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Protein

Putative lysophospholipase C1450.09c

Gene

SPCC1450.09c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the release of fatty acids from lysophospholipids.By similarity

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Putative lysophospholipase C1450.09c (EC:3.1.1.5)
Alternative name(s):
Phospholipase B
Gene namesi
ORF Names:SPCC1450.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1450.09c.
PomBaseiSPCC1450.09c.

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB-SubCell
  • fungal-type cell wall Source: PomBase
  • Golgi apparatus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000002464320 – 623Putative lysophospholipase C1450.09cAdd BLAST604

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi118N-linked (GlcNAc...)Sequence analysis1
Glycosylationi153N-linked (GlcNAc...)Sequence analysis1
Glycosylationi187N-linked (GlcNAc...)Sequence analysis1
Glycosylationi232N-linked (GlcNAc...)Sequence analysis1
Glycosylationi256N-linked (GlcNAc...)Sequence analysis1
Glycosylationi264N-linked (GlcNAc...)Sequence analysis1
Glycosylationi293N-linked (GlcNAc...)Sequence analysis1
Glycosylationi331N-linked (GlcNAc...)Sequence analysis1
Glycosylationi360N-linked (GlcNAc...)Sequence analysis1
Glycosylationi367N-linked (GlcNAc...)Sequence analysis1
Glycosylationi400N-linked (GlcNAc...)Sequence analysis1
Glycosylationi403N-linked (GlcNAc...)Sequence analysis1
Glycosylationi474N-linked (GlcNAc...)Sequence analysis1
Glycosylationi508N-linked (GlcNAc...)Sequence analysis1
Glycosylationi513N-linked (GlcNAc...)Sequence analysis1
Glycosylationi537N-linked (GlcNAc...)Sequence analysis1
Glycosylationi564N-linked (GlcNAc...)Sequence analysis1
Glycosylationi586N-linked (GlcNAc...)Sequence analysis1
Glycosylationi603N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ9Y7N6.

Interactioni

Protein-protein interaction databases

BioGridi275706. 32 interactors.
MINTiMINT-4717493.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 607PLA2cPROSITE-ProRule annotationAdd BLAST541

Sequence similaritiesi

Belongs to the lysophospholipase family.Curated
Contains 1 PLA2c domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000189547.
InParanoidiQ9Y7N6.
KOiK13333.
OMAiVCDDCNS.
OrthoDBiEOG092C2IZ9.
PhylomeDBiQ9Y7N6.

Family and domain databases

InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamiPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTiSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiPS51210. PLA2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y7N6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSSFGLFL ALQLLPALGL PSRIDEVDVS DPELIGLLKP DNVDKPANSI
60 70 80 90 100
PLSKRSTSPS YAPYTVACPS GSLLRPASDG LSTGEQEFVD KRVSKVNSAL
110 120 130 140 150
ESFISKTGLK IDTKSVLNDT DGPRLGIAIS GGGFPAMLTG AGAINAFDAR
160 170 180 190 200
NGNTTSLGGI LQSSMYLTGL SGGSWLVGSV AVNNFANITF LHDDVWNLDH
210 220 230 240 250
SLFAPYDDAF ENFYIYQEWF EQVLQKKNAG FNVSITDLWG RALALKLVNP
260 270 280 290 300
LTGGANTTFS SVTNETWFQD GEFPFPIIIA DNVIEGETVI PLNDTVFEFT
310 320 330 340 350
PIEFGTWDTG VESFIPMEYT GTHLINGIPL NESCVRNFDN AGFLMGTSSN
360 370 380 390 400
VFSGILPATN ASLTASNNTF NNAVLSFLEM LAEDQLDVGL YPNPYQGYGN
410 420 430 440 450
ASNTTTTNPL EPYPIIELID GGSDSEGIPF WPLLHPQRDV DVIFAIDGGY
460 470 480 490 500
QSATSGWPDG SSLVSTYERV LATNSSGVRG FPYIPDTNTF LALGLNTHPT
510 520 530 540 550
FFGCDGRNTT AGNHTVNDDT PPLVVYFPNY PWTMYANVTT YTVQLEDTLS
560 570 580 590 600
SGMIENAAVA ATQNNSDSFA VCVACALVQR SLERKNMSTP SQCASCFNQY
610 620
CWNGTIASTT VTTYAPTVLS AKI
Length:623
Mass (Da):67,043
Last modified:September 22, 2009 - v3
Checksum:i7180BF849DBF0A69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB40176.3.
PIRiT40991.
RefSeqiNP_588308.2. NM_001023298.3.

Genome annotation databases

EnsemblFungiiSPCC1450.09c.1; SPCC1450.09c.1:pep; SPCC1450.09c.
GeneIDi2539134.
KEGGispo:SPCC1450.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB40176.3.
PIRiT40991.
RefSeqiNP_588308.2. NM_001023298.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275706. 32 interactors.
MINTiMINT-4717493.

Proteomic databases

PRIDEiQ9Y7N6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1450.09c.1; SPCC1450.09c.1:pep; SPCC1450.09c.
GeneIDi2539134.
KEGGispo:SPCC1450.09c.

Organism-specific databases

EuPathDBiFungiDB:SPCC1450.09c.
PomBaseiSPCC1450.09c.

Phylogenomic databases

HOGENOMiHOG000189547.
InParanoidiQ9Y7N6.
KOiK13333.
OMAiVCDDCNS.
OrthoDBiEOG092C2IZ9.
PhylomeDBiQ9Y7N6.

Miscellaneous databases

PROiQ9Y7N6.

Family and domain databases

InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamiPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTiSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiPS51210. PLA2C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPLB5_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7N6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: September 22, 2009
Last modified: October 5, 2016
This is version 92 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.