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Q9Y7N6

- PLB5_SCHPO

UniProt

Q9Y7N6 - PLB5_SCHPO

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Protein

Putative lysophospholipase C1450.09c

Gene

SPCC1450.09c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the release of fatty acids from lysophospholipids.By similarity

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

GO - Molecular functioni

  1. lysophospholipase activity Source: UniProtKB-EC
  2. phospholipase activity Source: PomBase

GO - Biological processi

  1. glycerophospholipid catabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Putative lysophospholipase C1450.09c (EC:3.1.1.5)
Alternative name(s):
Phospholipase B
Gene namesi
ORF Names:SPCC1450.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome III

Organism-specific databases

PomBaseiSPCC1450.09c.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. external side of plasma membrane Source: PomBase
  2. extracellular region Source: UniProtKB-KW
  3. fungal-type cell wall Source: PomBase
  4. Golgi apparatus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 623604Putative lysophospholipase C1450.09cPRO_0000024643Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi118 – 1181N-linked (GlcNAc...)Sequence Analysis
Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
Glycosylationi187 – 1871N-linked (GlcNAc...)Sequence Analysis
Glycosylationi232 – 2321N-linked (GlcNAc...)Sequence Analysis
Glycosylationi256 – 2561N-linked (GlcNAc...)Sequence Analysis
Glycosylationi264 – 2641N-linked (GlcNAc...)Sequence Analysis
Glycosylationi293 – 2931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi331 – 3311N-linked (GlcNAc...)Sequence Analysis
Glycosylationi360 – 3601N-linked (GlcNAc...)Sequence Analysis
Glycosylationi367 – 3671N-linked (GlcNAc...)Sequence Analysis
Glycosylationi400 – 4001N-linked (GlcNAc...)Sequence Analysis
Glycosylationi403 – 4031N-linked (GlcNAc...)Sequence Analysis
Glycosylationi474 – 4741N-linked (GlcNAc...)Sequence Analysis
Glycosylationi508 – 5081N-linked (GlcNAc...)Sequence Analysis
Glycosylationi513 – 5131N-linked (GlcNAc...)Sequence Analysis
Glycosylationi537 – 5371N-linked (GlcNAc...)Sequence Analysis
Glycosylationi564 – 5641N-linked (GlcNAc...)Sequence Analysis
Glycosylationi586 – 5861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi603 – 6031N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

BioGridi275706. 32 interactions.
MINTiMINT-4717493.
STRINGi4896.SPCC1450.09c-1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 607541PLA2cPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the lysophospholipase family.Curated
Contains 1 PLA2c domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG271081.
HOGENOMiHOG000189547.
InParanoidiQ9Y7N6.
KOiK13333.
OMAiANITFLH.
OrthoDBiEOG7N37NC.
PhylomeDBiQ9Y7N6.

Family and domain databases

InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamiPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTiSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiPS51210. PLA2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y7N6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLSSFGLFL ALQLLPALGL PSRIDEVDVS DPELIGLLKP DNVDKPANSI
60 70 80 90 100
PLSKRSTSPS YAPYTVACPS GSLLRPASDG LSTGEQEFVD KRVSKVNSAL
110 120 130 140 150
ESFISKTGLK IDTKSVLNDT DGPRLGIAIS GGGFPAMLTG AGAINAFDAR
160 170 180 190 200
NGNTTSLGGI LQSSMYLTGL SGGSWLVGSV AVNNFANITF LHDDVWNLDH
210 220 230 240 250
SLFAPYDDAF ENFYIYQEWF EQVLQKKNAG FNVSITDLWG RALALKLVNP
260 270 280 290 300
LTGGANTTFS SVTNETWFQD GEFPFPIIIA DNVIEGETVI PLNDTVFEFT
310 320 330 340 350
PIEFGTWDTG VESFIPMEYT GTHLINGIPL NESCVRNFDN AGFLMGTSSN
360 370 380 390 400
VFSGILPATN ASLTASNNTF NNAVLSFLEM LAEDQLDVGL YPNPYQGYGN
410 420 430 440 450
ASNTTTTNPL EPYPIIELID GGSDSEGIPF WPLLHPQRDV DVIFAIDGGY
460 470 480 490 500
QSATSGWPDG SSLVSTYERV LATNSSGVRG FPYIPDTNTF LALGLNTHPT
510 520 530 540 550
FFGCDGRNTT AGNHTVNDDT PPLVVYFPNY PWTMYANVTT YTVQLEDTLS
560 570 580 590 600
SGMIENAAVA ATQNNSDSFA VCVACALVQR SLERKNMSTP SQCASCFNQY
610 620
CWNGTIASTT VTTYAPTVLS AKI
Length:623
Mass (Da):67,043
Last modified:September 22, 2009 - v3
Checksum:i7180BF849DBF0A69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329672 Genomic DNA. Translation: CAB40176.3.
PIRiT40991.
RefSeqiNP_588308.2. NM_001023298.3.

Genome annotation databases

EnsemblFungiiSPCC1450.09c.1; SPCC1450.09c.1:pep; SPCC1450.09c.
GeneIDi2539134.
KEGGispo:SPCC1450.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329672 Genomic DNA. Translation: CAB40176.3 .
PIRi T40991.
RefSeqi NP_588308.2. NM_001023298.3.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 275706. 32 interactions.
MINTi MINT-4717493.
STRINGi 4896.SPCC1450.09c-1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPCC1450.09c.1 ; SPCC1450.09c.1:pep ; SPCC1450.09c .
GeneIDi 2539134.
KEGGi spo:SPCC1450.09c.

Organism-specific databases

PomBasei SPCC1450.09c.

Phylogenomic databases

eggNOGi NOG271081.
HOGENOMi HOG000189547.
InParanoidi Q9Y7N6.
KOi K13333.
OMAi ANITFLH.
OrthoDBi EOG7N37NC.
PhylomeDBi Q9Y7N6.

Miscellaneous databases

NextBioi 20800306.

Family and domain databases

InterProi IPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view ]
Pfami PF01735. PLA2_B. 1 hit.
[Graphical view ]
SMARTi SM00022. PLAc. 1 hit.
[Graphical view ]
SUPFAMi SSF52151. SSF52151. 1 hit.
PROSITEi PS51210. PLA2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiPLB5_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7N6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: September 22, 2009
Last modified: October 29, 2014
This is version 84 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3