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Q9Y7N6

- PLB5_SCHPO

UniProt

Q9Y7N6 - PLB5_SCHPO

Protein

Putative lysophospholipase C1450.09c

Gene

SPCC1450.09c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 3 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the release of fatty acids from lysophospholipids.By similarity

    Catalytic activityi

    2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

    GO - Molecular functioni

    1. lysophospholipase activity Source: UniProtKB-EC
    2. phospholipase activity Source: PomBase

    GO - Biological processi

    1. glycerophospholipid catabolic process Source: PomBase

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Lipid degradation, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative lysophospholipase C1450.09c (EC:3.1.1.5)
    Alternative name(s):
    Phospholipase B
    Gene namesi
    ORF Names:SPCC1450.09c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome III

    Organism-specific databases

    PomBaseiSPCC1450.09c.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. external side of plasma membrane Source: PomBase
    2. extracellular region Source: UniProtKB-SubCell
    3. fungal-type cell wall Source: PomBase
    4. Golgi apparatus Source: PomBase

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 623604Putative lysophospholipase C1450.09cPRO_0000024643Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi118 – 1181N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi187 – 1871N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi232 – 2321N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi256 – 2561N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi264 – 2641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi293 – 2931N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi331 – 3311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi360 – 3601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi367 – 3671N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi400 – 4001N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi403 – 4031N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi474 – 4741N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi508 – 5081N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi513 – 5131N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi537 – 5371N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi564 – 5641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi586 – 5861N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi603 – 6031N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    BioGridi275706. 32 interactions.
    MINTiMINT-4717493.
    STRINGi4896.SPCC1450.09c-1.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini67 – 607541PLA2cPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the lysophospholipase family.Curated
    Contains 1 PLA2c domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG271081.
    HOGENOMiHOG000189547.
    KOiK13333.
    OMAiANITFLH.
    OrthoDBiEOG7N37NC.
    PhylomeDBiQ9Y7N6.

    Family and domain databases

    InterProiIPR016035. Acyl_Trfase/lysoPLipase.
    IPR002642. LysoPLipase_cat_dom.
    [Graphical view]
    PfamiPF01735. PLA2_B. 1 hit.
    [Graphical view]
    SMARTiSM00022. PLAc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52151. SSF52151. 1 hit.
    PROSITEiPS51210. PLA2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9Y7N6-1 [UniParc]FASTAAdd to Basket

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    MKLSSFGLFL ALQLLPALGL PSRIDEVDVS DPELIGLLKP DNVDKPANSI    50
    PLSKRSTSPS YAPYTVACPS GSLLRPASDG LSTGEQEFVD KRVSKVNSAL 100
    ESFISKTGLK IDTKSVLNDT DGPRLGIAIS GGGFPAMLTG AGAINAFDAR 150
    NGNTTSLGGI LQSSMYLTGL SGGSWLVGSV AVNNFANITF LHDDVWNLDH 200
    SLFAPYDDAF ENFYIYQEWF EQVLQKKNAG FNVSITDLWG RALALKLVNP 250
    LTGGANTTFS SVTNETWFQD GEFPFPIIIA DNVIEGETVI PLNDTVFEFT 300
    PIEFGTWDTG VESFIPMEYT GTHLINGIPL NESCVRNFDN AGFLMGTSSN 350
    VFSGILPATN ASLTASNNTF NNAVLSFLEM LAEDQLDVGL YPNPYQGYGN 400
    ASNTTTTNPL EPYPIIELID GGSDSEGIPF WPLLHPQRDV DVIFAIDGGY 450
    QSATSGWPDG SSLVSTYERV LATNSSGVRG FPYIPDTNTF LALGLNTHPT 500
    FFGCDGRNTT AGNHTVNDDT PPLVVYFPNY PWTMYANVTT YTVQLEDTLS 550
    SGMIENAAVA ATQNNSDSFA VCVACALVQR SLERKNMSTP SQCASCFNQY 600
    CWNGTIASTT VTTYAPTVLS AKI 623
    Length:623
    Mass (Da):67,043
    Last modified:September 22, 2009 - v3
    Checksum:i7180BF849DBF0A69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAB40176.3.
    PIRiT40991.
    RefSeqiNP_588308.2. NM_001023298.3.

    Genome annotation databases

    EnsemblFungiiSPCC1450.09c.1; SPCC1450.09c.1:pep; SPCC1450.09c.
    GeneIDi2539134.
    KEGGispo:SPCC1450.09c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAB40176.3 .
    PIRi T40991.
    RefSeqi NP_588308.2. NM_001023298.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 275706. 32 interactions.
    MINTi MINT-4717493.
    STRINGi 4896.SPCC1450.09c-1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPCC1450.09c.1 ; SPCC1450.09c.1:pep ; SPCC1450.09c .
    GeneIDi 2539134.
    KEGGi spo:SPCC1450.09c.

    Organism-specific databases

    PomBasei SPCC1450.09c.

    Phylogenomic databases

    eggNOGi NOG271081.
    HOGENOMi HOG000189547.
    KOi K13333.
    OMAi ANITFLH.
    OrthoDBi EOG7N37NC.
    PhylomeDBi Q9Y7N6.

    Miscellaneous databases

    NextBioi 20800306.

    Family and domain databases

    InterProi IPR016035. Acyl_Trfase/lysoPLipase.
    IPR002642. LysoPLipase_cat_dom.
    [Graphical view ]
    Pfami PF01735. PLA2_B. 1 hit.
    [Graphical view ]
    SMARTi SM00022. PLAc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52151. SSF52151. 1 hit.
    PROSITEi PS51210. PLA2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiPLB5_SCHPO
    AccessioniPrimary (citable) accession number: Q9Y7N6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 83 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3