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Q9Y694

- S22A7_HUMAN

UniProt

Q9Y694 - S22A7_HUMAN

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Protein

Solute carrier family 22 member 7

Gene
SLC22A7, NLT, OAT2
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.5 Publications

Kineticsi

  1. KM=713 nM for prostaglandin E22 Publications
  2. KM=440 µM for tetracycline

GO - Molecular functioni

  1. sodium-independent organic anion transmembrane transporter activity Source: ProtInc

GO - Biological processi

  1. organic anion transport Source: ProtInc
  2. response to stilbenoid Source: Ensembl
  3. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiREACT_22310. Organic anion transport.

Protein family/group databases

TCDBi2.A.1.19.25. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 22 member 7
Alternative name(s):
Novel liver transporter
Organic anion transporter 2
Short name:
hOAT2
Gene namesi
Name:SLC22A7
Synonyms:NLT, OAT2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:10971. SLC22A7.

Subcellular locationi

Basolateral cell membrane; Multi-pass membrane protein
Note: Apical side of the renal tubule.2 Publications

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121Helical; Reviewed predictionAdd
BLAST
Transmembranei146 – 16621Helical; Reviewed predictionAdd
BLAST
Transmembranei180 – 20021Helical; Reviewed predictionAdd
BLAST
Transmembranei204 – 22421Helical; Reviewed predictionAdd
BLAST
Transmembranei234 – 25421Helical; Reviewed predictionAdd
BLAST
Transmembranei259 – 27921Helical; Reviewed predictionAdd
BLAST
Transmembranei346 – 36621Helical; Reviewed predictionAdd
BLAST
Transmembranei376 – 39722Helical; Reviewed predictionAdd
BLAST
Transmembranei404 – 42320Helical; Reviewed predictionAdd
BLAST
Transmembranei432 – 45221Helical; Reviewed predictionAdd
BLAST
Transmembranei466 – 48621Helical; Reviewed predictionAdd
BLAST
Transmembranei493 – 51321Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. basolateral plasma membrane Source: UniProtKB-SubCell
  2. integral component of plasma membrane Source: ProtInc
  3. membrane Source: ProtInc
  4. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35848.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Solute carrier family 22 member 7PRO_0000317481Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi91 – 911N-linked (GlcNAc...)1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9Y694.
PRIDEiQ9Y694.

PTM databases

PhosphoSiteiQ9Y694.

Expressioni

Tissue specificityi

Expressed in liver and kidney.3 Publications

Gene expression databases

ArrayExpressiQ9Y694.
BgeeiQ9Y694.
CleanExiHS_SLC22A7.
GenevestigatoriQ9Y694.

Organism-specific databases

HPAiHPA030220.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000361666.

Structurei

3D structure databases

ProteinModelPortaliQ9Y694.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
HOGENOMiHOG000234569.
HOVERGENiHBG108433.
KOiK08204.
OMAiPMKQVQN.
OrthoDBiEOG7C8GH9.
PhylomeDBiQ9Y694.
TreeFamiTF315847.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR004749. Orgcat_transp.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00898. 2A0119. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9Y694-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MGFEELLEQV GGFGPFQLRN VALLALPRVL LPLHFLLPIF LAAVPAHRCA    50
LPGAPANFSH QDVWLEAHLP REPDGTLSSC LRFAYPQALP NTTLGEERQS 100
RGELEDEPAT VPCSQGWEYD HSEFSSTIAT ESQWDLVCEQ KGLNRAASTF 150
FFAGVLVGAV AFGYLSDRFG RRRLLLVAYV STLVLGLASA ASVSYVMFAI 200
TRTLTGSALA GFTIIVMPLE LEWLDVEHRT VAGVLSSTFW TGGVMLLALV 250
GYLIRDWRWL LLAVTLPCAP GILSLWWVPE SARWLLTQGH VKEAHRYLLH 300
CARLNGRPVC EDSFSQEAVS KVAAGERVVR RPSYLDLFRT PRLRHISLCC 350
VVVWFGVNFS YYGLSLDVSG LGLNVYQTQL LFGAVELPSK LLVYLSVRYA 400
GRRLTQAGTL LGTALAFGTR LLVSSDMKSW STVLAVMGKA FSEAAFTTAY 450
LFTSELYPTV LRQTGMGLTA LVGRLGGSLA PLAALLDGVW LSLPKLTYGG 500
IALLAAGTAL LLPETRQAQL PETIQDVERK SAPTSLQEEE MPMKQVQN 548
Length:548
Mass (Da):60,026
Last modified:November 1, 1999 - v1
Checksum:i5BA4C3FCC3C57533
GO
Isoform 2 (identifier: Q9Y694-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     132-133: Missing.

Show »
Length:546
Mass (Da):59,810
Checksum:i6A87AA1BD6FEA15C
GO
Isoform 3 (identifier: Q9Y694-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     132-133: Missing.
     531-548: SAPTSLQEEEMPMKQVQN → RCVHRTVSVYV

Show »
Length:539
Mass (Da):59,082
Checksum:iF3D6F799778EFE63
GO
Isoform 4 (identifier: Q9Y694-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-307: Missing.
     308-317: PVCEDSFSQE → MLQPHLLPYQ

Show »
Length:241
Mass (Da):26,213
Checksum:i8AF6769F5CAC8439
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti303 – 3031R → K.1 Publication
Corresponds to variant rs70953684 [ dbSNP | Ensembl ].
VAR_047875
Natural varianti327 – 3271R → W.1 Publication
Corresponds to variant rs36040909 [ dbSNP | Ensembl ].
VAR_047876
Natural varianti507 – 5071G → V.1 Publication
Corresponds to variant rs70953693 [ dbSNP | Ensembl ].
VAR_047877

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 307307Missing in isoform 4. VSP_030991Add
BLAST
Alternative sequencei132 – 1332Missing in isoform 2 and isoform 3. VSP_030992
Alternative sequencei308 – 31710PVCEDSFSQE → MLQPHLLPYQ in isoform 4. VSP_030993
Alternative sequencei531 – 54818SAPTS…KQVQN → RCVHRTVSVYV in isoform 3. VSP_030994Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti304 – 3041L → P in AAG43523. 1 Publication
Sequence conflicti413 – 4131T → A in AAG43523. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF097518 mRNA. Translation: AAD37091.1.
AF210455 mRNA. Translation: AAG43523.1.
AY050498 mRNA. Translation: AAL12496.1.
AK290796 mRNA. Translation: BAF83485.1.
AK290806 mRNA. Translation: BAF83495.1.
EU562669 Genomic DNA. Translation: ACB21045.1.
AL583834 Genomic DNA. Translation: CAI14466.1.
AL583834 Genomic DNA. Translation: CAI14462.1.
AL583834 Genomic DNA. Translation: CAI14463.1.
AL583834 Genomic DNA. Translation: CAI14464.1.
CH471081 Genomic DNA. Translation: EAX04172.1.
CH471081 Genomic DNA. Translation: EAX04175.1.
BC033805 mRNA. Translation: AAH33805.1.
CCDSiCCDS4892.1. [Q9Y694-2]
CCDS4893.2. [Q9Y694-1]
RefSeqiNP_006663.2. NM_006672.3. [Q9Y694-2]
NP_696961.2. NM_153320.2. [Q9Y694-1]
UniGeneiHs.485438.

Genome annotation databases

EnsembliENST00000372574; ENSP00000361655; ENSG00000137204. [Q9Y694-3]
ENST00000372585; ENSP00000361666; ENSG00000137204. [Q9Y694-1]
ENST00000372589; ENSP00000361670; ENSG00000137204. [Q9Y694-2]
GeneIDi10864.
KEGGihsa:10864.
UCSCiuc003ous.3. human. [Q9Y694-3]
uc003out.3. human. [Q9Y694-1]

Polymorphism databases

DMDMi74753520.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF097518 mRNA. Translation: AAD37091.1 .
AF210455 mRNA. Translation: AAG43523.1 .
AY050498 mRNA. Translation: AAL12496.1 .
AK290796 mRNA. Translation: BAF83485.1 .
AK290806 mRNA. Translation: BAF83495.1 .
EU562669 Genomic DNA. Translation: ACB21045.1 .
AL583834 Genomic DNA. Translation: CAI14466.1 .
AL583834 Genomic DNA. Translation: CAI14462.1 .
AL583834 Genomic DNA. Translation: CAI14463.1 .
AL583834 Genomic DNA. Translation: CAI14464.1 .
CH471081 Genomic DNA. Translation: EAX04172.1 .
CH471081 Genomic DNA. Translation: EAX04175.1 .
BC033805 mRNA. Translation: AAH33805.1 .
CCDSi CCDS4892.1. [Q9Y694-2 ]
CCDS4893.2. [Q9Y694-1 ]
RefSeqi NP_006663.2. NM_006672.3. [Q9Y694-2 ]
NP_696961.2. NM_153320.2. [Q9Y694-1 ]
UniGenei Hs.485438.

3D structure databases

ProteinModelPortali Q9Y694.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000361666.

Chemistry

ChEMBLi CHEMBL1955711.

Protein family/group databases

TCDBi 2.A.1.19.25. the major facilitator superfamily (mfs).

PTM databases

PhosphoSitei Q9Y694.

Polymorphism databases

DMDMi 74753520.

Proteomic databases

PaxDbi Q9Y694.
PRIDEi Q9Y694.

Protocols and materials databases

DNASUi 10864.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000372574 ; ENSP00000361655 ; ENSG00000137204 . [Q9Y694-3 ]
ENST00000372585 ; ENSP00000361666 ; ENSG00000137204 . [Q9Y694-1 ]
ENST00000372589 ; ENSP00000361670 ; ENSG00000137204 . [Q9Y694-2 ]
GeneIDi 10864.
KEGGi hsa:10864.
UCSCi uc003ous.3. human. [Q9Y694-3 ]
uc003out.3. human. [Q9Y694-1 ]

Organism-specific databases

CTDi 10864.
GeneCardsi GC06P043263.
HGNCi HGNC:10971. SLC22A7.
HPAi HPA030220.
MIMi 604995. gene.
neXtProti NX_Q9Y694.
PharmGKBi PA35848.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0477.
HOGENOMi HOG000234569.
HOVERGENi HBG108433.
KOi K08204.
OMAi PMKQVQN.
OrthoDBi EOG7C8GH9.
PhylomeDBi Q9Y694.
TreeFami TF315847.

Enzyme and pathway databases

Reactomei REACT_22310. Organic anion transport.

Miscellaneous databases

GeneWikii SLC22A7.
GenomeRNAii 10864.
NextBioi 41247.
PROi Q9Y694.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9Y694.
Bgeei Q9Y694.
CleanExi HS_SLC22A7.
Genevestigatori Q9Y694.

Family and domain databases

InterProi IPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR004749. Orgcat_transp.
[Graphical view ]
Pfami PF07690. MFS_1. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
TIGRFAMsi TIGR00898. 2A0119. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of a human liver-specific transporter, NLT."
    Kim R.B., Leake B.L., Cvetkovic M.
    Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Liver.
  2. "Identification of a human organic anion transporter 2 homolog."
    Reid G., Bahn A., Ebbinghaus C., Wolff N.A., Burckhardt G.
    Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    Tissue: Kidney.
  3. "Cloning, characterization and localization of human organic anion transporter 2."
    Kobayashi Y., Ohshiro N., Sekine T., Endoh H., Yamamoto T.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Tissue: Kidney.
  5. NIEHS SNPs program
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS LYS-303; TRP-327 AND VAL-507.
  6. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Colon.
  9. "Isolation of a family of organic anion transporters from human liver and kidney."
    Sun W., Wu R.R., van Poelje P.D., Erion M.D.
    Biochem. Biophys. Res. Commun. 283:417-422(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY.
  10. "Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors."
    Enomoto A., Takeda M., Shimoda M., Narikawa S., Kobayashi Y., Kobayashi Y., Yamamoto T., Sekine T., Cha S.H., Niwa T., Endou H.
    J. Pharmacol. Exp. Ther. 301:797-802(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  11. "Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins."
    Kimura H., Takeda M., Narikawa S., Enomoto A., Ichida K., Endou H.
    J. Pharmacol. Exp. Ther. 301:293-298(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, BIOPHYSICOCHEMICAL PROPERTIES, SUBCELLULAR LOCATION.
  12. Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
  13. "Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7])."
    Kobayashi Y., Ohshiro N., Sakai R., Ohbayashi M., Kohyama N., Yamamoto T.
    J. Pharm. Pharmacol. 57:573-578(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY.
  14. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
    Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
    J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-91.
    Tissue: Liver.

Entry informationi

Entry nameiS22A7_HUMAN
AccessioniPrimary (citable) accession number: Q9Y694
Secondary accession number(s): B2CZX6
, Q5T046, Q5T048, Q5T050, Q9H2W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 1, 1999
Last modified: September 3, 2014
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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