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Q9Y6B7

- AP4B1_HUMAN

UniProt

Q9Y6B7 - AP4B1_HUMAN

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Protein

AP-4 complex subunit beta-1

Gene

AP4B1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

GO - Molecular functioni

  1. protein transporter activity Source: InterPro
  2. transporter activity Source: ProtInc

GO - Biological processi

  1. intracellular protein transport Source: InterPro
  2. vesicle-mediated transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiREACT_19400. Golgi Associated Vesicle Biogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
AP-4 complex subunit beta-1
Alternative name(s):
AP-4 adaptor complex subunit beta
Adaptor-related protein complex 4 subunit beta-1
Beta subunit of AP-4
Beta4-adaptin
Gene namesi
Name:AP4B1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:572. AP4B1.

Subcellular locationi

Golgi apparatustrans-Golgi network 1 Publication. Membranecoated pit By similarity
Note: Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.

GO - Cellular componenti

  1. clathrin adaptor complex Source: InterPro
  2. coated pit Source: UniProtKB-KW
  3. trans-Golgi network Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Coated pit, Golgi apparatus, Membrane

Pathology & Biotechi

Involvement in diseasei

Cerebral palsy, spastic quadriplegic 5 (CPSQ5) [MIM:614066]: A neurodevelopmental disorder characterized by neonatal hypotonia that progresses to hypertonia and spasticity, and severe mental retardation with poor or absent speech development.1 Publication
Note: The disease is caused by mutations affecting the gene represented in this entry.

Organism-specific databases

MIMi614066. phenotype.
Orphaneti280763. Severe intellectual disability and progressive spastic paraplegia.
PharmGKBiPA24864.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 739739AP-4 complex subunit beta-1PRO_0000193750Add
BLAST

Proteomic databases

MaxQBiQ9Y6B7.
PaxDbiQ9Y6B7.
PRIDEiQ9Y6B7.

PTM databases

PhosphoSiteiQ9Y6B7.

Expressioni

Tissue specificityi

Widely expressed.

Gene expression databases

BgeeiQ9Y6B7.
CleanExiHS_AP4B1.
ExpressionAtlasiQ9Y6B7. baseline and differential.
GenevestigatoriQ9Y6B7.

Organism-specific databases

HPAiHPA028162.
HPA028399.
HPA028652.

Interactioni

Subunit structurei

Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1 and beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1). Interacts with ENTHD2; this interaction requires the presence of a functional AP-4 complex.1 Publication

Protein-protein interaction databases

BioGridi115943. 5 interactions.
DIPiDIP-24209N.
IntActiQ9Y6B7. 1 interaction.
STRINGi9606.ENSP00000256658.

Structurei

Secondary structure

1
739
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi628 – 63710Combined sources
Beta strandi641 – 6477Combined sources
Helixi654 – 66310Combined sources
Beta strandi667 – 6715Combined sources
Beta strandi677 – 68711Combined sources
Beta strandi692 – 6998Combined sources
Beta strandi701 – 7033Combined sources
Beta strandi705 – 71410Combined sources
Helixi717 – 73519Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2MJ7NMR-A610-739[»]
ProteinModelPortaliQ9Y6B7.
SMRiQ9Y6B7. Positions 9-576, 609-739.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG5096.
GeneTreeiENSGT00530000063138.
HOGENOMiHOG000294128.
HOVERGENiHBG050521.
InParanoidiQ9Y6B7.
KOiK12401.
OMAiRPWKAYL.
PhylomeDBiQ9Y6B7.
TreeFamiTF354235.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.310.10. 1 hit.
InterProiIPR026739. AP_beta.
IPR016342. AP_complex_bsu_1_2_4.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR015151. B-adaptin_app_sub_C.
IPR012295. Beta2_adaptin/TBP_C_dom.
IPR002553. Clathrin/coatomer_adapt-like_N.
[Graphical view]
PANTHERiPTHR11134. PTHR11134. 1 hit.
PfamiPF01602. Adaptin_N. 1 hit.
PF09066. B2-adapt-app_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002291. AP_complex_beta. 1 hit.
SMARTiSM01020. B2-adapt-app_C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9Y6B7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPYLGSEDVV KELKKALCNP HIQADRLRYR NVIQRVIRYM TQGLDMSGVF
60 70 80 90 100
MEMVKASATV DIVQKKLVYL YMCTYAPLKP DLALLAINTL CKDCSDPNPM
110 120 130 140 150
VRGLALRSMC SLRMPGVQEY IQQPILNGLR DKASYVRRVA VLGCAKMHNL
160 170 180 190 200
HGDSEVDGAL VNELYSLLRD QDPIVVVNCL RSLEEILKQE GGVVINKPIA
210 220 230 240 250
HHLLNRMSKL DQWGQAEVLN FLLRYQPRSE EELFDILNLL DSFLKSSSPG
260 270 280 290 300
VVMGATKLFL ILAKMFPHVQ TDVLVRVKGP LLAACSSESR ELCFVALCHV
310 320 330 340 350
RQILHSLPGH FSSHYKKFFC SYSEPHYIKL QKVEVLCELV NDENVQQVLE
360 370 380 390 400
ELRGYCTDVS ADFAQAAIFA IGGIARTYTD QCVQILTELL GLRQEHITTV
410 420 430 440 450
VVQTFRDLVW LCPQCTEAVC QALPGCEENI QDSEGKQALI WLLGVHGERI
460 470 480 490 500
PNAPYVLEDF VENVKSETFP AVKMELLTAL LRLFLSRPAE CQDMLGRLLY
510 520 530 540 550
YCIEEEKDMA VRDRGLFYYR LLLVGIDEVK RILCSPKSDP TLGLLEDPAE
560 570 580 590 600
RPVNSWASDF NTLVPVYGKA HWATISKCQG AERCDPELPK TSSFAASGPL
610 620 630 640 650
IPEENKERVQ ELPDSGALML VPNRQLTADY FEKTWLSLKV AHQQVLPWRG
660 670 680 690 700
EFHPDTLQMA LQVVNIQTIA MSRAGSRPWK AYLSAQDDTG CLFLTELLLE
710 720 730
PGNSEMQISV KQNEARTETL NSFISVLETV IGTIEEIKS
Length:739
Mass (Da):83,260
Last modified:February 20, 2007 - v2
Checksum:iB6FC92215BDA5EDC
GO
Isoform 2 (identifier: Q9Y6B7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     113-205: Missing.
     373-395: GIARTYTDQCVQILTELLGLRQE → RCLLLFLLENLDQPARKLWLEEP
     396-739: Missing.

Note: No experimental confirmation available.

Show »
Length:302
Mass (Da):34,403
Checksum:i4B5F9E603C76C5B5
GO

Sequence cautioni

The sequence BAD93054.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti140 – 1401A → V in AAD20448. (PubMed:10066790)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti480 – 4801L → S.2 Publications
Corresponds to variant rs1217401 [ dbSNP | Ensembl ].
VAR_030804

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei113 – 20593Missing in isoform 2. 1 PublicationVSP_055787Add
BLAST
Alternative sequencei373 – 39523GIART…GLRQE → RCLLLFLLENLDQPARKLWL EEP in isoform 2. 1 PublicationVSP_055788Add
BLAST
Alternative sequencei396 – 739344Missing in isoform 2. 1 PublicationVSP_055789Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF092094 mRNA. Translation: AAD20448.1.
AK298037 mRNA. Translation: BAH12709.1.
AB209817 mRNA. Translation: BAD93054.1. Different initiation.
AL137856 Genomic DNA. Translation: CAI19072.1.
BC014146 mRNA. Translation: AAH14146.1.
CCDSiCCDS865.1. [Q9Y6B7-1]
RefSeqiNP_001240781.1. NM_001253852.1. [Q9Y6B7-1]
NP_001240782.1. NM_001253853.1.
NP_006585.2. NM_006594.3. [Q9Y6B7-1]
UniGeneiHs.515048.

Genome annotation databases

EnsembliENST00000256658; ENSP00000256658; ENSG00000134262. [Q9Y6B7-1]
ENST00000369569; ENSP00000358582; ENSG00000134262. [Q9Y6B7-1]
GeneIDi10717.
KEGGihsa:10717.
UCSCiuc001eeb.3. human. [Q9Y6B7-1]

Polymorphism databases

DMDMi126302520.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF092094 mRNA. Translation: AAD20448.1 .
AK298037 mRNA. Translation: BAH12709.1 .
AB209817 mRNA. Translation: BAD93054.1 . Different initiation.
AL137856 Genomic DNA. Translation: CAI19072.1 .
BC014146 mRNA. Translation: AAH14146.1 .
CCDSi CCDS865.1. [Q9Y6B7-1 ]
RefSeqi NP_001240781.1. NM_001253852.1. [Q9Y6B7-1 ]
NP_001240782.1. NM_001253853.1.
NP_006585.2. NM_006594.3. [Q9Y6B7-1 ]
UniGenei Hs.515048.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2MJ7 NMR - A 610-739 [» ]
ProteinModelPortali Q9Y6B7.
SMRi Q9Y6B7. Positions 9-576, 609-739.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 115943. 5 interactions.
DIPi DIP-24209N.
IntActi Q9Y6B7. 1 interaction.
STRINGi 9606.ENSP00000256658.

PTM databases

PhosphoSitei Q9Y6B7.

Polymorphism databases

DMDMi 126302520.

Proteomic databases

MaxQBi Q9Y6B7.
PaxDbi Q9Y6B7.
PRIDEi Q9Y6B7.

Protocols and materials databases

DNASUi 10717.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000256658 ; ENSP00000256658 ; ENSG00000134262 . [Q9Y6B7-1 ]
ENST00000369569 ; ENSP00000358582 ; ENSG00000134262 . [Q9Y6B7-1 ]
GeneIDi 10717.
KEGGi hsa:10717.
UCSCi uc001eeb.3. human. [Q9Y6B7-1 ]

Organism-specific databases

CTDi 10717.
GeneCardsi GC01M114437.
HGNCi HGNC:572. AP4B1.
HPAi HPA028162.
HPA028399.
HPA028652.
MIMi 607245. gene.
614066. phenotype.
neXtProti NX_Q9Y6B7.
Orphaneti 280763. Severe intellectual disability and progressive spastic paraplegia.
PharmGKBi PA24864.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5096.
GeneTreei ENSGT00530000063138.
HOGENOMi HOG000294128.
HOVERGENi HBG050521.
InParanoidi Q9Y6B7.
KOi K12401.
OMAi RPWKAYL.
PhylomeDBi Q9Y6B7.
TreeFami TF354235.

Enzyme and pathway databases

Reactomei REACT_19400. Golgi Associated Vesicle Biogenesis.

Miscellaneous databases

GeneWikii AP4B1.
GenomeRNAii 10717.
NextBioi 35479587.
PROi Q9Y6B7.
SOURCEi Search...

Gene expression databases

Bgeei Q9Y6B7.
CleanExi HS_AP4B1.
ExpressionAtlasi Q9Y6B7. baseline and differential.
Genevestigatori Q9Y6B7.

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
3.30.310.10. 1 hit.
InterProi IPR026739. AP_beta.
IPR016342. AP_complex_bsu_1_2_4.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR015151. B-adaptin_app_sub_C.
IPR012295. Beta2_adaptin/TBP_C_dom.
IPR002553. Clathrin/coatomer_adapt-like_N.
[Graphical view ]
PANTHERi PTHR11134. PTHR11134. 1 hit.
Pfami PF01602. Adaptin_N. 1 hit.
PF09066. B2-adapt-app_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF002291. AP_complex_beta. 1 hit.
SMARTi SM01020. B2-adapt-app_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "AP-4, a novel protein complex related to clathrin adaptors."
    Dell'Angelica E.C., Mullins C., Bonifacino J.S.
    J. Biol. Chem. 274:7278-7285(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT SER-480.
    Tissue: Skeletal muscle.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Lung.
  3. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-480.
    Tissue: Brain.
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Skin.
  6. "Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature."
    Abou Jamra R., Philippe O., Raas-Rothschild A., Eck S.H., Graf E., Buchert R., Borck G., Ekici A., Brockschmidt F.F., Nothen M.M., Munnich A., Strom T.M., Reis A., Colleaux L.
    Am. J. Hum. Genet. 88:788-795(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: INVOLVEMENT IN CPSQ5.
  7. "Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles."
    Borner G.H., Antrobus R., Hirst J., Bhumbra G.S., Kozik P., Jackson L.P., Sahlender D.A., Robinson M.S.
    J. Cell Biol. 197:141-160(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ENTHD2, SUBCELLULAR LOCATION.
  8. "Solution NMR structure of beta-adaptin appendage domain of human adapter protein complex 4 subunit beta, Northeast structural genomics consortium (NESG) target HR8998C."
    Northeast structural genomics consortium (NESG)
    Submitted (JAN-2014) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 610-739.

Entry informationi

Entry nameiAP4B1_HUMAN
AccessioniPrimary (citable) accession number: Q9Y6B7
Secondary accession number(s): B7Z4X3, Q59EJ4, Q96CL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: February 20, 2007
Last modified: November 26, 2014
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3