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Protein

Probable glutamine--tRNA ligase

Gene

qrs1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei302L-glutamineBy similarity1
Binding sitei447L-glutamineBy similarity1
Binding sitei466ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi270 – 272ATPBy similarity3
Nucleotide bindingi276 – 282ATPBy similarity7
Nucleotide bindingi495 – 496ATPBy similarity2
Nucleotide bindingi503 – 505ATPBy similarity3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18By similarity)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Name:qrs1
ORF Names:SPBC342.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC342.02
PomBaseiSPBC342.02 qrs1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958651 – 811Probable glutamine--tRNA ligaseAdd BLAST811

Proteomic databases

MaxQBiQ9Y7Y8
PaxDbiQ9Y7Y8
PRIDEiQ9Y7Y8

Interactioni

Protein-protein interaction databases

BioGridi277494, 1 interactor
STRINGi4896.SPBC342.02.1

Structurei

3D structure databases

ProteinModelPortaliQ9Y7Y8
SMRiQ9Y7Y8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi269 – 279"HIGH" regionAdd BLAST11
Motifi502 – 506"KMSKS" region5

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000259233
InParanoidiQ9Y7Y8
KOiK01886
OMAiVTHSICT
OrthoDBiEOG092C0PFH
PhylomeDBiQ9Y7Y8

Family and domain databases

Gene3Di2.40.240.10, 2 hits
3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR007638 Gln-tRNA-synth_Ib_RNA-bd_2
IPR007639 Gln-tRNA-synth_Ib_RNA-bd_N
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PF04558 tRNA_synt_1c_R1, 1 hit
PF04557 tRNA_synt_1c_R2, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Y7Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQDYEELRA KFTKIGLNET TVKDTLKNKK LSSSLNKVIE ETNVGSSGCD
60 70 80 90 100
RTIGNLLFTL ANASLKQKDP KSNAHEAFIA SKIVSGDLKT NLQVNAAITY
110 120 130 140 150
CKDKDTIDES EFDKETGVGV VLTPEQIEQL VGDYVAENKS KILEQRYQLL
160 170 180 190 200
NPSASALRQH ALLKWAPQLE VKQTLDRKFL ELLGPKTEQD AAAGKKKGAK
210 220 230 240 250
AKNSKQKTVD SGKAKEQKIV SEQSKKYNMF EEGFLAKLHK PGGNTQLIPE
260 270 280 290 300
RMKEHLQATG GGVVTRFPPE PNGYLHIGHS KAIAVNFGFA RYHNGVCYLR
310 320 330 340 350
FDDTNPEAEE ERYFESIKDL VAWLGFQPYK ITYSSDYFDK LYELAEELIK
360 370 380 390 400
RDKAYVCHCT DAEIKKARGG EERGPRYACV HRDRPIEESL LEFRNMRDGK
410 420 430 440 450
YQPKEAILRM KQDLSDGNPQ MWDLIAYRVL NSPHPRTGDK WKIYPTYDFT
460 470 480 490 500
HCLVDSFENI SHSLCTTEFI LSRVSYEWLC NALEVYCPAQ REYGRLNVVG
510 520 530 540 550
TLMSKRKIMK LVKEGYVHGW NDPRLYTLVA LRRRGVPPGA ILEFVSEVGV
560 570 580 590 600
TTAVSNIEVA RFENCVRKFL ENSVPRLMFL PDPIKVTLEN LDDSYREQIE
610 620 630 640 650
IPFNPKDPSM GSRSAFLTKH IYIDRSDFRE EASSDFFRLT LGQPVGLFRA
660 670 680 690 700
SHPVVAKRVV KNDEGEPIEI IAEYDASSSK KPKTFIQWVS RDKESNSPVL
710 720 730 740 750
IAETRLFNNL FKCDNPAALK EQELAAQLNP ESEVVLKNSI IEPGIYDLIK
760 770 780 790 800
SAPWPKTDSS AGVDKAENPE SVRFQAMRVG YFCLDEDTKK PNHLVLNRIV
810
SLREDSAKNK N
Length:811
Mass (Da):92,073
Last modified:November 1, 1999 - v1
Checksum:iAA346369990F94CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB46772.1
PIRiT40275
RefSeqiNP_596745.1, NM_001023765.2

Genome annotation databases

EnsemblFungiiSPBC342.02.1; SPBC342.02.1:pep; SPBC342.02
GeneIDi2540978
KEGGispo:SPBC342.02

Similar proteinsi

Entry informationi

Entry nameiSYQ_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7Y8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: June 20, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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