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Protein

Replication factor C small subunit

Gene

rfcS

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi47 – 548ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1031-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Replication factor C small subunitUniRule annotation
Short name:
RFC small subunitUniRule annotation
Alternative name(s):
Clamp loader small subunitUniRule annotation
Gene namesi
Name:rfcSUniRule annotation
Ordered Locus Names:APE_1522.1
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 325325Replication factor C small subunitPRO_0000135970Add
BLAST

Interactioni

Subunit structurei

Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).UniRule annotation

Protein-protein interaction databases

STRINGi272557.APE_1522.1.

Structurei

3D structure databases

ProteinModelPortaliQ9YBS7.
SMRiQ9YBS7. Positions 4-322.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the activator 1 small subunits family. RfcS subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00469. Archaea.
COG0470. LUCA.
HOGENOMiHOG000224154.
KOiK04801.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01509. RfcS. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR023748. Rep_factor-C_ssu_arc.
IPR013748. Rep_factorC_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YBS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVLEMLWV EKYRPRSLDD IVDQKHVVER LKQFVKQRNM PHLLFAGPPG
60 70 80 90 100
TGKTTAAHAL AHDLFGENYR QYMLELNASD ERGINVIREK VKEFARSRTP
110 120 130 140 150
PEIPFKIVLL DEADNMTSDA QQALRRLMEL YSSVTRFILI ANYPSKIIDP
160 170 180 190 200
IQSRCAFFRF QPLSKQDVIE RLRYIAENEG VDYEEEALDA IYEISEGDMR
210 220 230 240 250
KAINVLQAAS YLGKVTVDAV YRVVGMAKPR EVREMLATAL KGDFTAARSL
260 270 280 290 300
LRKIMIEYGM SGEDVARQIH RELFSTELKM PEELRVLAAD YLGEVHYRLV
310 320
EGSDDDIQLS AFLAWLTMMS RKLEV
Length:325
Mass (Da):37,344
Last modified:June 26, 2007 - v3
Checksum:iA9C667A1B7AB9A9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80521.2.
PIRiC72633.

Genome annotation databases

EnsemblBacteriaiBAA80521; BAA80521; APE_1522.1.
KEGGiape:APE_1522.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80521.2.
PIRiC72633.

3D structure databases

ProteinModelPortaliQ9YBS7.
SMRiQ9YBS7. Positions 4-322.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272557.APE_1522.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA80521; BAA80521; APE_1522.1.
KEGGiape:APE_1522.1.

Phylogenomic databases

eggNOGiarCOG00469. Archaea.
COG0470. LUCA.
HOGENOMiHOG000224154.
KOiK04801.

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1031-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01509. RfcS. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR027417. P-loop_NTPase.
IPR023748. Rep_factor-C_ssu_arc.
IPR013748. Rep_factorC_C.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF08542. Rep_fac_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRFCS_AERPE
AccessioniPrimary (citable) accession number: Q9YBS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: June 26, 2007
Last modified: May 11, 2016
This is version 81 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.