Q9YDC5 (RISC_AERPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Riboflavin synthase
EC=2.5.1.9

Gene names

Name:	ribC
Ordered Locus Names:	APE_0988

Organism

Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP]

Taxonomic identifier

272557 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum › Aeropyrum pernix

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine.
Pathway	Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.
Sequence similarities	Belongs to the DMRL synthase family.

Ontologies

Keywords
Biological process	Riboflavin biosynthesis
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	riboflavin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	riboflavin synthase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	riboflavin synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 155	155	Riboflavin synthase		PRO_0000134858

Sequences

	Sequence		Length	Mass (Da)
	Q9YDC5 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 644B7A1BD313A4F3	FASTA	155	16,576
	10 20 30 40 50 60 MGKCVGVADT TFARVDMGSV AEEVLRRRLP GYRIVRHTVP GIKDLPGAAK RILSMGCEGV 70 80 90 100 110 120 ITLGWVGRRE ADKLSYLAAS VGLIMVEVLT GKIVIDVTVH EDEAEAPEEL AAIAVDRARK 130 140 150 HAENLAALIR EGPEALVKHA GMGLRQGYPD AGPIK

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000002 Genomic DNA. Translation: BAA79972.1.
PIR	D72696.
RefSeq	NP_147650.1. NC_000854.2.
3D structure databases
ProteinModelPortal	Q9YDC5.
ModBase	Search...
Protein-protein interaction databases
STRING	272557.APE_0988.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA79972; BAA79972; APE_0988.
GeneID	1445055.
KEGG	ape:APE_0988.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1731.
HOGENOM	HOG000227234.
KO	K00793.
OMA	IVDTTFA.
ProtClustDB	PRK06455.
Enzyme and pathway databases
BioCyc	APER272557:GJD6-721-MONOMER.
UniPathway	UPA00275; UER00405.
Family and domain databases
Gene3D	3.40.50.960. 1 hit.
InterPro	IPR002180. DMRL_synthase. IPR006399. Ribfl_synth_arc. [Graphical view]
Pfam	PF00885. DMRL_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF015750. Ribfl_synth_arc. 1 hit.
SUPFAM	SSF52121. DMRL_synthase. 1 hit.
TIGRFAMs	TIGR01506. ribC_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RISC_AERPE

Accession

Primary (citable) accession number: Q9YDC5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1999
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program