Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9Y746 (INV_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Invertase
EC=3.2.1.26
Alternative name(s):
Beta-fructofuranosidase
Saccharase
Gene names
Name:INV1
Ordered Locus Names:KLLA0A10417g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Kluyveromyces ›

Protein attributes

Sequence length609 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.

Sequence similarities

Belongs to the glycosyl hydrolase 32 family.

Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionsucrose alpha-glucosidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1414 Potential
Chain15 – 609595Invertase
PRO_0000033396

Regions

Region56 – 594Substrate binding By similarity
Region119 – 1202Substrate binding By similarity
Region187 – 1882Substrate binding By similarity

Sites

Active site591 By similarity
Binding site771Substrate By similarity
Binding site2451Substrate By similarity
Binding site3891Substrate By similarity

Amino acid modifications

Glycosylation231N-linked (GlcNAc...) Potential
Glycosylation321N-linked (GlcNAc...) Potential
Glycosylation361N-linked (GlcNAc...) Potential
Glycosylation1281N-linked (GlcNAc...) Potential
Glycosylation1291N-linked (GlcNAc...) Potential
Glycosylation1351N-linked (GlcNAc...) Potential
Glycosylation2271N-linked (GlcNAc...) Potential
Glycosylation2331N-linked (GlcNAc...) Potential
Glycosylation2571N-linked (GlcNAc...) Potential
Glycosylation2671N-linked (GlcNAc...) Potential
Glycosylation2771N-linked (GlcNAc...) Potential
Glycosylation2841N-linked (GlcNAc...) Potential
Glycosylation2911N-linked (GlcNAc...) Potential
Glycosylation2981N-linked (GlcNAc...) Potential
Glycosylation3031N-linked (GlcNAc...) Potential
Glycosylation3451N-linked (GlcNAc...) Potential
Glycosylation4091N-linked (GlcNAc...) Potential
Glycosylation4201N-linked (GlcNAc...) Potential
Glycosylation4401N-linked (GlcNAc...) Potential
Glycosylation4481N-linked (GlcNAc...) Potential
Glycosylation4521N-linked (GlcNAc...) Potential
Glycosylation4771N-linked (GlcNAc...) Potential
Glycosylation5451N-linked (GlcNAc...) Potential
Glycosylation5661N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9Y746 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 8C1F4F19D75B6319

FASTA60968,349
        10         20         30         40         50         60 
MLKLLSLMVP LASAAVIHRR DANISAIASE WNSTSNSSSS LSLNRPAVHY SPEEGWMNDP 

        70         80         90        100        110        120 
NGLWYDAKEE DWHIYYQYYP DAPHWGLPLT WGHAVSKDLT VWDEQGVAFG PEFETAGAFS 

       130        140        150        160        170        180 
GSMVIDYNNT SGFFNSSTDP RQRVVAIWTL DYSGSETQQL SYSHDGGYTF TEYSDNPVLD 

       190        200        210        220        230        240 
IDSDAFRDPK VFWYQGEDSE SEGNWVMTVA EADRFSVLIY SSPDLKNWTL ESNFSREGYL 

       250        260        270        280        290        300 
GYNYECPGLV KVPYVKNTTY ASAPGSNITS SGPLHPNSTV SFSNSSSIAW NASSVPLNIT 

       310        320        330        340        350        360 
LSNSTLVDET SQLEEVGYAW VMIVSFNPGS ILGGSGTEYF IGDFNGTHFE PLDKQTRFLD 

       370        380        390        400        410        420 
LGKDYYALQT FFNTPNEVDV LGIAWASNWQ YANQVPTDPW RSSMSLVRNF TITEYNINSN 

       430        440        450        460        470        480 
TTALVLNSQP VLDFTSLRKN GTSYTLENLT LNSSSHEVLE FEDPTGVFEF SLEYSVNFTG 

       490        500        510        520        530        540 
IHNWVFTDLS LYFQGDKDSD EYLRLGYEAN SKQFFLDRGH SNIPFVQENP FFTQRLSVSN 

       550        560        570        580        590        600 
PPSSNSSTFD VYGIVDRNII ELYFNNGTVT STNTFFFSTG NNIGSIIVKS GVDDVYEIES 


LKVNQFYVD

« Hide

References

« Hide 'large scale' references
[1]"Glucose repression of the Kluyveromyces lactis invertase gene KIINV1 does not require Mig1p."
Georis I., Cassart J.-P., Breunig K.D., Vandenhaute J.
Mol. Gen. Genet. 261:862-870(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37.
[2]"Genome evolution in yeasts."
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. expand/collapse author list , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF079370 Genomic DNA. Translation: AAD29850.1.
CR382121 Genomic DNA. Translation: CAH03044.1.
RefSeqXP_451456.1. XM_451456.1.

3D structure databases

ProteinModelPortalQ9Y746.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2896726.
KEGGkla:KLLA0A10417g.

Phylogenomic databases

eggNOGCOG1621.
HOGENOMHOG000181424.
KOK01193.
OMANWQYTNQ.
OrthoDBEOG4V1B86.

Family and domain databases

InterProIPR008985. ConA-like_lec_gl_sf.
IPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PfamPF08244. Glyco_hydro_32C. 1 hit.
PF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTSM00640. Glyco_32. 1 hit.
[Graphical view]
SUPFAMSSF49899. ConA_like_lec_gl. 1 hit.
SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
PROSITEPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameINV_KLULA
AccessionPrimary (citable) accession number: Q9Y746
Secondary accession number(s): Q6CX83
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: November 1, 1999
Last modified: May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents