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Protein

Testis-expressed protein 264

Gene

TEX264

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-HSA-114608 Platelet degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 264
Alternative name(s):
Putative secreted protein Zsig11
Gene namesi
Name:TEX264
Synonyms:ZSIG11
ORF Names:UNQ337/PRO536
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000164081.12
HGNCiHGNC:30247 TEX264
neXtProtiNX_Q9Y6I9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164081
PharmGKBiPA134875244

Polymorphism and mutation databases

BioMutaiTEX264
DMDMi22002027

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_000002260133 – 313Testis-expressed protein 264Add BLAST281

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi45N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei239PhosphoserineCombined sources1
Modified residuei244PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ9Y6I9
MaxQBiQ9Y6I9
PaxDbiQ9Y6I9
PeptideAtlasiQ9Y6I9
PRIDEiQ9Y6I9
ProteomicsDBi86698
TopDownProteomicsiQ9Y6I9

PTM databases

iPTMnetiQ9Y6I9
PhosphoSitePlusiQ9Y6I9
SwissPalmiQ9Y6I9

Expressioni

Gene expression databases

BgeeiENSG00000164081
CleanExiHS_TEX264
ExpressionAtlasiQ9Y6I9 baseline and differential
GenevisibleiQ9Y6I9 HS

Organism-specific databases

HPAiCAB005002
HPA017739

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TMEM79Q9BSE25EBI-10329860,EBI-8649725

Protein-protein interaction databases

BioGridi119503, 45 interactors
IntActiQ9Y6I9, 8 interactors
STRINGi9606.ENSP00000340969

Structurei

3D structure databases

ProteinModelPortaliQ9Y6I9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IJI6 Eukaryota
ENOG4111NB9 LUCA
GeneTreeiENSGT00390000016901
HOGENOMiHOG000065678
HOVERGENiHBG059535
InParanoidiQ9Y6I9
OMAiAYKFHVG
OrthoDBiEOG091G0NIA
PhylomeDBiQ9Y6I9
TreeFamiTF328465

Family and domain databases

Gene3Di3.20.80.10, 1 hit
InterProiView protein in InterPro
IPR011256 Reg_factor_effector_dom_sf
SUPFAMiSSF55136 SSF55136, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y6I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLLLLGLI GGLTLLLLLT LLAFAGYSGL LAGVEVSAGS PPIRNVTVAY
60 70 80 90 100
KFHMGLYGET GRLFTESCSI SPKLRSIAVY YDNPHMVPPD KCRCAVGSIL
110 120 130 140 150
SEGEESPSPE LIDLYQKFGF KVFSFPAPSH VVTATFPYTT ILSIWLATRR
160 170 180 190 200
VHPALDTYIK ERKLCAYPRL EIYQEDQIHF MCPLARQGDF YVPEMKETEW
210 220 230 240 250
KWRGLVEAID TQVDGTGADT MSDTSSVSLE VSPGSRETSA ATLSPGASSR
260 270 280 290 300
GWDDGDTRSE HSYSESGASG SSFEELDLEG EGPLGESRLD PGTEPLGTTK
310
WLWEPTAPEK GKE
Length:313
Mass (Da):34,189
Last modified:November 1, 1999 - v1
Checksum:i6159011A220F1C67
GO

Sequence cautioni

The sequence AAD52584 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_061718292G → E. Corresponds to variant dbSNP:rs11553574Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF072733 mRNA Translation: AAD22397.1
AY358972 mRNA Translation: AAQ89331.1
AK023997 mRNA Translation: BAG51249.1
CH471055 Genomic DNA Translation: EAW65146.1
BC008742 mRNA Translation: AAH08742.1
AF172327 mRNA Translation: AAD52584.1 Different initiation.
CCDSiCCDS2833.1
RefSeqiNP_001123356.1, NM_001129884.2
NP_001230654.1, NM_001243725.1
NP_001230655.1, NM_001243726.1
NP_001230656.1, NM_001243727.2
NP_001265124.1, NM_001278195.1
NP_057010.1, NM_015926.5
XP_006713258.1, XM_006713195.3
XP_006713260.1, XM_006713197.3
XP_011532107.1, XM_011533805.2
UniGeneiHs.517864
Hs.733397

Genome annotation databases

EnsembliENST00000341333; ENSP00000340969; ENSG00000164081
ENST00000395057; ENSP00000378497; ENSG00000164081
ENST00000415259; ENSP00000396628; ENSG00000164081
ENST00000416589; ENSP00000398802; ENSG00000164081
ENST00000457573; ENSP00000408186; ENSG00000164081
ENST00000611400; ENSP00000477946; ENSG00000164081
GeneIDi51368
KEGGihsa:51368
UCSCiuc003dbk.6 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiTX264_HUMAN
AccessioniPrimary (citable) accession number: Q9Y6I9
Secondary accession number(s): B3KN87, Q9UKD7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: November 1, 1999
Last modified: June 20, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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