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Protein

ATP-dependent permease MDL1, mitochondrial

Gene

mdl1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi517 – 524ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent permease MDL1, mitochondrial
Alternative name(s):
ABC transporter mdl1
Gene namesi
Name:mdl1
ORF Names:SPBC9B6.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC9B6.09c.
PomBaseiSPBC9B6.09c. mdl1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei158 – 178HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei196 – 216HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei306 – 326HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei386 – 406HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei423 – 443HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 112MitochondrionSequence analysisAdd BLAST112
ChainiPRO_0000093470113 – 726ATP-dependent permease MDL1, mitochondrialAdd BLAST614

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi66N-linked (GlcNAc...)Sequence analysis1
Glycosylationi113N-linked (GlcNAc...)Sequence analysis1
Glycosylationi132N-linked (GlcNAc...)Sequence analysis1
Glycosylationi502N-linked (GlcNAc...)Sequence analysis1
Glycosylationi584N-linked (GlcNAc...)Sequence analysis1
Glycosylationi598N-linked (GlcNAc...)Sequence analysis1
Glycosylationi668N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ9Y7M7.
PRIDEiQ9Y7M7.

Interactioni

Protein-protein interaction databases

BioGridi277798. 4 interactors.
MINTiMINT-4717186.

Structurei

3D structure databases

ProteinModelPortaliQ9Y7M7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 447ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST290
Domaini482 – 719ABC transporterPROSITE-ProRule annotationAdd BLAST238

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ9Y7M7.
KOiK02021.
OMAiTFGMVLQ.
OrthoDBiEOG092C3H79.
PhylomeDBiQ9Y7M7.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y7M7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPIRFGLSR VPFAHCYNKR VIFRANYLVP LTWLKNNVAY KSTNTLLLPT
60 70 80 90 100
PNAEYYSTSK LSSQVNVSLN SLSQKASSGS KIYPFKNSFP LPFSRSILPI
110 120 130 140 150
RSLAFLKLCV RHNSTVPSKD EQAQDISKIN TNGTLQTPNK KVNVFRLFTL
160 170 180 190 200
ARGQGWNFFI AGSLLLVSSG VTMSIPYIVG KILDAGSSGD SSVTHIMGIP
210 220 230 240 250
SGTFYIGLLG LFFLGSACNF GRIITLRLLS ERIVSRLRAR LFAKCMSLDG
260 270 280 290 300
AFFDFHKHGD LISRLTTDSS IVGKSLSMYL SDGLRSSVSA IAGIGMMLYV
310 320 330 340 350
SMRLTGYMSL IVPPIALGAF FYGEYVRKLS RTTQDALGDL TRVSEEKLAN
360 370 380 390 400
VRTTQAFLGE RQEVNRYNDY IRNLFVLAKR EAFASGIFFG STGFLGNATV
410 420 430 440 450
IAILALGGRM VAAGDITVGQ LSSFLLYTVY AGGSIVGLSG CFTDIMKGLG
460 470 480 490 500
AASRLFELLD AKPKIAPTVG IPVPVTVGKA ILSFRNVGFA YPTRPSASIF
510 520 530 540 550
DNLSFDIHPG TNVAIVAPSG GGKSTISQLL LRFYAPSSGK ILADGVDIST
560 570 580 590 600
YNVHQWRSHF GLVGQEPVLF SGTIGENIAY GKSNASQEEI EDAAKRANCS
610 620 630 640 650
FVLSFPEKWS TQVGTRGLQL SGGQKQRIAI ARALLRNPAF LILDEATSAL
660 670 680 690 700
DGEAEVMVDK TIQSLMHNRS MTTITIAHKL ATIRRADQII VVGDGKVLEQ
710 720
GSFERLSRPG TNFYKLMRWQ LGKVEP
Length:726
Mass (Da):79,020
Last modified:November 1, 1999 - v1
Checksum:i203473D0B9585BCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB42370.1.
PIRiT40790.
RefSeqiNP_595751.1. NM_001021651.2.

Genome annotation databases

EnsemblFungiiSPBC9B6.09c.1; SPBC9B6.09c.1:pep; SPBC9B6.09c.
GeneIDi2541285.
KEGGispo:SPBC9B6.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB42370.1.
PIRiT40790.
RefSeqiNP_595751.1. NM_001021651.2.

3D structure databases

ProteinModelPortaliQ9Y7M7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277798. 4 interactors.
MINTiMINT-4717186.

Proteomic databases

MaxQBiQ9Y7M7.
PRIDEiQ9Y7M7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC9B6.09c.1; SPBC9B6.09c.1:pep; SPBC9B6.09c.
GeneIDi2541285.
KEGGispo:SPBC9B6.09c.

Organism-specific databases

EuPathDBiFungiDB:SPBC9B6.09c.
PomBaseiSPBC9B6.09c. mdl1.

Phylogenomic databases

InParanoidiQ9Y7M7.
KOiK02021.
OMAiTFGMVLQ.
OrthoDBiEOG092C3H79.
PhylomeDBiQ9Y7M7.

Miscellaneous databases

PROiQ9Y7M7.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMDL1_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7M7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: November 1, 1999
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.