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Q9YD20

- RNP4_AERPE

UniProt

Q9YD20 - RNP4_AERPE

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Protein

Ribonuclease P protein component 4

Gene
rnp4, APE_1092.1
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi66 – 661Zinc By similarity
Metal bindingi69 – 691Zinc By similarity
Metal bindingi96 – 961Zinc By similarity
Metal bindingi99 – 991Zinc By similarity

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciAPER272557:GJD6-773-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 4 (EC:3.1.26.5)
Short name:
RNase P component 4
Alternative name(s):
Rpp21
Gene namesi
Name:rnp4
Ordered Locus Names:APE_1092.1
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
ProteomesiUP000002518: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Ribonuclease P protein component 4UniRule annotationPRO_0000153848Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits Reviewed prediction.

Protein-protein interaction databases

STRINGi272557.APE_1092.1.

Structurei

3D structure databases

ProteinModelPortaliQ9YD20.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2023.
KOiK03540.

Family and domain databases

HAMAPiMF_00757. RNase_P_4.
InterProiIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9YD20-1 [UniParc]FASTAAdd to Basket

« Hide

MKSRRSRCRR SFTTLVRREE ERLARWALEL ARRGLTGEAR RVAEQLFQLA    50
ASTRVRPPRR VKRLFCKNCR TPLIPGLTAR VRLRSQGGMS YTVVTCLSCG 100
WIHRYPYRKG PRGGAPISPP AAEYGSGGRD SGEREDKGPQ GPPRQGGRDN 150
RQGGGHQGGP KGD 163
Length:163
Mass (Da):18,167
Last modified:June 26, 2007 - v2
Checksum:iFA24D0F183ABB5EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000002 Genomic DNA. Translation: BAA80077.2.
PIRiE72709.
RefSeqiNP_147712.2. NC_000854.2.
WP_010866169.1. NC_000854.2.

Genome annotation databases

EnsemblBacteriaiBAA80077; BAA80077; APE_1092.1.
GeneIDi1445786.
KEGGiape:APE_1092.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000002 Genomic DNA. Translation: BAA80077.2 .
PIRi E72709.
RefSeqi NP_147712.2. NC_000854.2.
WP_010866169.1. NC_000854.2.

3D structure databases

ProteinModelPortali Q9YD20.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272557.APE_1092.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA80077 ; BAA80077 ; APE_1092.1 .
GeneIDi 1445786.
KEGGi ape:APE_1092.1.

Phylogenomic databases

eggNOGi COG2023.
KOi K03540.

Enzyme and pathway databases

BioCyci APER272557:GJD6-773-MONOMER.

Family and domain databases

HAMAPi MF_00757. RNase_P_4.
InterProi IPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiRNP4_AERPE
AccessioniPrimary (citable) accession number: Q9YD20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: June 26, 2007
Last modified: September 3, 2014
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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