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Reviewed, UniProtKB/Swiss-Prot Q9Y7I4 (ALG3_SCHPO)

Last modified January 19, 2010. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
    EC=2.4.1.130
Alternative name(s):
    Dol-P-Man-dependent alpha(1-3)-mannosyltransferase
    Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
    Asparagine-linked glycosylation protein 3
Gene names
Name: alg3
ORF Names: SPAC7D4.06c
OrganismSchizosaccharomyces pombe (Fission yeast) [Complete proteome]
Taxonomic identifier4896 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

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Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc(2)-PP-Dol By similarity.

Catalytic activity

Transfers an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the glycosyltransferase 58 family.

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Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
Membrane
   DomainTransmembrane
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentintegral to endoplasmic reticulum membrane

Inferred by curator. Source: GeneDB_SPombe

   Molecular functiondolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity

Inferred by curator. Source: GeneDB_SPombe

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 406406Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
PRO_0000327764

Regions

Transmembrane72 – 9221 Potential
Transmembrane107 – 12721 Potential
Transmembrane129 – 14921 Potential
Transmembrane186 – 20621 Potential
Transmembrane214 – 23421 Potential
Transmembrane261 – 28121 Potential
Transmembrane313 – 33321 Potential
Transmembrane349 – 36921 Potential
Transmembrane376 – 39621 Potential

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Sequences

Sequence LengthMass (Da)Tools
Q9Y7I4-1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 039E40A16A9359C8

FASTA40646,992
        10         20         30         40         50         60 
MSSVETRNSF NPFRVLFDLG SYGWLHPSRL LLLEIPFVFA IISKVPYTEI DWIAYMEQVN 

        70         80         90        100        110        120 
SFLLGERDYK SLVGCTGPLV YPGGHVFLYT LLYYLTDGGT NIVRAQYIFA FVYWITTAIV 

       130        140        150        160        170        180 
GYLFKIVRAP FYIYVLLILS KRLHSIFILR LFNDGFNSLF SSLFILSSCK KKWVRASILL 

       190        200        210        220        230        240 
SVACSVKMSS LLYVPAYLVL LLQILGPKKT WMHIFVIIIV QILFSIPFLA YFWSYWTQAF 

       250        260        270        280        290        300 
DFGRAFDYKW TVNWRFIPRS IFESTSFSTS ILFLHVALLV AFTCKHWNKL SRATPFAMVN 

       310        320        330        340        350        360 
SMLTLKPLPK LQLATPNFIF TALATSNLIG ILCARSLHYQ FYAWFAWYSP YLCYQASFPA 

       370        380        390        400 
PIVIGLWMLQ EYAWNVFPST KLSSLIAVCV PLITILKLYT SDYRKP

« Hide

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References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 38366 / 972.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329670 Genomic DNA. Translation: CAB16723.2.
PIRT39084.
RefSeqNP_593853.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9Y7I4.

Protein family/group databases

CAZyGT58. Glycosyltransferase Family 58.

Genome annotation databases

GeneID2542768.
GenomeReviewsGene locus alg3 in contig CU329670_GR.
KEGGspo:SPAC7D4.06c.
NMPDRfig|4896.1.peg.3823.

Organism-specific databases

GeneDB_SpombeSPAC7D4.06c.

Phylogenomic databases

eggNOGfuNOG07998.
HOGENOMHBG525447.
OMALRLFNDC.
OrthoDBEOG9T4FBS.
PhylomeDBQ9Y7I4.

Enzyme and pathway databases

BRENDA2.4.1.130. 653.

Gene expression databases

ArrayExpressQ9Y7I4.

Family and domain databases

InterProIPR007873. Glycosyltransferase_ALG3.
[Graphical view]
PANTHERPTHR12646. ALG3. 1 hit.
PfamPF05208. ALG3. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameALG3_SCHPO
AccessionPrimary (citable) accession number: Q9Y7I4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: November 1, 1999
Last modified: January 19, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents