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Protein

Aromatic amino acid aminotransferase C569.07

Gene

SPCC569.07

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Has aromatic amino acid transaminase activity.By similarity

Catalytic activityi

An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.

Cofactori

pyridoxal 5'-phosphateBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

ReactomeiR-SPO-71064. Lysine catabolism.
R-SPO-71240. Tryptophan catabolism.

Names & Taxonomyi

Protein namesi
Recommended name:
Aromatic amino acid aminotransferase C569.07 (EC:2.6.1.57)
Gene namesi
ORF Names:SPCC569.07
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC569.07.
PomBaseiSPCC569.07.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003084911 – 470Aromatic amino acid aminotransferase C569.07Add BLAST470

Proteomic databases

MaxQBiQ9Y7S6.
PRIDEiQ9Y7S6.

Interactioni

Protein-protein interaction databases

BioGridi275360. 5 interactors.
MINTiMINT-4718628.

Structurei

3D structure databases

ProteinModelPortaliQ9Y7S6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000223057.
InParanoidiQ9Y7S6.
KOiK00838.
OMAiIPHGQNP.
OrthoDBiEOG092C1J5R.
PhylomeDBiQ9Y7S6.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Y7S6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNLKKKYQH HLSLESASRE YGPFQMLGRI QSDSDIKMLS FAGGEPNPSK
60 70 80 90 100
FPIHKLSVSF PEVNSWEKDT NKDATVSYEL SNNANEGSLD LLGALQYGQC
110 120 130 140 150
QGIPELVKFI KDHVGQIHMP QYKDWDIKIT NGNTIGLEYC LRLLVNRGDC
160 170 180 190 200
ILIEKYTYPA AITAMRPLGV KFIPIDMDEN GMLPESFEKV METWDSSLGA
210 220 230 240 250
RPHVLYTIPT GQNPTGSTLT LERRKKFLTL AKKYDIIIVE DEPYYFLQME
260 270 280 290 300
KYDANWKPDK QAFNISSFKK KLIPSLLHLD TDGRVLRVDS FSKLIVPGLR
310 320 330 340 350
LGWITGNSLF IDRITRYAEV CTESPSGVSQ VVLYAILNRW GQNGFLEWLQ
360 370 380 390 400
DLQNSYTMRR NALLLAADKH LPKSVCKYHS PKAGLFLWVE LDKNRLICSN
410 420 430 440 450
MDKSISEIEM EIFVELVNNG VKPVCGQLFM GEPNSADKIF FRFAYSLADL
460 470
STFEAGLERF TSTIQKYFQL
Length:470
Mass (Da):53,614
Last modified:November 1, 1999 - v1
Checksum:iE361A1885B80879D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB42068.1.
PIRiT41409.
RefSeqiNP_588566.1. NM_001023553.2.

Genome annotation databases

EnsemblFungiiSPCC569.07.1; SPCC569.07.1:pep; SPCC569.07.
GeneIDi2538779.
KEGGispo:SPCC569.07.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB42068.1.
PIRiT41409.
RefSeqiNP_588566.1. NM_001023553.2.

3D structure databases

ProteinModelPortaliQ9Y7S6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275360. 5 interactors.
MINTiMINT-4718628.

Proteomic databases

MaxQBiQ9Y7S6.
PRIDEiQ9Y7S6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC569.07.1; SPCC569.07.1:pep; SPCC569.07.
GeneIDi2538779.
KEGGispo:SPCC569.07.

Organism-specific databases

EuPathDBiFungiDB:SPCC569.07.
PomBaseiSPCC569.07.

Phylogenomic databases

HOGENOMiHOG000223057.
InParanoidiQ9Y7S6.
KOiK00838.
OMAiIPHGQNP.
OrthoDBiEOG092C1J5R.
PhylomeDBiQ9Y7S6.

Enzyme and pathway databases

ReactomeiR-SPO-71064. Lysine catabolism.
R-SPO-71240. Tryptophan catabolism.

Miscellaneous databases

PROiQ9Y7S6.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAATR3_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7S6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 1, 1999
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.