Reviewed, UniProtKB/Swiss-Prot Q9YBK7 (ACYP_AERPE)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	APE_1591.1

Organism

Aeropyrum pernix [Complete proteome] [HAMAP]

Taxonomic identifier

56636 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Acylphosphatase HAMAP MF_01450		PRO_0000326855
Regions
	Domain	13 – 101	89	Acylphosphatase-like
Sites
	Active site	28	1	By similarity
	Active site	46	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9YBK7-1 [UniParc]. Last modified November 14, 2006. Version 2. Checksum: B689986CE88B27E3	FASTA	101	11,443
	10 20 30 40 50 60 MEGVPSVRDS LVRARILVRG VVQGVFFRAS MREEALRLGL SGWVRNLPDG ESVEAVVEGR 70 80 90 100 GDAVERIICW CLRGPPAARV RELRVELEPY KGEFRGFEIR Y

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed: 10382966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000002 Genomic DNA. Translation: BAA80591.2.
PIR	B72538.
RefSeq	NP_148044.2.
3D structure databases
HSSP	HSSP built from PDB template 1W2I based on UniProtKB P84142.
SMR	Q9YBK7. Positions 11-101.
ModBase	Search...
Genome annotation databases
GeneID	1446117.
GenomeReviews	Gene locus APE_1591.1 in contig BA000002_GR.
KEGG	ape:APE_1591.1.
NMPDR	fig|272557.1.peg.1152.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG750266.
OMA	WFRASAK.
Enzyme and pathway databases
BioCyc	APER272557:APE1591-MONOMER.
BRENDA	3.6.1.7. 256344.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_AERPE

Accession

Primary (citable) accession number: Q9YBK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	November 14, 2006
Last modified:	January 19, 2010
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)