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Q9Y7Y8 (SYQ_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:qrs1
ORF Names:SPBC342.02
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length811 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Subcellular location

Cytoplasm Ref.2.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 811811Probable glutamine--tRNA ligase
PRO_0000195865

Regions

Motif269 – 27911"HIGH" region
Motif502 – 5065"KMSKS" region

Sites

Binding site5051ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Y7Y8 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: AA346369990F94CE

FASTA81192,073
        10         20         30         40         50         60 
MDQDYEELRA KFTKIGLNET TVKDTLKNKK LSSSLNKVIE ETNVGSSGCD RTIGNLLFTL 

        70         80         90        100        110        120 
ANASLKQKDP KSNAHEAFIA SKIVSGDLKT NLQVNAAITY CKDKDTIDES EFDKETGVGV 

       130        140        150        160        170        180 
VLTPEQIEQL VGDYVAENKS KILEQRYQLL NPSASALRQH ALLKWAPQLE VKQTLDRKFL 

       190        200        210        220        230        240 
ELLGPKTEQD AAAGKKKGAK AKNSKQKTVD SGKAKEQKIV SEQSKKYNMF EEGFLAKLHK 

       250        260        270        280        290        300 
PGGNTQLIPE RMKEHLQATG GGVVTRFPPE PNGYLHIGHS KAIAVNFGFA RYHNGVCYLR 

       310        320        330        340        350        360 
FDDTNPEAEE ERYFESIKDL VAWLGFQPYK ITYSSDYFDK LYELAEELIK RDKAYVCHCT 

       370        380        390        400        410        420 
DAEIKKARGG EERGPRYACV HRDRPIEESL LEFRNMRDGK YQPKEAILRM KQDLSDGNPQ 

       430        440        450        460        470        480 
MWDLIAYRVL NSPHPRTGDK WKIYPTYDFT HCLVDSFENI SHSLCTTEFI LSRVSYEWLC 

       490        500        510        520        530        540 
NALEVYCPAQ REYGRLNVVG TLMSKRKIMK LVKEGYVHGW NDPRLYTLVA LRRRGVPPGA 

       550        560        570        580        590        600 
ILEFVSEVGV TTAVSNIEVA RFENCVRKFL ENSVPRLMFL PDPIKVTLEN LDDSYREQIE 

       610        620        630        640        650        660 
IPFNPKDPSM GSRSAFLTKH IYIDRSDFRE EASSDFFRLT LGQPVGLFRA SHPVVAKRVV 

       670        680        690        700        710        720 
KNDEGEPIEI IAEYDASSSK KPKTFIQWVS RDKESNSPVL IAETRLFNNL FKCDNPAALK 

       730        740        750        760        770        780 
EQELAAQLNP ESEVVLKNSI IEPGIYDLIK SAPWPKTDSS AGVDKAENPE SVRFQAMRVG 

       790        800        810 
YFCLDEDTKK PNHLVLNRIV SLREDSAKNK N 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAB46772.1.
PIRT40275.
RefSeqNP_596745.1. NM_001023765.2.

3D structure databases

ProteinModelPortalQ9Y7Y8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid277494. 2 interactions.
MINTMINT-4720158.
STRING4896.SPBC342.02-1.

Proteomic databases

MaxQBQ9Y7Y8.
PaxDbQ9Y7Y8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC342.02.1; SPBC342.02.1:pep; SPBC342.02.
GeneID2540978.
KEGGspo:SPBC342.02.

Organism-specific databases

PomBaseSPBC342.02.

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259233.
KOK01886.
OMAEGHVRDW.
OrthoDBEOG7MD4ZK.
PhylomeDBQ9Y7Y8.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802093.
PROQ9Y7Y8.

Entry information

Entry nameSYQ_SCHPO
AccessionPrimary (citable) accession number: Q9Y7Y8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: May 14, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries