Invertase precursor - Kluyveromyces lactis (Yeast)

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Reviewed, UniProtKB/Swiss-Prot Q9Y746 (INV_KLULA)

Last modified November 3, 2009. Version 48. History...

Clusters with 100%, 90%, 50% identity |

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
    Invertase
    EC=3.2.1.26
Alternative name(s):
    Beta-fructofuranosidase
    Saccharase

Gene names

Name:	INV1
Ordered Locus Names:	KLLA0A10417g

Organism

Kluyveromyces lactis (Yeast) (Candida sphaerica) [Complete proteome]

Taxonomic identifier

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces

Protein attributes

Sequence length	609 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.
Sequence similarities	Belongs to the glycosyl hydrolase 32 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	beta-fructofuranosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

14

Potential

Chain

595

Invertase

PRO_0000033396

Regions

Region

4

Substrate binding By similarity

Region

2

Substrate binding By similarity

Region

2

Substrate binding By similarity

Sites

Active site

1

By similarity

Binding site

1

Substrate By similarity

Binding site

1

Substrate By similarity

Binding site

1

Substrate By similarity

Amino acid modifications

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Sequences

Sequence

Length

Mass (Da)

Tools

Q9Y746-1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 8C1F4F19D75B6319
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609

68,349

        10         20         30         40         50         60 
MLKLLSLMVP LASAAVIHRR DANISAIASE WNSTSNSSSS LSLNRPAVHY SPEEGWMNDP 

        70         80         90        100        110        120 
NGLWYDAKEE DWHIYYQYYP DAPHWGLPLT WGHAVSKDLT VWDEQGVAFG PEFETAGAFS 

       130        140        150        160        170        180 
GSMVIDYNNT SGFFNSSTDP RQRVVAIWTL DYSGSETQQL SYSHDGGYTF TEYSDNPVLD 

       190        200        210        220        230        240 
IDSDAFRDPK VFWYQGEDSE SEGNWVMTVA EADRFSVLIY SSPDLKNWTL ESNFSREGYL 

       250        260        270        280        290        300 
GYNYECPGLV KVPYVKNTTY ASAPGSNITS SGPLHPNSTV SFSNSSSIAW NASSVPLNIT 

       310        320        330        340        350        360 
LSNSTLVDET SQLEEVGYAW VMIVSFNPGS ILGGSGTEYF IGDFNGTHFE PLDKQTRFLD 

       370        380        390        400        410        420 
LGKDYYALQT FFNTPNEVDV LGIAWASNWQ YANQVPTDPW RSSMSLVRNF TITEYNINSN 

       430        440        450        460        470        480 
TTALVLNSQP VLDFTSLRKN GTSYTLENLT LNSSSHEVLE FEDPTGVFEF SLEYSVNFTG 

       490        500        510        520        530        540 
IHNWVFTDLS LYFQGDKDSD EYLRLGYEAN SKQFFLDRGH SNIPFVQENP FFTQRLSVSN 

       550        560        570        580        590        600 
PPSSNSSTFD VYGIVDRNII ELYFNNGTVT STNTFFFSTG NNIGSIIVKS GVDDVYEIES 


LKVNQFYVD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Glucose repression of the Kluyveromyces lactis invertase gene KIINV1 does not require Mig1p." Georis I., Cassart J.-P., Breunig K.D., Vandenhaute J. Mol. Gen. Genet. 261:862-870(1999) [PubMed: 10394924] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37.
[2]	"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases
	AF079370 Genomic DNA. Translation: AAD29850.1. CR382121 Genomic DNA. Translation: CAH03044.1.
RefSeq	XP_451456.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9Y746.
Genome annotation databases
GeneID	2896726.
GenomeReviews	Gene locus KLLA0A10417g in contig CR382121_GR.
KEGG	kla:KLLA0A10417g.
Phylogenomic databases
HOGENOM	Q9Y746.
OMA	AWASNWQ.
Enzyme and pathway databases
BRENDA	3.2.1.26. 74088.
Family and domain databases
InterPro	IPR001362. Glyco_hydro_32. IPR018053. Glyco_hydro_32_AS. IPR013189. Glyco_hydro_32_C. IPR013148. Glyco_hydro_32_N. [Graphical view]
Pfam	PF08244. Glyco_hydro_32C. 1 hit. PF00251. Glyco_hydro_32N. 1 hit. [Graphical view]
SMART	SM00640. Glyco_32. 1 hit. [Graphical view]
PROSITE	PS00609. GLYCOSYL_HYDROL_F32. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

INV_KLULA

Accession

Primary (citable) accession number: Q9Y746
Secondary accession number(s): Q6CX83

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	November 1, 1999
Last modified:	November 3, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents