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Reviewed, UniProtKB/Swiss-Prot Q9YBA2 (GCST_AERPE)

Last modified February 9, 2010. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable aminomethyltransferase
    EC=2.1.2.10
Alternative name(s):
    Glycine cleavage system T protein
Gene names
Name: gcvT
Ordered Locus Names: APE_1695.1
OrganismAeropyrum pernix [Complete proteome] [HAMAP]
Taxonomic identifier56636 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259

Sequence similarities

Belongs to the gcvT family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 375375Probable aminomethyltransferase HAMAP MF_00259
PRO_0000122620

Sequences

Sequence LengthMass (Da)Tools
Q9YBA2-1 [UniParc].

Last modified December 1, 2000. Version 2.
Checksum: A1F809E5FA785EA9

FASTA37541,261
        10         20         30         40         50         60 
MPVRRHILED LHRSLGATFG EFAGWSVPMS YEGTLKEHMA VRREAGIFDI SHMGRMIVSG 

        70         80         90        100        110        120 
EGATELLERI YTKRVSKTKV GFMSGPTLAL NEYARVKDDE MPYRLGEEEW LIVPNAAVAD 

       130        140        150        160        170        180 
AMLEYFSSIA SSMGLNVSIR DLRERYALLA LQGPGAARVM EEMGGGDLLD LKPLQFRENA 

       190        200        210        220        230        240 
GIAGVTAYIV SRSGWTGEDG FEIIAEVEAA KRIFKAAVEA GAKPAGIAAR DTLRIEAGFV 

       250        260        270        280        290        300 
LGGHEYGEDP LRWPCAVSLR YGLGAIDWGK KGFVGEAALR ACRREGVRWI RVGLVMKKKY 

       310        320        330        340        350        360 
ARMIPRSGYR LYVDDVDVGW VTSGTFSPVI GRGVAQAYID SRYAYIGDTI EVDVRGKRGE 

       370 
ARLQEFPLVP LGSRG 

« Hide

References

[1]"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1."
Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. expand/collapse author list , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.
DNA Res. 6:83-101(1999) [PubMed: 10382966] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000002 Genomic DNA. Translation: BAA80696.2.
PIRC72551.
RefSeqNP_148104.2.

3D structure databases

SMRQ9YBA2. Positions 3-368.
ModBaseSearch...

Genome annotation databases

GeneID1446178.
GenomeReviewsGene locus APE_1695.1 in contig BA000002_GR.
KEGGape:APE_1695.1.
NMPDRfig|272557.1.peg.1212.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG299834.
OMAHAREASW.

Enzyme and pathway databases

BioCycAPER272557:APE1695-MONOMER.
BRENDA2.1.2.10. 256344.

Family and domain databases

HAMAPMF_00259. GcvT.
[Tree]
InterProIPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR006223. GcvT.
[Graphical view]
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. gcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGCST_AERPE
AccessionPrimary (citable) accession number: Q9YBA2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: February 9, 2010
This is version 56 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents