Reviewed, UniProtKB/Swiss-Prot Q9Y6Y1 (CMTA1_HUMAN)

Names and origin

Protein names

Recommended name:
    Calmodulin-binding transcription activator 1

Gene names

Name:	CAMTA1
Synonyms:	KIAA0833
ORF Names:	MSTP023

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1673 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Transcriptional activator. May act as a tumor suppressor. Ref.8 Ref.10
Subunit structure	May interact with calmodulin Potential.
Subcellular location	Nucleus Probable. Cytoplasm.
Tissue specificity	Detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen, heart and kidney. Detected in neuroblastic-type cultured neuroblastoma cells. Ref.8 Ref.10 Ref.9
Induction	Detected at low levels at interphase and in resting cells. Up-regulated during S-phase and mitosis. Levels decrease at the end of mitosis. Ref.9
Involvement in disease	Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma.
Sequence similarities	Belongs to the CAMTA family. Contains 3 ANK repeats. Contains 1 CG-1 DNA-binding domain. Contains 1 IPT/TIG domain. Contains 3 IQ domains.
Sequence caution	The sequence EAW71580.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Cytoplasm Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Domain	ANK repeat Repeat
Molecular function	Activator
PTM	Phosphoprotein
Technical term	3D-structure
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9Y6Y1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9Y6Y1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1458-1471: Missing.
     1653-1673: SPLVDHRLYKRSERIEKGQGT → RVKELKKAKELEDIQQHPLAM

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1673

1673

Calmodulin-binding transcription activator 1

PRO_0000235820

Regions

Domain

873 – 953

81

IPT/TIG

Repeat

1064 – 1093

30

ANK 1

Repeat

1109 – 1129

21

ANK 2

Repeat

1143 – 1172

30

ANK 3

Domain

1547 – 1576

30

IQ 1

Domain

1577 – 1599

23

IQ 2

Domain

1600 – 1622

23

IQ 3

DNA binding

63 – 188

126

CG-1

Motif

112 – 119

8

Nuclear localization signal Potential

Compositional bias

499 – 502

4

Poly-Gly

Compositional bias

1038 – 1041

4

Poly-Val

Amino acid modifications

Modified residue

117

1

Phosphotyrosine Ref.11

Natural variations

Alternative sequence

1458 – 1471

14

Missing in isoform 2.

VSP_035936

Alternative sequence

1653 – 1673

21

SPLVD…KGQGT → RVKELKKAKELEDIQQHPLA M in isoform 2.

VSP_035937

Natural variant

1177

1

N → K: dbSNP rs41278952. Ref.13

VAR_047824

Natural variant

1218

1

N → T: dbSNP rs41278954. Ref.13

VAR_047825

Natural variant

1336

1

T → I Ref.13

VAR_047826

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

1673

Helix Strand Turn

Details...

Beta strand

875 – 877

3

Beta strand

879 – 881

3

Beta strand

888 – 894

7

Beta strand

902 – 906

5

Beta strand

909 – 912

4

Beta strand

914 – 917

4

Beta strand

920 – 924

5

Beta strand

930 – 939

10

Beta strand

948 – 952

5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 16, 2006. Version 4. Checksum: 008AA6A906374C00	FASTA	1,673	183,672
	10 20 30 40 50 60 MWRAEGKWLP KTSRKSVSQS VFCGTSTYCV LNTVPPIEDD HGNSNSSHVK IFLPKKLLEC 70 80 90 100 110 120 LPKCSSLPKE RHRWNTNEEI AAYLITFEKH EEWLTTSPKT RPQNGSMILY NRKKVKYRKD 130 140 150 160 170 180 GYCWKKRKDG KTTREDHMKL KVQGVECLYG CYVHSSIIPT FHRRCYWLLQ NPDIVLVHYL 190 200 210 220 230 240 NVPAIEDCGK PCGPILCSIN TDKKEWAKWT KEELIGQLKP MFHGIKWTCS NGNSSSGFSV 250 260 270 280 290 300 EQLVQQILDS HQTKPQPRTH NCLCTGSLGA GGSVHHKCNS AKHRIISPKV EPRTGGYGSH 310 320 330 340 350 360 SEVQHNDVSE GKHEHSHSKG SSREKRNGKV AKPVLLHQSS TEVSSTNQVE VPDTTQSSPV 370 380 390 400 410 420 SISSGLNSDP DMVDSPVVTG VSGMAVASVM GSLSQSATVF MSEVTNEAVY TMSPTAGPNH 430 440 450 460 470 480 HLLSPDASQG LVLAVSSDGH KFAFPTTGSS ESLSMLPTNV SEELVLSTTL DGGRKIPETT 490 500 510 520 530 540 MNFDPDCFLN NPKQGQTYGG GGLKAEMVSS NIRHSPPGER SFSFTTVLTK EIKTEDTSFE 550 560 570 580 590 600 QQMAKEAYSS SAAAVAASSL TLTAGSSLLP SGGGLSPSTT LEQMDFSAID SNKDYTSSFS 610 620 630 640 650 660 QTGHSPHIHQ TPSPSFFLQD ASKPLPVEQN THSSLSDSGG TFVMPTVKTE ASSQTSSCSG 670 680 690 700 710 720 HVETRIESTS SLHLMQFQAN FQAMTAEGEV TMETSQAAEG SEVLLKSGEL QACSSEHYLQ 730 740 750 760 770 780 PETNGVIRSA GGVPILPGNV VQGLYPVAQP SLGNASNMEL SLDHFDISFS NQFSDLINDF 790 800 810 820 830 840 ISVEGGSSTI YGHQLVSGDS TALSQSEDGA RAPFTQAEMC LPCCSPQQGS LQLSSSEGGA 850 860 870 880 890 900 STMAYMHVAE VVSAASAQGT LGMLQQSGRV FMVTDYSPEW SYPEGGVKVL ITGPWQEASN 910 920 930 940 950 960 NYSCLFDQIS VPASLIQPGV LRCYCPAHDT GLVTLQVAFN NQIISNSVVF EYKARALPTL 970 980 990 1000 1010 1020 PSSQHDWLSL DDNQFRMSIL ERLEQMERRM AEMTGSQQHK QASGGGSSGG GSGSGNGGSQ 1030 1040 1050 1060 1070 1080 AQCASGTGAL GSCFESRVVV VCEKMMSRAC WAKSKHLIHS KTFRGMTLLH LAAAQGYATL 1090 1100 1110 1120 1130 1140 IQTLIKWRTK HADSIDLELE VDPLNVDHFS CTPLMWACAL GHLEAAVVLY KWDRRAISIP 1150 1160 1170 1180 1190 1200 DSLGRLPLGI ARSRGHVKLA ECLEHLQRDE QAQLGQNPRI HCPASEEPST ESWMAQWHSE 1210 1220 1230 1240 1250 1260 AISSPEIPKG VTVIASTNPE LRRPRSEPSN YYSSESHKDY PAPKKHKLNP EYFQTRQEKL 1270 1280 1290 1300 1310 1320 LPTALSLEEP NIRKQSPSSK QSVPETLSPS EGVRDFSREL SPPTPETAAF QASGSQPVGK 1330 1340 1350 1360 1370 1380 WNSKDLYIGV STVQVTGNPK GTSVGKEAAP SQVRPREPMS VLMMANREVV NTELGSYRDS 1390 1400 1410 1420 1430 1440 AENEECGQPM DDIQVNMMTL AEHIIEATPD RIKQENFVPM ESSGLERTDP ATISSTMSWL 1450 1460 1470 1480 1490 1500 ASYLADADCL PSAAQIRSAY NEPLTPSSNT SLSPVGSPVS EIAFEKPNLP SAADWSEFLS 1510 1520 1530 1540 1550 1560 ASTSEKVENE FAQLTLSDHE QRELYEAARL VQTAFRKYKG RPLREQQEVA AAVIQRCYRK 1570 1580 1590 1600 1610 1620 YKQYALYKKM TQAAILIQSK FRSYYEQKKF QQSRRAAVLI QKYYRSYKKC GKRRQARRTA 1630 1640 1650 1660 1670 VIVQQKLRSS LLTKKQDQAA RKIMRFLRRC RHSPLVDHRL YKRSERIEKG QGT
	Isoform 2. Checksum: E03DDA09EEB25873	FASTA	1,659	182,257
	10 20 30 40 50 60 MWRAEGKWLP KTSRKSVSQS VFCGTSTYCV LNTVPPIEDD HGNSNSSHVK IFLPKKLLEC 70 80 90 100 110 120 LPKCSSLPKE RHRWNTNEEI AAYLITFEKH EEWLTTSPKT RPQNGSMILY NRKKVKYRKD 130 140 150 160 170 180 GYCWKKRKDG KTTREDHMKL KVQGVECLYG CYVHSSIIPT FHRRCYWLLQ NPDIVLVHYL 190 200 210 220 230 240 NVPAIEDCGK PCGPILCSIN TDKKEWAKWT KEELIGQLKP MFHGIKWTCS NGNSSSGFSV 250 260 270 280 290 300 EQLVQQILDS HQTKPQPRTH NCLCTGSLGA GGSVHHKCNS AKHRIISPKV EPRTGGYGSH 310 320 330 340 350 360 SEVQHNDVSE GKHEHSHSKG SSREKRNGKV AKPVLLHQSS TEVSSTNQVE VPDTTQSSPV 370 380 390 400 410 420 SISSGLNSDP DMVDSPVVTG VSGMAVASVM GSLSQSATVF MSEVTNEAVY TMSPTAGPNH 430 440 450 460 470 480 HLLSPDASQG LVLAVSSDGH KFAFPTTGSS ESLSMLPTNV SEELVLSTTL DGGRKIPETT 490 500 510 520 530 540 MNFDPDCFLN NPKQGQTYGG GGLKAEMVSS NIRHSPPGER SFSFTTVLTK EIKTEDTSFE 550 560 570 580 590 600 QQMAKEAYSS SAAAVAASSL TLTAGSSLLP SGGGLSPSTT LEQMDFSAID SNKDYTSSFS 610 620 630 640 650 660 QTGHSPHIHQ TPSPSFFLQD ASKPLPVEQN THSSLSDSGG TFVMPTVKTE ASSQTSSCSG 670 680 690 700 710 720 HVETRIESTS SLHLMQFQAN FQAMTAEGEV TMETSQAAEG SEVLLKSGEL QACSSEHYLQ 730 740 750 760 770 780 PETNGVIRSA GGVPILPGNV VQGLYPVAQP SLGNASNMEL SLDHFDISFS NQFSDLINDF 790 800 810 820 830 840 ISVEGGSSTI YGHQLVSGDS TALSQSEDGA RAPFTQAEMC LPCCSPQQGS LQLSSSEGGA 850 860 870 880 890 900 STMAYMHVAE VVSAASAQGT LGMLQQSGRV FMVTDYSPEW SYPEGGVKVL ITGPWQEASN 910 920 930 940 950 960 NYSCLFDQIS VPASLIQPGV LRCYCPAHDT GLVTLQVAFN NQIISNSVVF EYKARALPTL 970 980 990 1000 1010 1020 PSSQHDWLSL DDNQFRMSIL ERLEQMERRM AEMTGSQQHK QASGGGSSGG GSGSGNGGSQ 1030 1040 1050 1060 1070 1080 AQCASGTGAL GSCFESRVVV VCEKMMSRAC WAKSKHLIHS KTFRGMTLLH LAAAQGYATL 1090 1100 1110 1120 1130 1140 IQTLIKWRTK HADSIDLELE VDPLNVDHFS CTPLMWACAL GHLEAAVVLY KWDRRAISIP 1150 1160 1170 1180 1190 1200 DSLGRLPLGI ARSRGHVKLA ECLEHLQRDE QAQLGQNPRI HCPASEEPST ESWMAQWHSE 1210 1220 1230 1240 1250 1260 AISSPEIPKG VTVIASTNPE LRRPRSEPSN YYSSESHKDY PAPKKHKLNP EYFQTRQEKL 1270 1280 1290 1300 1310 1320 LPTALSLEEP NIRKQSPSSK QSVPETLSPS EGVRDFSREL SPPTPETAAF QASGSQPVGK 1330 1340 1350 1360 1370 1380 WNSKDLYIGV STVQVTGNPK GTSVGKEAAP SQVRPREPMS VLMMANREVV NTELGSYRDS 1390 1400 1410 1420 1430 1440 AENEECGQPM DDIQVNMMTL AEHIIEATPD RIKQENFVPM ESSGLERTDP ATISSTMSWL 1450 1460 1470 1480 1490 1500 ASYLADADCL PSAAQIRLSP VGSPVSEIAF EKPNLPSAAD WSEFLSASTS EKVENEFAQL 1510 1520 1530 1540 1550 1560 TLSDHEQREL YEAARLVQTA FRKYKGRPLR EQQEVAAAVI QRCYRKYKQY ALYKKMTQAA 1570 1580 1590 1600 1610 1620 ILIQSKFRSY YEQKKFQQSR RAAVLIQKYY RSYKKCGKRR QARRTAVIVQ QKLRSSLLTK 1630 1640 1650 KQDQAARKIM RFLRRCRHRV KELKKAKELE DIQQHPLAM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 5:355-364(1998) [PubMed: 10048485] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Brain.
[2]	"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T. DNA Res. 9:99-106(2002) [PubMed: 12168954] [Abstract] Cited for: SEQUENCE REVISION.
[3]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed: 16710414] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[6]	Xu Y.Y., Sun L.Z., Wu Q.Y., Liu Y.Q., Liu B., Zhao B., Wang X.Y., Song L., Ye J., Sheng H., Gao Y., Zhang C.L., Zhang J., Wei Y.J., Sun Y.H., Jiang Y.X., Zhao X.W., Liu S. , Liu L.S., Ding J.F., Gao R.L., Qiang B.Q., Yuan J.G., Liew C.C., Zhao M.S., Hui R.T. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1422-1673 (ISOFORM 2). Tissue: Heart.
