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Protein

Probable cysteine desulfurase

Gene

csd

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactori

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1367-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cysteine desulfurase (EC:2.8.1.7)
Gene namesi
Name:csd
Ordered Locus Names:APE_2023
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411Probable cysteine desulfurasePRO_0000150325Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei221 – 2211N6-(pyridoxal phosphate)lysineBy similarity

Interactioni

Protein-protein interaction databases

STRINGi272557.APE_2023.

Structurei

3D structure databases

ProteinModelPortaliQ9YAB6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi246 – 2494Poly-Gly

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG00065. Archaea.
COG0520. LUCA.
HOGENOMiHOG000017511.
KOiK11717.
OMAiAEKVHGK.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000192. Aminotrans_V_dom.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9YAB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRFSCYEVR SEFPELERGI VYLDNAASTL KPRRVVEAMR EFSYRSYANV
60 70 80 90 100
HRGVHRLSME ASKAYEDAHE VVARLVGGSW DEVVFTRNTT EAMQLAALTL
110 120 130 140 150
AYNGLLRGGE VLVTAADHHS TLLPWVRAAR LGGGRARILP LDGRGVPRWD
160 170 180 190 200
LLEDYITEDT RAVAVGHVSN VTGVVAPVED IVKAAKKVGA LVVLDSAQGV
210 220 230 240 250
PHLPVDFRRM GVDMAAFSGH KMLGPTGIGV LWARRDLLEE LEPPLGGGGT
260 270 280 290 300
VSRVRLQGGS VEIEWEEPPW KFEAGTPPII EAVGLAEAAN MLMEIGMEHV
310 320 330 340 350
ARHEDELTSH TMKLLEPLYS EGLIRYVGPD KPGERHGIVS ITTHLKSPDE
360 370 380 390 400
LGLLLDRRGI AVRTGLHCAH ILHDHVDASM GSVWASFYIY NCKEDAERLA
410
EALEEILTTR R
Length:411
Mass (Da):45,293
Last modified:November 1, 1999 - v1
Checksum:i7EDBF180D99B1399
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA81033.1.
PIRiA72506.

Genome annotation databases

EnsemblBacteriaiBAA81033; BAA81033; APE_2023.
KEGGiape:APE_2023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA81033.1.
PIRiA72506.

3D structure databases

ProteinModelPortaliQ9YAB6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272557.APE_2023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA81033; BAA81033; APE_2023.
KEGGiape:APE_2023.

Phylogenomic databases

eggNOGiarCOG00065. Archaea.
COG0520. LUCA.
HOGENOMiHOG000017511.
KOiK11717.
OMAiAEKVHGK.

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1367-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000192. Aminotrans_V_dom.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiCSD_AERPE
AccessioniPrimary (citable) accession number: Q9YAB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1999
Last modified: November 11, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.