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Protein

DNA polymerase sliding clamp 2

Gene

pcn2

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clamp 2UniRule annotation
Alternative name(s):
DNA polymerase sliding clamp B1UniRule annotation
Proliferating cell nuclear antigen homolog 3UniRule annotation
Short name:
PCNA 3UniRule annotation
Gene namesi
Name:pcn2UniRule annotation
Synonyms:pcnB1
Ordered Locus Names:APE_2182
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491901 – 251DNA polymerase sliding clamp 2Add BLAST251

Proteomic databases

PRIDEiQ9Y9V7

Interactioni

Subunit structurei

Heterotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA (By similarity).By similarity

Protein-protein interaction databases

STRINGi272557.APE_2182

Structurei

3D structure databases

ProteinModelPortaliQ9Y9V7
SMRiQ9Y9V7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000232351
KOiK04802
OMAiNASKMKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF00705 PCNA_N, 1 hit
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Y9V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRLVYTASS KFKYIAQTLA KINDEGVFEF SLDGLRAWIM SPDKTSLAIL
60 70 80 90 100
EMPSLSFEEY MVEEEMRVVL RTDELNKISK RATRNDDIIF QWNAEEQALE
110 120 130 140 150
VELRDRKLGF SRKFLVPATS VGAEEMRRLK LEPTVSFTIL TDDLKAMIQD
160 170 180 190 200
VKVVGDFAEF EASEGQVVVR SQAEEKEYEW VMKPGDVLLS LEVEEDAKSI
210 220 230 240 250
YSRQVLEIAT KPVGAAESVK VSFASDYPMK IEYTFPNGER MELYMAPSLA

G
Length:251
Mass (Da):28,618
Last modified:November 1, 1999 - v1
Checksum:iAA93412CB3847A1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA Translation: BAA81193.1
PIRiA72526

Genome annotation databases

EnsemblBacteriaiBAA81193; BAA81193; APE_2182
KEGGiape:APE_2182

Similar proteinsi

Entry informationi

Entry nameiPCNA2_AERPE
AccessioniPrimary (citable) accession number: Q9Y9V7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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