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Protein

Transcription factor bye1

Gene

bye1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Negative regulator of transcription elongation.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri20 – 6950PHD-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor bye1
Gene namesi
Name:bye1
ORF Names:SPCC645.13
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC645.13.
PomBaseiSPCC645.13.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation1 Publication

GO - Cellular componenti

  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 721721Transcription factor bye1PRO_0000116549Add
BLAST

Proteomic databases

MaxQBiQ9Y7V2.

Interactioni

Protein-protein interaction databases

BioGridi275285. 22 interactions.
MINTiMINT-4719617.

Structurei

3D structure databases

ProteinModelPortaliQ9Y7V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini217 – 347131TFIIS centralPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the BYE1 family.Curated
Contains 1 PHD-type zinc finger.PROSITE-ProRule annotation
Contains 1 TFIIS central domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri20 – 6950PHD-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiQ9Y7V2.
OMAiRIDIQLA.
OrthoDBiEOG7R8390.
PhylomeDBiQ9Y7V2.

Family and domain databases

Gene3Di1.10.472.30. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR012921. SPOC_C.
IPR003618. TFIIS_cen_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
PF07744. SPOC. 1 hit.
PF07500. TFIIS_M. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
SM00510. TFS2M. 1 hit.
[Graphical view]
SUPFAMiSSF46942. SSF46942. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEiPS51321. TFIIS_CENTRAL. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Y7V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRKSTRRTA KASEKPPETV VRCVCKSQED IGDTWVQCDG CDCWQHASCV
60 70 80 90 100
GLADKDIPES YYCEVCHSRS DVSSQVQNSP NKDEEHQTAD LLASNEGNEK
110 120 130 140 150
NNEENNVVSS DSKEAITKES GAELESSEPA STNSNVGMTT RSGRQSPRTP
160 170 180 190 200
IGSTTPKSSH SPPSTRKRRG SVGTTATHTK RSKNAPKTSP KDASNETADQ
210 220 230 240 250
EKELSLHTSI DEIQNPVRKS VAKAWVSVFE KIIEKAKLEG VQGLEDLNST
260 270 280 290 300
SLALQLEHIM FMVLSYTTDH SLTPNNKYRE KFRALRFNLV DDKNPAFRAR
310 320 330 340 350
VLKNEISFND LVNLSSEEMA NPDLKNLAEE IRQQSTENTV IKQHLIAPRD
360 370 380 390 400
RLLDEDKLTQ QDELGIAEND DAMFPKPPGE LVAPISIAEE EPTIDSKSPT
410 420 430 440 450
LPEHNPLSED DTSNGDKAAK RKGSFNDTKP IVNVPSIVEI DDPTILDIVE
460 470 480 490 500
EEPLARNDSF SSPYSPAEDM AEESEFFGMK EKIWTGKVKM ATVSEFHANA
510 520 530 540 550
LNLFGDVSAS HLFEILSATA LIEGRISVSS VLQYFHALRK TPSKEIIAVL
560 570 580 590 600
FVPTEQNSQG FDILYDYFVK RNRYGVLHSK SNSVKDAYII PMPSGNSVPE
610 620 630 640 650
LLDLLPKVDL PKDRNFQYFM GLFVLNKSSS RHESVERATP ITTSTNGIPS
660 670 680 690 700
TYQSASGTPT NPVHSYPSLE SIINALTPSD MLLIKDVVEN NPQIRANPSL
710 720
AINPQFMQNA ISAAQKKASK Q
Length:721
Mass (Da):79,739
Last modified:February 1, 2005 - v3
Checksum:i32EA032A41BE0B08
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti97 – 1004GNEK → RERE in BAA87257 (PubMed:10759889).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB39909.1.
AB027885 Genomic DNA. Translation: BAA87189.1.
AB027953 Genomic DNA. Translation: BAA87257.1.
PIRiT41530.
RefSeqiNP_588122.1. NM_001023112.2.

Genome annotation databases

EnsemblFungiiSPCC645.13.1; SPCC645.13.1:pep; SPCC645.13.
GeneIDi2538700.
KEGGispo:SPCC645.13.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB39909.1.
AB027885 Genomic DNA. Translation: BAA87189.1.
AB027953 Genomic DNA. Translation: BAA87257.1.
PIRiT41530.
RefSeqiNP_588122.1. NM_001023112.2.

3D structure databases

ProteinModelPortaliQ9Y7V2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275285. 22 interactions.
MINTiMINT-4719617.

Proteomic databases

MaxQBiQ9Y7V2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC645.13.1; SPCC645.13.1:pep; SPCC645.13.
GeneIDi2538700.
KEGGispo:SPCC645.13.

Organism-specific databases

EuPathDBiFungiDB:SPCC645.13.
PomBaseiSPCC645.13.

Phylogenomic databases

InParanoidiQ9Y7V2.
OMAiRIDIQLA.
OrthoDBiEOG7R8390.
PhylomeDBiQ9Y7V2.

Miscellaneous databases

NextBioi20799886.
PROiQ9Y7V2.

Family and domain databases

Gene3Di1.10.472.30. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR012921. SPOC_C.
IPR003618. TFIIS_cen_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
PF07744. SPOC. 1 hit.
PF07500. TFIIS_M. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
SM00510. TFS2M. 1 hit.
[Graphical view]
SUPFAMiSSF46942. SSF46942. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEiPS51321. TFIIS_CENTRAL. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
    Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
    Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 53-199, SUBCELLULAR LOCATION.
    Strain: ATCC 38364 / 968.

Entry informationi

Entry nameiBYE1_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7V2
Secondary accession number(s): Q1MXG6, Q9UTW8, Q9UU07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: May 11, 2016
This is version 97 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.