Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9Y7I4 (ALG3_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase
EC=2.4.1.258
Alternative name(s):
Asparagine-linked glycosylation protein 3
Dol-P-Man-dependent alpha(1-3)-mannosyltransferase
Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
Gene names
Name:alg3
ORF Names:SPAC7D4.06c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc(2)-PP-Dol By similarity.

Catalytic activity

Dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->3)-D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the glycosyltransferase 58 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 406406Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase
PRO_0000327764

Regions

Transmembrane72 – 9221Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane186 – 20621Helical; Potential
Transmembrane214 – 23421Helical; Potential
Transmembrane261 – 28121Helical; Potential
Transmembrane313 – 33321Helical; Potential
Transmembrane349 – 36921Helical; Potential
Transmembrane376 – 39621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9Y7I4 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 039E40A16A9359C8

FASTA40646,992
        10         20         30         40         50         60 
MSSVETRNSF NPFRVLFDLG SYGWLHPSRL LLLEIPFVFA IISKVPYTEI DWIAYMEQVN 

        70         80         90        100        110        120 
SFLLGERDYK SLVGCTGPLV YPGGHVFLYT LLYYLTDGGT NIVRAQYIFA FVYWITTAIV 

       130        140        150        160        170        180 
GYLFKIVRAP FYIYVLLILS KRLHSIFILR LFNDGFNSLF SSLFILSSCK KKWVRASILL 

       190        200        210        220        230        240 
SVACSVKMSS LLYVPAYLVL LLQILGPKKT WMHIFVIIIV QILFSIPFLA YFWSYWTQAF 

       250        260        270        280        290        300 
DFGRAFDYKW TVNWRFIPRS IFESTSFSTS ILFLHVALLV AFTCKHWNKL SRATPFAMVN 

       310        320        330        340        350        360 
SMLTLKPLPK LQLATPNFIF TALATSNLIG ILCARSLHYQ FYAWFAWYSP YLCYQASFPA 

       370        380        390        400 
PIVIGLWMLQ EYAWNVFPST KLSSLIAVCV PLITILKLYT SDYRKP

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329670 Genomic DNA. Translation: CAB16723.2.
PIRT39084.
RefSeqNP_593853.1. NM_001019282.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9Y7I4.

Protein family/group databases

CAZyGT58. Glycosyltransferase Family 58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC7D4.06c.1; SPAC7D4.06c.1:pep; SPAC7D4.06c.
GeneID2542768.
GenomeReviewsGene locus alg3 in contig CU329670_GR.
KEGGspo:SPAC7D4.06c.
NMPDRfig|4896.1.peg.3823.

Organism-specific databases

GeneDB_SpombeSPAC7D4.06c.

Phylogenomic databases

eggNOGfuNOG07998.
GeneTreeEFGT00050000003598.
HOGENOMHBG525447.
OMAIHRVAYT.
OrthoDBEOG4MPN04.

Gene expression databases

ArrayExpressQ9Y7I4.

Family and domain databases

InterProIPR007873. Glycosyltransferase_ALG3.
[Graphical view]
KOK03845.
PANTHERPTHR12646. ALG3. 1 hit.
PfamPF05208. ALG3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALG3_SCHPO
AccessionPrimary (citable) accession number: Q9Y7I4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: November 1, 1999
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents