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Protein

Actin-like protein arp5

Gene

arp5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

GO - Biological processi

  • ATP-dependent chromatin remodeling Source: PomBase
  • cellular response to DNA damage stimulus Source: UniProtKB-KW
  • chromatin remodeling Source: PomBase
  • regulation of nucleosome density Source: PomBase
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionChromatin regulator
Biological processDNA damage, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-like protein arp5
Gene namesi
Name:arp5
ORF Names:SPBC365.10
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC365.10
PomBaseiSPBC365.10 arp5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003103071 – 721Actin-like protein arp5Add BLAST721

Proteomic databases

MaxQBiQ9Y7X8
PaxDbiQ9Y7X8
PRIDEiQ9Y7X8

Interactioni

Subunit structurei

Component of the INO80 chromatin remodeling complex.1 Publication

Protein-protein interaction databases

BioGridi277546, 1 interactor
STRINGi4896.SPBC365.10.1

Structurei

3D structure databases

ProteinModelPortaliQ9Y7X8
SMRiQ9Y7X8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili266 – 368Sequence analysisAdd BLAST103

Sequence similaritiesi

Belongs to the actin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000171615
InParanoidiQ9Y7X8
KOiK11672
OMAiNVGGYHI
OrthoDBiEOG092C0R1R
PhylomeDBiQ9Y7X8

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR027664 Arp5
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF16 PTHR11937:SF16, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 2 hits
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Y7X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIYAVREPV FSGPTPSFQN VSNDIPLVID NGSWQLRAGW GGEKDPKLVF
60 70 80 90 100
DNLVSRYRDR KLSRTSTLVG NDTLIEVGSR SIARSPFERN VISNWDLMEQ
110 120 130 140 150
VLDYTFLKLG IDRMEHPICM TEPLANPTYV RSTMTELLFE LYNAPSVAYG
160 170 180 190 200
IDGLFSFYHN TKPSSSGIVL NLGNAASHVI PVLNGERILS EAKRISWGGS
210 220 230 240 250
QSSSYLLKLF QIKYPSFPIK MLPSQAELLM HDHCHVSSDY THDIAHALDR
260 270 280 290 300
DILERDEIVL QFPYTEAAAQ EKSQEELELI AERKRESGRR LQAQAAIKRK
310 320 330 340 350
EKAAERDREL ATLTELQQQS LVLSRRAFQR ALEEAGFEDE SQLNAQVKNV
360 370 380 390 400
QAKIRRAQRD QQRQEESEGS LDVTEIDVEQ AFPLLNVPDA ELDEAGLRQK
410 420 430 440 450
RHQRLMKANY DARVRAKAEK AIEEAAEAER AEADERLRLE NFSTWVNEKR
460 470 480 490 500
ETHKILLEKI SKNKRLKFEL NDRKSHASQM RMKSLATLAS EQPIQKRKRK
510 520 530 540 550
DQSEDNFGAR DEDWKVYHDV LTAEQLEEER KKLLDQIYSL EKQLLEYDSQ
560 570 580 590 600
FTQANTYDTL NDPRATLLYA FTRGVSDFDV NDVAQAFQLH LNVEQIRVPE
610 620 630 640 650
VIFSPSIVGI DQAGILEIMR SILQRHSLEE QQKLVSNVLI TGGLGSLPGM
660 670 680 690 700
ETRIKRELTS IMPVGSSINV FRASNPLLDA WKGASEWSVT EKFKAAKVTR
710 720
EEYLEKGPEY IKEHSLGNIN S
Length:721
Mass (Da):82,364
Last modified:November 1, 1999 - v1
Checksum:iB847A16E87A9A148
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB44762.1
PIRiT40317
RefSeqiNP_596039.1, NM_001021949.2

Genome annotation databases

EnsemblFungiiSPBC365.10.1; SPBC365.10.1:pep; SPBC365.10
GeneIDi2541031
KEGGispo:SPBC365.10

Similar proteinsi

Entry informationi

Entry nameiARP5_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7X8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 1, 1999
Last modified: April 25, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health