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Protein

Riboflavin synthase

Gene

ribC

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine.

Pathwayi

GO - Molecular functioni

  1. riboflavin synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. riboflavin biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Riboflavin biosynthesis

Enzyme and pathway databases

BioCyciAPER272557:GJD6-721-MONOMER.
UniPathwayiUPA00275; UER00405.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin synthase (EC:2.5.1.9)
Gene namesi
Name:ribC
Ordered Locus Names:APE_0988
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
ProteomesiUP000002518: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. riboflavin synthase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 155155Riboflavin synthasePRO_0000134858Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272557.APE_0988.

Structurei

3D structure databases

ProteinModelPortaliQ9YDC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DMRL synthase family.Curated

Phylogenomic databases

eggNOGiCOG1731.
HOGENOMiHOG000227234.
KOiK00793.
OMAiGIVDTTF.

Family and domain databases

Gene3Di3.40.50.960. 1 hit.
InterProiIPR002180. DMRL_synthase.
IPR006399. Ribfl_synth_arc.
[Graphical view]
PfamiPF00885. DMRL_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF015750. Ribfl_synth_arc. 1 hit.
SUPFAMiSSF52121. SSF52121. 1 hit.
TIGRFAMsiTIGR01506. ribC_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YDC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKCVGVADT TFARVDMGSV AEEVLRRRLP GYRIVRHTVP GIKDLPGAAK
60 70 80 90 100
RILSMGCEGV ITLGWVGRRE ADKLSYLAAS VGLIMVEVLT GKIVIDVTVH
110 120 130 140 150
EDEAEAPEEL AAIAVDRARK HAENLAALIR EGPEALVKHA GMGLRQGYPD

AGPIK
Length:155
Mass (Da):16,576
Last modified:November 1, 1999 - v1
Checksum:i644B7A1BD313A4F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA79972.1.
PIRiD72696.
RefSeqiNP_147650.1. NC_000854.2.
WP_010866118.1. NC_000854.2.

Genome annotation databases

EnsemblBacteriaiBAA79972; BAA79972; APE_0988.
GeneIDi1445055.
KEGGiape:APE_0988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA79972.1.
PIRiD72696.
RefSeqiNP_147650.1. NC_000854.2.
WP_010866118.1. NC_000854.2.

3D structure databases

ProteinModelPortaliQ9YDC5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272557.APE_0988.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA79972; BAA79972; APE_0988.
GeneIDi1445055.
KEGGiape:APE_0988.

Phylogenomic databases

eggNOGiCOG1731.
HOGENOMiHOG000227234.
KOiK00793.
OMAiGIVDTTF.

Enzyme and pathway databases

UniPathwayiUPA00275; UER00405.
BioCyciAPER272557:GJD6-721-MONOMER.

Family and domain databases

Gene3Di3.40.50.960. 1 hit.
InterProiIPR002180. DMRL_synthase.
IPR006399. Ribfl_synth_arc.
[Graphical view]
PfamiPF00885. DMRL_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF015750. Ribfl_synth_arc. 1 hit.
SUPFAMiSSF52121. SSF52121. 1 hit.
TIGRFAMsiTIGR01506. ribC_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiRISC_AERPE
AccessioniPrimary (citable) accession number: Q9YDC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: March 4, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.