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Q9Y8T6 (TRPF_AERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:APE_2547
OrganismAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP]
Taxonomic identifier272557 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 215215N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154397

Sequences

Sequence LengthMass (Da)Tools
Q9Y8T6 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: EB30A27AEACC51E8

FASTA21522,622
        10         20         30         40         50         60 
MVKVKICGVK KLESALQLDG LVDYIGFVHS LLGGPRSVPL EAARIMASQI EKSKTVLVVH 

        70         80         90        100        110        120 
GSSPSYAAAA ADGFDVLQYH EPLLPSSAAS LQATLDPLGV TLAVVVEYTG SAWKPQEPCG 

       130        140        150        160        170        180 
YINELNKEGV EPEYILLDTT KGLRDRIPLN EAAKASRCSH RVGLAGGLTP RDACKAVETG 

       190        200        210 
VSLIDVSRGV ETGVPGVKDP LLSAELIMGA KRCSS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000002 Genomic DNA. Translation: BAA81564.1.
PIRD72488.
RefSeqNP_148686.1. NC_000854.2.

3D structure databases

ProteinModelPortalQ9Y8T6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272557.APE_2547.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA81564; BAA81564; APE_2547.
GeneID1445493.
KEGGape:APE_2547.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.
OMAVKICGVA.

Enzyme and pathway databases

BioCycAPER272557:GJD6-1707-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_AERPE
AccessionPrimary (citable) accession number: Q9Y8T6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: November 1, 1999
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways