Reviewed, UniProtKB/Swiss-Prot Q9YDM5 (MPGS_AERPE)

Names and origin

Protein names

Recommended name:
    Mannosyl-3-phosphoglycerate synthase
      Short name=MPG synthase
      Short name=MPGS
    EC=2.4.1.217

Gene names

Name:	mngA
Ordered Locus Names:	APE_0889.1

Organism

Aeropyrum pernix [Complete proteome] [HAMAP]

Taxonomic identifier

56636 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG) By similarity.
Catalytic activity	GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate.
Pathway	Carbohydrate biosynthesis; mannosylglycerate biosynthesis; 2(alpha-D-mannosyl)-D-glycerate from GDP-D-mannose (MPG route): step 1/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glycosyltransferase 2 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mannosylglycerate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	mannosyl-3-phosphoglycerate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 388	388	Mannosyl-3-phosphoglycerate synthase		PRO_0000059284

Sequences

	Sequence		Length	Mass (Da)
	Q9YDM5-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 3ADC825CEB58DF05	FASTA	388	42,812
	10 20 30 40 50 60 MMLSLPAKFE VFGAVRIYDV SRVLSLDGRP KSRPTNLVYV DRGELEDAAF RTVIVVPVKD 70 80 90 100 110 120 EDLLTLENVL RSIPTESPVV VVSASTREPV DRFSNEVELA RLISRSLQRD IAIVYQFDPA 130 140 150 160 170 180 WSEALSGTPL ESMVGASGRV RKGKGEGMLL GFIVAAALGA DFVGYVDSDN YVPGSALEYS 190 200 210 220 230 240 WIYYSALSRA TSSYSMVRIV WPYKGKLAAS DMYLRKRGRV STITNGVLNY TLSIYKRIET 250 260 270 280 290 300 DIIKTGNSGE QALTVKLGME MNWGSGFAVE TYQLVWMLEN CYLGLQAGKC PIAPDYIEVR 310 320 330 340 350 360 QVSPLNPHIH AERGDEHIAE MTAVSLGTIF HSSLASEEVK SRILDQLKSL GLAEEPPKPS 370 380 TYRPAGTDPK KVFASFIAES SDSYYFAV

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed: 10382966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000002 Genomic DNA. Translation: BAA79872.2.
PIR	H72683.
RefSeq	NP_147578.2.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT55. Glycosyltransferase Family 55.
Genome annotation databases
GeneID	1444982.
GenomeReviews	Gene locus APE_0889.1 in contig BA000002_GR.
KEGG	ape:APE_0889.1.
NMPDR	fig|272557.1.peg.686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q9YDM5.
Enzyme and pathway databases
BRENDA	2.4.1.217. 256344.
Family and domain databases
InterPro	IPR012812. Osmo_MPG_synth. [Graphical view]
Pfam	PF09488. Osmo_MPGsynth. 1 hit. [Graphical view]
TIGRFAMs	TIGR02460. osmo_MPGsynth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGS_AERPE

Accession

Primary (citable) accession number: Q9YDM5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	June 26, 2007
Last modified:	June 16, 2009
This is version 41 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)