[7]	Li H., Li S., Yu R., Shen C., Zhou G., Ke R., Lin L., Yang S. Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1437-1673 (ISOFORM 2).
[8]	"A novel family of calmodulin-binding transcription activators in multicellular organisms." Bouche N., Scharlat A., Snedden W., Bouchez D., Fromm H. J. Biol. Chem. 277:21851-21861(2002) [PubMed: 11925432] [Abstract] Cited for: FUNCTION, SUBUNIT, TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
[9]	"Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells." Nakatani K., Nishioka J., Itakura T., Nakanishi Y., Horinouchi J., Abe Y., Wada H., Nobori T. Int. J. Oncol. 24:1407-1412(2004) [PubMed: 15138581] [Abstract] Cited for: INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[10]	"Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene." Barbashina V., Salazar P., Holland E.C., Rosenblum M.K., Ladanyi M. Clin. Cancer Res. 11:1119-1128(2005) [PubMed: 15709179] [Abstract] Cited for: FUNCTION, INVOLVEMENT IN OLIGODENDROGLIOMA AND ASTROCYTOMA, TISSUE SPECIFICITY.
[11]	"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J., Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L., Mitchell J., Wetzel R., Macneill J., Ren J.M. , Yuan J., Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X., Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J. Cell 131:1190-1203(2007) [PubMed: 18083107] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-117, MASS SPECTROMETRY.
[12]	"Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1)." RIKEN structural genomics initiative (RSGI) Submitted (DEC-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 872-953.
[13]	"Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma." Henrich K.-O., Claas A., Praml C., Benner A., Mollenhauer J., Poustka A., Schwab M., Westermann F. Eur. J. Cancer 43:607-616(2007) [PubMed: 17222547] [Abstract] Cited for: VARIANTS LYS-1177; THR-1218 AND ILE-1336.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AB020640 mRNA. Translation: BAA74856.3. Different initiation.
AL590128 , AL359881, AL365194, AL596210, Z97635, Z98052, Z98884 Genomic DNA. Translation: CAH72347.1.
AL359881 , AL365194, AL590128, AL596210, Z97635, Z98884, Z98052 Genomic DNA. Translation: CAH72663.1.
AL596210 , AL359881, AL365194, AL590128, Z97635, Z98052, Z98884 Genomic DNA. Translation: CAI17064.1.
Z97635 , Z98884, Z98052, AL596210, AL590128, AL365194, AL359881 Genomic DNA. Translation: CAI20961.1.
Z98884 , Z98052, Z97635, AL359881, AL365194, AL596210, AL590128 Genomic DNA. Translation: CAI21433.1.
Z98052 , Z98884, Z97635, AL359881, AL596210, AL590128, AL365194 Genomic DNA. Translation: CAI21596.1.
AL365194 , AL359881, AL590128, AL596210, Z97635, Z98052, Z98884 Genomic DNA. Translation: CAI21790.1.
CH471130 Genomic DNA. Translation: EAW71580.1. Sequence problems.
BC151835 mRNA. Translation: AAI51836.1.
AF111804 mRNA. Translation: AAL39006.1. Different initiation.
AY349360 mRNA. Translation: AAQ56724.1.

