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Protein

DNA/RNA-binding protein Alba 2

Gene

albA2

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA/RNA-binding protein Alba 2
Gene namesi
Name:albA2
Ordered Locus Names:APE_1823
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Chromosome, Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516951 – 102DNA/RNA-binding protein Alba 2Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei14N6-acetyllysineBy similarity1

Post-translational modificationi

Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity (By similarity).By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ9YAX2

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi272557.APE_1823

Structurei

Secondary structure

1102
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 10Combined sources3
Helixi16 – 27Combined sources12
Beta strandi34 – 40Combined sources7
Helixi43 – 57Combined sources15
Turni58 – 61Combined sources4
Beta strandi62 – 77Combined sources16
Beta strandi79 – 81Combined sources3
Beta strandi83 – 97Combined sources15

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2H9UX-ray2.00A1-102[»]
3U6YX-ray2.00A/C1-102[»]
ProteinModelPortaliQ9YAX2
SMRiQ9YAX2
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9YAX2

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like Alba family.Curated

Phylogenomic databases

eggNOGiarCOG01753 Archaea
COG1581 LUCA
HOGENOMiHOG000105803
KOiK03622
OMAiQFNEGAK
OrthoDBiPOG093Z0HGS

Family and domain databases

Gene3Di3.30.110.20, 1 hit
HAMAPiMF_01122 AlbA, 1 hit
InterProiView protein in InterPro
IPR036882 Alba-like_dom_sf
IPR013795 DNA/RNA-bd_Alba
IPR002775 DNA/RNA-bd_Alba-like
PANTHERiPTHR13516:SF4 PTHR13516:SF4, 1 hit
PfamiView protein in Pfam
PF01918 Alba, 1 hit
PIRSFiPIRSF028732 Alba, 1 hit
SUPFAMiSSF82704 SSF82704, 1 hit
TIGRFAMsiTIGR00285 TIGR00285, 1 hit

Sequencei

Sequence statusi: Complete.

Q9YAX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACEGAPEVR IGRKPVMNYV LAILTTLMEQ GTNQVVVKAR GRNINRAVDA
60 70 80 90 100
VEIVRKRFAK NIEIKDIKID SQEIEVQTPE GQTRTRRVSS IEICLEKAGE

SA
Length:102
Mass (Da):11,380
Last modified:November 1, 1999 - v1
Checksum:iF3F5103D9E775D10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA Translation: BAA80826.1
PIRiE72567

Genome annotation databases

EnsemblBacteriaiBAA80826; BAA80826; APE_1823
KEGGiape:APE_1823

Similar proteinsi

Entry informationi

Entry nameiALBA2_AERPE
AccessioniPrimary (citable) accession number: Q9YAX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 9, 2003
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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