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Q9Y8T6

- TRPF_AERPE

UniProt

Q9Y8T6 - TRPF_AERPE

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciAPER272557:GJD6-1707-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:APE_2547
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
ProteomesiUP000002518: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154397Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272557.APE_2547.

Structurei

3D structure databases

ProteinModelPortaliQ9Y8T6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPYMIDVA.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Y8T6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKVKICGVK KLESALQLDG LVDYIGFVHS LLGGPRSVPL EAARIMASQI
60 70 80 90 100
EKSKTVLVVH GSSPSYAAAA ADGFDVLQYH EPLLPSSAAS LQATLDPLGV
110 120 130 140 150
TLAVVVEYTG SAWKPQEPCG YINELNKEGV EPEYILLDTT KGLRDRIPLN
160 170 180 190 200
EAAKASRCSH RVGLAGGLTP RDACKAVETG VSLIDVSRGV ETGVPGVKDP
210
LLSAELIMGA KRCSS
Length:215
Mass (Da):22,622
Last modified:November 1, 1999 - v1
Checksum:iEB30A27AEACC51E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA81564.1.
PIRiD72488.
RefSeqiNP_148686.1. NC_000854.2.
WP_010867077.1. NC_000854.2.

Genome annotation databases

EnsemblBacteriaiBAA81564; BAA81564; APE_2547.
GeneIDi1445493.
KEGGiape:APE_2547.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA. Translation: BAA81564.1 .
PIRi D72488.
RefSeqi NP_148686.1. NC_000854.2.
WP_010867077.1. NC_000854.2.

3D structure databases

ProteinModelPortali Q9Y8T6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272557.APE_2547.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA81564 ; BAA81564 ; APE_2547 .
GeneIDi 1445493.
KEGGi ape:APE_2547.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PYMIDVA.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci APER272557:GJD6-1707-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiTRPF_AERPE
AccessioniPrimary (citable) accession number: Q9Y8T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3