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Protein

Probable U6 snRNA-associated Sm-like protein LSm3

Gene

lsm3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds specifically to the 3'-terminal U-tract of U6 snRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

ReactomeiR-SPO-430039. mRNA decay by 5' to 3' exoribonuclease.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable U6 snRNA-associated Sm-like protein LSm3
Gene namesi
Name:lsm3
ORF Names:SPBC9B6.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC9B6.05c.
PomBaseiSPBC9B6.05c. lsm3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001255621 – 93Probable U6 snRNA-associated Sm-like protein LSm3Add BLAST93

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei84Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9Y7M4.
PaxDbiQ9Y7M4.
PRIDEiQ9Y7M4.

PTM databases

iPTMnetiQ9Y7M4.

Interactioni

Subunit structurei

LSm subunits form a heteromer with a doughnut shape.By similarity

Protein-protein interaction databases

BioGridi276745. 7 interactors.
IntActiQ9Y7M4. 1 interactor.
STRINGi4896.SPBC9B6.05c.1.

Structurei

Secondary structure

193
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi12 – 15Combined sources4
Turni16 – 19Combined sources4
Beta strandi20 – 26Combined sources7
Turni27 – 29Combined sources3
Beta strandi30 – 39Combined sources10
Beta strandi45 – 54Combined sources10
Beta strandi71 – 80Combined sources10
Helixi82 – 84Combined sources3
Beta strandi85 – 89Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4EMGX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N1-93[»]
ProteinModelPortaliQ9Y7M4.
SMRiQ9Y7M4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the snRNP Sm proteins family.Curated

Phylogenomic databases

HOGENOMiHOG000223550.
InParanoidiQ9Y7M4.
KOiK12622.
OMAiGHMNLIL.
OrthoDBiEOG092C5VL3.
PhylomeDBiQ9Y7M4.

Family and domain databases

CDDicd01730. LSm3. 1 hit.
InterProiView protein in InterPro
IPR034105. Lsm3.
IPR001163. LSM_dom_euk/arc.
IPR010920. LSM_dom_sf.
PfamiView protein in Pfam
PF01423. LSM. 1 hit.
SMARTiView protein in SMART
SM00651. Sm. 1 hit.
SUPFAMiSSF50182. SSF50182. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Y7M4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESAQAVAEP LDLVRLSLDE IVYVKLRGDR ELNGRLHAYD EHLNMVLGDA
60 70 80 90
EEIVTIFDDE ETDKDKALKT IRKHYEMLFV RGDSVILIAP PRN
Length:93
Mass (Da):10,665
Last modified:May 1, 2000 - v2
Checksum:i86874A78670B1DCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB42366.2.
PIRiT40786.
RefSeqiNP_595747.1. NM_001021647.2.

Genome annotation databases

EnsemblFungiiSPBC9B6.05c.1; SPBC9B6.05c.1:pep; SPBC9B6.05c.
GeneIDi2540212.
KEGGispo:SPBC9B6.05c.

Similar proteinsi

Entry informationi

Entry nameiLSM3_SCHPO
AccessioniPrimary (citable) accession number: Q9Y7M4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: February 28, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome