##gff-version 3
Q9Y6H5	UniProtKB	Chain	1	919	.	.	.	ID=PRO_0000067068;Note=Synphilin-1	
Q9Y6H5	UniProtKB	Repeat	349	380	.	.	.	Note=ANK 1	
Q9Y6H5	UniProtKB	Repeat	384	413	.	.	.	Note=ANK 2	
Q9Y6H5	UniProtKB	Repeat	419	448	.	.	.	Note=ANK 3	
Q9Y6H5	UniProtKB	Repeat	456	485	.	.	.	Note=ANK 4	
Q9Y6H5	UniProtKB	Repeat	603	632	.	.	.	Note=ANK 5	
Q9Y6H5	UniProtKB	Repeat	699	729	.	.	.	Note=ANK 6	
Q9Y6H5	UniProtKB	Region	80	99	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Region	108	140	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Region	287	313	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Region	549	615	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Region	666	713	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Region	728	919	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Coiled coil	515	552	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9Y6H5	UniProtKB	Compositional bias	287	309	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Compositional bias	549	573	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Compositional bias	680	702	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Compositional bias	742	815	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Compositional bias	831	845	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Compositional bias	868	919	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y6H5	UniProtKB	Alternative sequence	1	366	.	.	.	ID=VSP_038839;Note=In isoform 2 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:16595633;Dbxref=PMID:15489334,PMID:16595633	
Q9Y6H5	UniProtKB	Alternative sequence	19	19	.	.	.	ID=VSP_038840;Note=In isoform 3 and isoform 6. S->SDNRSQGNRLQKLGLEDTDREDAMGFGSHRAKLTVVAALGACHCPENE;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|Ref.4;Dbxref=PMID:15489334	
Q9Y6H5	UniProtKB	Alternative sequence	335	394	.	.	.	ID=VSP_038841;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4	
Q9Y6H5	UniProtKB	Alternative sequence	367	394	.	.	.	ID=VSP_038842;Note=In isoform 2 and isoform 5. QHLTSLMGEDCLNERNTEKLTPAGLAIK->MTYLIQSHHSRRSQNCAEDVIRKTKTDQ;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:16595633;Dbxref=PMID:15489334,PMID:16595633	
Q9Y6H5	UniProtKB	Alternative sequence	476	541	.	.	.	ID=VSP_038843;Note=In isoform 6. LVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQN->RLKIQGTWNGSETCLFTHHFSSYPPISSGLQCQGQEGVLFIPDQVGAATNKQVLFQNQLPETKSSY;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4	
Q9Y6H5	UniProtKB	Alternative sequence	542	919	.	.	.	ID=VSP_038844;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4	
Q9Y6H5	UniProtKB	Alternative sequence	919	919	.	.	.	ID=VSP_038845;Note=In isoform 2 and isoform 3. A->EMYSSCINLSSNMLIEEHLCNDTRHNDINRKMKKSYSIKHIAEPESKELFL;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:16595633;Dbxref=PMID:15489334,PMID:16595633	
Q9Y6H5	UniProtKB	Natural variant	44	44	.	.	.	ID=VAR_065358;Note=V->A;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10319874,ECO:0000269|PubMed:18366718,ECO:0000269|Ref.4;Dbxref=dbSNP:rs56285021,PMID:10319874,PMID:18366718	
Q9Y6H5	UniProtKB	Natural variant	235	235	.	.	.	ID=VAR_048312;Note=E->G;Dbxref=dbSNP:rs6867105	
Q9Y6H5	UniProtKB	Natural variant	621	621	.	.	.	ID=VAR_025667;Note=Found in patients with symptoms of Parkinson disease%3B uncertain significance%3B reduced number of cytoplasmic inclusions in cells expressing C-621 compared with cells expressing wild-type (wt) protein when subjected to proteasomal inhibition%3B C-621 transfected cells are more susceptible to staurosporine-induced cell death than cells expressing wt protein. R->C;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12761037,ECO:0000269|PubMed:18366718;Dbxref=dbSNP:rs28937592,PMID:12761037,PMID:18366718	
Q9Y6H5	UniProtKB	Natural variant	706	706	.	.	.	ID=VAR_065359;Note=E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18366718;Dbxref=PMID:18366718	
Q9Y6H5	UniProtKB	Mutagenesis	79	79	.	.	.	Note=Decreases interaction with SIAH1 and formation of cytoplasmic inclusion bodies%3B when associated with N-81. V->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15064394;Dbxref=PMID:15064394	
Q9Y6H5	UniProtKB	Mutagenesis	81	81	.	.	.	Note=Decreases interaction with SIAH1 and formation of cytoplasmic inclusion bodies%3B when associated with N-79. P->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15064394;Dbxref=PMID:15064394	
Q9Y6H5	UniProtKB	Sequence conflict	188	188	.	.	.	Note=S->F;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Sequence conflict	614	614	.	.	.	Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Sequence conflict	696	696	.	.	.	Note=A->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Sequence conflict	712	712	.	.	.	Note=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Sequence conflict	801	801	.	.	.	Note=S->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Sequence conflict	919	919	.	.	.	Note=A->E;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Y6H5	UniProtKB	Helix	512	554	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2KES