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Protein

DNA/RNA-binding protein Alba 2

Gene

albA2

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

DNA-binding, RNA-binding

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1229-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA/RNA-binding protein Alba 2
Gene namesi
Name:albA2
Ordered Locus Names:APE_1823
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 102102DNA/RNA-binding protein Alba 2PRO_0000151695Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei14 – 141N6-acetyllysineBy similarity

Post-translational modificationi

Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity (By similarity).By similarity

Keywords - PTMi

Acetylation

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi272557.APE_1823.

Structurei

Secondary structure

1
102
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi8 – 103Combined sources
Helixi16 – 2712Combined sources
Beta strandi34 – 407Combined sources
Helixi43 – 5715Combined sources
Turni58 – 614Combined sources
Beta strandi62 – 7716Combined sources
Beta strandi79 – 813Combined sources
Beta strandi83 – 9715Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H9UX-ray2.00A1-102[»]
3U6YX-ray2.00A/C1-102[»]
ProteinModelPortaliQ9YAX2.
SMRiQ9YAX2. Positions 2-102.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9YAX2.

Family & Domainsi

Sequence similaritiesi

Belongs to the histone-like Alba family.Curated

Phylogenomic databases

eggNOGiarCOG01753. Archaea.
COG1581. LUCA.
HOGENOMiHOG000105803.
KOiK03622.
OMAiYVIATVM.

Family and domain databases

Gene3Di3.30.110.20. 1 hit.
HAMAPiMF_01122. AlbA.
InterProiIPR013795. DNA/RNA-bd_Alba.
IPR002775. DNA/RNA-bd_Alba-like.
[Graphical view]
PfamiPF01918. Alba. 1 hit.
[Graphical view]
PIRSFiPIRSF028732. Alba. 1 hit.
SUPFAMiSSF82704. SSF82704. 1 hit.
TIGRFAMsiTIGR00285. TIGR00285. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YAX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACEGAPEVR IGRKPVMNYV LAILTTLMEQ GTNQVVVKAR GRNINRAVDA
60 70 80 90 100
VEIVRKRFAK NIEIKDIKID SQEIEVQTPE GQTRTRRVSS IEICLEKAGE

SA
Length:102
Mass (Da):11,380
Last modified:November 1, 1999 - v1
Checksum:iF3F5103D9E775D10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80826.1.
PIRiE72567.

Genome annotation databases

EnsemblBacteriaiBAA80826; BAA80826; APE_1823.
KEGGiape:APE_1823.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA80826.1.
PIRiE72567.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2H9UX-ray2.00A1-102[»]
3U6YX-ray2.00A/C1-102[»]
ProteinModelPortaliQ9YAX2.
SMRiQ9YAX2. Positions 2-102.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272557.APE_1823.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA80826; BAA80826; APE_1823.
KEGGiape:APE_1823.

Phylogenomic databases

eggNOGiarCOG01753. Archaea.
COG1581. LUCA.
HOGENOMiHOG000105803.
KOiK03622.
OMAiYVIATVM.

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1229-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9YAX2.

Family and domain databases

Gene3Di3.30.110.20. 1 hit.
HAMAPiMF_01122. AlbA.
InterProiIPR013795. DNA/RNA-bd_Alba.
IPR002775. DNA/RNA-bd_Alba-like.
[Graphical view]
PfamiPF01918. Alba. 1 hit.
[Graphical view]
PIRSFiPIRSF028732. Alba. 1 hit.
SUPFAMiSSF82704. SSF82704. 1 hit.
TIGRFAMsiTIGR00285. TIGR00285. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiALBA2_AERPE
AccessioniPrimary (citable) accession number: Q9YAX2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 9, 2003
Last sequence update: November 1, 1999
Last modified: November 11, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.