Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9YD40 (Q9YD40_AERPE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit alpha RuleBase RU000699

EC=6.2.1.5 RuleBase RU000699
Gene names
Name:sucD EMBL BAA80057.2
Ordered Locus Names:APE_1072.1 EMBL BAA80057.2
OrganismAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP] EMBL BAA80057.2
Taxonomic identifier272557 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase alpha subunit family. RuleBase RU000677

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2491Tele-phosphohistidine intermediate By similarity PIRSR PIRSR001553-1

Sequences

Sequence LengthMass (Da)Tools
Q9YD40 [UniParc].

Last modified November 14, 2006. Version 2.
Checksum: C6D0BFC049CE1F75

FASTA29230,897
        10         20         30         40         50         60 
MAVLVDSETR VLVQGITGRE GSFHAKAMLE YGTKVVAGVT PGKGGSEVHG VPVYDSVKEA 

        70         80         90        100        110        120 
LAEHPEINTS IVFVPAPFAP DAVYEAVDAG IRLVVVITEG IPVHDTMRFV NYARQKGATI 

       130        140        150        160        170        180 
IGPNCPGAIT PGQAKVGIMP GHIFKEGGVA VVSRSGTLTY EISYMLTRQG IGQSTVIGIG 

       190        200        210        220        230        240 
GDPIVGLSFT EALKLFQEDP QTEALVLIGE IGGDMEERAA EMIKKGEFTK PVIAYIAGRT 

       250        260        270        280        290 
APPEKRMGHA GAIIMMGTGT YEGKVKALRE AGVEVAETPF EVPELVRKAL RR 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1."
Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. expand/collapse author list , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.
DNA Res. 6:83-101(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.
[2]"Crystal Structure of Succinyl-CoA Synthetase Alpha Chain from Aeropyrum pernix K1."
Niwa H., Kuramitsu S., Yokoyama S.
Submitted (APR-2007) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000002 Genomic DNA. Translation: BAA80057.2.
PIRA72707.
RefSeqNP_147697.2. NC_000854.2.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2YV2X-ray2.20A1-292[»]
ProteinModelPortalQ9YD40.
SMRQ9YD40. Positions 4-290.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272557.APE_1072.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA80057; BAA80057; APE_1072.1.
GeneID1445101.
KEGGape:APE_1072.1.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0074.
HOGENOMHOG000239685.
KOK01902.
OMAFEQDPQT.

Enzyme and pathway databases

BioCycAPER272557:GJD6-760-MONOMER.

Family and domain databases

Gene3D3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001553. SucCS_alpha. 1 hit.
PRINTSPR01798. SCOASYNTHASE.
SMARTSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMSSF52210. SSF52210. 1 hit.
TIGRFAMsTIGR01019. sucCoAalpha. 1 hit.
PROSITEPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9YD40.

Entry information

Entry nameQ9YD40_AERPE
AccessionPrimary (citable) accession number: Q9YD40
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 14, 2006
Last modified: June 11, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)