Q9Y827 (YEX5_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C1A6.05c
EC=3.1.1.-

Gene names

ORF Names:

SPAC1A6.05c

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	483 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Cytoplasm. Membrane; Single-pass membrane protein Potential Ref.2.
Sequence similarities	Contains 1 patatin domain.

Ontologies

Keywords
Biological process	Lipid degradation Lipid metabolism
Cellular component	Cytoplasm Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	triglyceride catabolic process Inferred from sequence orthology. Source: PomBase triglyceride mobilization Inferred from sequence orthology. Source: PomBase
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW lipid particle Inferred from sequence orthology. Source: PomBase
Molecular_function	triglyceride lipase activity Inferred from sequence orthology. Source: PomBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 483	483	Uncharacterized protein C1A6.05c		PRO_0000317235
Regions
	Transmembrane	278 – 298	21	Helical; Potential
	Domain	141 – 340	200	Patatin

Sequences

	Sequence		Length	Mass (Da)
	Q9Y827 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: B47CD9E513EBAACF	FASTA	483	54,684
	10 20 30 40 50 60 MSKNEIKLQM EYASSYETWL EAAEKLDVIE GKYQWREQKE SDEYDYVLVE SRLHELRRHR 70 80 90 100 110 120 LSKNTRLLLG LLRNSVARDF ANMDNSRLYN YAHSGTKKLI DEFIQEVLMC LTYLEETPDL 130 140 150 160 170 180 SLDEKITEFS RLKLTTGNTA LILSGGGTFG MTHIGVLQSL HEQGLVPKII CGSSAGAIVA 190 200 210 220 230 240 CAAAVRNKEE QEILLRQFHT GDLSVFTDPN AAPPSVIQSV KQYFTRGCVL DISHLERVMK 250 260 270 280 290 300 LLIGDFTFQE AYDRSGYILN VTVSCGSLFE MPSLLNYITA PNVLVWSAVV ATCSVPFLFK 310 320 330 340 350 360 RATLWERDPL TREVSAFCVT DAPLWMDGSV DNDIPHAKLT ELFHVNHFIV SQVNFHIVPF 370 380 390 400 410 420 IMDPTSHNWV ERCCKKAIDL AAQEVSLTFR LFAELGIFSV LFTKLQSVIT QKYSGDITII 430 440 450 460 470 480 PRLNYREVNK VIKNPTPSFL LDAATRGKRG TWTKVPVTRN HCAIEILIAA AYTRLIKRSK SLK

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329670 Genomic DNA. Translation: CAB16355.2.
PIR	T38008.
RefSeq	NP_593197.1. NM_001018593.2.
3D structure databases
ProteinModelPortal	Q9Y827.
ModBase	Search...
Protein-protein interaction databases
STRING	4896.SPAC1A6.05c-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPAC1A6.05c.1; SPAC1A6.05c.1:pep; SPAC1A6.05c.
GeneID	2542205.
KEGG	spo:SPAC1A6.05c.
Organism-specific databases
PomBase	SPAC1A6.05c.
Phylogenomic databases
eggNOG	COG1752.
HOGENOM	HOG000225801.
KO	K14674.
OMA	HITILPS.
OrthoDB	EOG4BZR9Q.
Family and domain databases
InterPro	IPR016035. Acyl_Trfase/lysoPLipase. IPR002641. Patatin/PLipase_A2-rel. IPR021771. Triacylglycerol_lipase. [Graphical view]
Pfam	PF11815. DUF3336. 1 hit. PF01734. Patatin. 1 hit. [Graphical view]
SUPFAM	SSF52151. Acyl_Trfase/lysoPlipase. 1 hit.
ProtoNet	Search...
Other
NextBio	20803275.

Entry information

Entry name

YEX5_SCHPO

Accession

Primary (citable) accession number: Q9Y827

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 1, 1999
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program