IPI

IPI00166031.
IPI00915425.

RefSeq

NP_056030.1.

UniGene

Hs.397705

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2CXK	X-ray	1.85	A/B/C/D/E	872-953	[»]

ModBase

Search...

PTM databases

PhosphoSite

Q9Y6Y1.

Proteomic databases

PRIDE

Q9Y6Y1.

Genome annotation databases

Ensembl

ENSG00000171735. Homo sapiens. [Contig view]

GeneID

23261.

KEGG

hsa:23261.

Organism-specific databases

GeneCards

GC01P006779.

H-InvDB

HIX0000090.

HGNC

HGNC:18806. CAMTA1.

MIM

611501. gene.

PharmGKB

PA38688.

HUGE

Search...

GenAtlas

Search...

Phylogenomic databases

HOGENOM

Q9Y6Y1.

HOVERGEN

Q9Y6Y1.

OMA

Q9Y6Y1. QPRTHNC.

Gene expression databases

ArrayExpress

Q9Y6Y1.

Bgee

Q9Y6Y1.

CleanEx

HS_CAMTA1.

GermOnline

ENSG00000171735. Homo sapiens.

Family and domain databases

InterPro

IPR002110. ANK.
IPR005559. CG-1.
IPR002909. IPT_TIG_rcpt.
IPR000048. IQ_CaM_bd_region.
[Graphical view]

Gene3D

G3DSA:1.25.40.20. ANK. 1 hit.

Pfam

PF00023. Ank. 2 hits.
PF03859. CG-1. 1 hit.
PF00612. IQ. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]

SMART

SM00248. ANK. 2 hits.
SM00015. IQ. 3 hits.
[Graphical view]

PROSITE

PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS51437. CG_1. 1 hit.
PS50096. IQ. 1 hit.
[Graphical view]

ProtoNet

Search...

Other Resources

NextBio

44996.

SOURCE

Search...

Entry information

Entry name

CMTA1_HUMAN

Accession

Primary (citable) accession number: Q9Y6Y1
Secondary accession number(s): A7MBM4 , Q5VUE1, Q6V701, Q8WYI3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	June 16, 2009
This is version 63 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)