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Q9YD20

- RNP4_AERPE

UniProt

Q9YD20 - RNP4_AERPE

Protein

Ribonuclease P protein component 4

Gene

rnp4

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 2 (26 Jun 2007)
      Previous versions | rss
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    Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi66 – 661ZincUniRule annotation
    Metal bindingi69 – 691ZincUniRule annotation
    Metal bindingi96 – 961ZincUniRule annotation
    Metal bindingi99 – 991ZincUniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciAPER272557:GJD6-773-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 4UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 4UniRule annotation
    Alternative name(s):
    Rpp21UniRule annotation
    Gene namesi
    Name:rnp4UniRule annotation
    Ordered Locus Names:APE_1092.1
    OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
    Taxonomic identifieri272557 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
    ProteomesiUP000002518: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 163163Ribonuclease P protein component 4PRO_0000153848Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi272557.APE_1092.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9YD20.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 4 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2023.
    KOiK03540.

    Family and domain databases

    HAMAPiMF_00757. RNase_P_4.
    InterProiIPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view]
    PANTHERiPTHR14742. PTHR14742. 1 hit.
    PfamiPF04032. Rpr2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9YD20-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKSRRSRCRR SFTTLVRREE ERLARWALEL ARRGLTGEAR RVAEQLFQLA    50
    ASTRVRPPRR VKRLFCKNCR TPLIPGLTAR VRLRSQGGMS YTVVTCLSCG 100
    WIHRYPYRKG PRGGAPISPP AAEYGSGGRD SGEREDKGPQ GPPRQGGRDN 150
    RQGGGHQGGP KGD 163
    Length:163
    Mass (Da):18,167
    Last modified:June 26, 2007 - v2
    Checksum:iFA24D0F183ABB5EA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000002 Genomic DNA. Translation: BAA80077.2.
    PIRiE72709.
    RefSeqiNP_147712.2. NC_000854.2.
    WP_010866169.1. NC_000854.2.

    Genome annotation databases

    EnsemblBacteriaiBAA80077; BAA80077; APE_1092.1.
    GeneIDi1445786.
    KEGGiape:APE_1092.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000002 Genomic DNA. Translation: BAA80077.2 .
    PIRi E72709.
    RefSeqi NP_147712.2. NC_000854.2.
    WP_010866169.1. NC_000854.2.

    3D structure databases

    ProteinModelPortali Q9YD20.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272557.APE_1092.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA80077 ; BAA80077 ; APE_1092.1 .
    GeneIDi 1445786.
    KEGGi ape:APE_1092.1.

    Phylogenomic databases

    eggNOGi COG2023.
    KOi K03540.

    Enzyme and pathway databases

    BioCyci APER272557:GJD6-773-MONOMER.

    Family and domain databases

    HAMAPi MF_00757. RNase_P_4.
    InterProi IPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view ]
    PANTHERi PTHR14742. PTHR14742. 1 hit.
    Pfami PF04032. Rpr2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

    Entry informationi

    Entry nameiRNP4_AERPE
    AccessioniPrimary (citable) accession number: Q9YD20
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2004
    Last sequence update: June 26, 2007
    Last modified: October 1, 2014
    This is version 59 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3