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Protein
Submitted name:

Repair endonuclease XPF

Gene

APE_1436.1

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi46MagnesiumCombined sources1
Metal bindingi56MagnesiumCombined sources1
Metal bindingi57Magnesium; via carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseImported, Hydrolase, Nuclease

Keywords - Ligandi

MagnesiumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BRENDAi3.1.99.B2. 171.

Names & Taxonomyi

Protein namesi
Submitted name:
Repair endonuclease XPFImported
Gene namesi
Ordered Locus Names:APE_1436.1Imported
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)Imported
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272557.APE_1436.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BGWX-ray2.80A/B12-223[»]
2BHNX-ray3.20A/B/C/D12-225[»]
ProteinModelPortaliQ9YC15.
SMRiQ9YC15.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9YC15.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 94ERCC4InterPro annotationAdd BLAST81
Domaini166 – 185HhH1InterPro annotationAdd BLAST20
Domaini198 – 217HhH1InterPro annotationAdd BLAST20

Phylogenomic databases

eggNOGiarCOG04206. Archaea.
COG1948. LUCA.
HOGENOMiHOG000104951.
KOiK10848.
OMAiYTEDKAQ.

Family and domain databases

Gene3Di3.40.50.10130. 1 hit.
InterProiIPR020819. DNA_repair_nuc_XPF/helicase.
IPR006166. ERCC4_domain.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR011335. Restrct_endonuc-II-like.
IPR010994. RuvA_2-like.
[Graphical view]
PfamiPF02732. ERCC4. 1 hit.
[Graphical view]
SMARTiSM00891. ERCC4. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF47781. SSF47781. 1 hit.
SSF52980. SSF52980. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YC15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGGRYRRGG FRPRVYVDVR EERSPVPSIL ESLGVQVIPK QLPMGDYLVS
60 70 80 90 100
DSIIVERKTS SDFAKSLFDG RLFEQASRLA EHYETVFIIV EGPPVPRRYR
110 120 130 140 150
GRERSLYAAM AALQLDYGIR LMNTMDPKGT ALVIESLARL STREGGQRIV
160 170 180 190 200
IHKKPRLSDV REWQLYILQS FPGIGRRTAE RILERFGSLE RFFTASKAEI
210 220 230 240
SKVEGIGEKR AEEIKKILMT PYKRSTGGGR RHASLDDFYR GEGEAGSG
Length:248
Mass (Da):28,114
Last modified:November 14, 2006 - v2
Checksum:i4BDF9DD52DBA6AD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80433.2.
PIRiC72622.

Genome annotation databases

EnsemblBacteriaiBAA80433; BAA80433; APE_1436.1.
KEGGiape:APE_1436.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80433.2.
PIRiC72622.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BGWX-ray2.80A/B12-223[»]
2BHNX-ray3.20A/B/C/D12-225[»]
ProteinModelPortaliQ9YC15.
SMRiQ9YC15.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272557.APE_1436.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA80433; BAA80433; APE_1436.1.
KEGGiape:APE_1436.1.

Phylogenomic databases

eggNOGiarCOG04206. Archaea.
COG1948. LUCA.
HOGENOMiHOG000104951.
KOiK10848.
OMAiYTEDKAQ.

Enzyme and pathway databases

BRENDAi3.1.99.B2. 171.

Miscellaneous databases

EvolutionaryTraceiQ9YC15.

Family and domain databases

Gene3Di3.40.50.10130. 1 hit.
InterProiIPR020819. DNA_repair_nuc_XPF/helicase.
IPR006166. ERCC4_domain.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR011335. Restrct_endonuc-II-like.
IPR010994. RuvA_2-like.
[Graphical view]
PfamiPF02732. ERCC4. 1 hit.
[Graphical view]
SMARTiSM00891. ERCC4. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF47781. SSF47781. 1 hit.
SSF52980. SSF52980. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9YC15_AERPE
AccessioniPrimary (citable) accession number: Q9YC15
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 14, 2006
Last modified: November 2, 2016
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.