HAD-SF-IIB-MPGP. 1 hit. TIGR02461. osmo_MPG_phos. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGP_AERPE

Accession

Primary (citable) accession number: Q9YDM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	June 26, 2007
Last modified:	June 16, 2009
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)