Reviewed, UniProtKB/Swiss-Prot Q9Y675 (SNURF_HUMAN)

Names and origin

Protein names

Recommended name:
    SNRPN upstream reading frame protein

Gene names

Name:

SNURF

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	71 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Nucleus. Ref.1
Tissue specificity	Expressed in heart, skeletal muscle and lymphoblasts (at protein level). Expressed in brain, pancreas, heart, liver, lung, kidney and skeletal muscle. Ref.1
Miscellaneous	Encoded on a bicistronic transcript that encode for two proteins, SNRPN and SNURF. In addition to the primary 1.6-kb bicistronic SNURF-SNRPN transcript, SNURF-only transcript is also detected.
Sequence similarities	Belongs to the SNURF family.

Ontologies

Keywords
Cellular component	Nucleus
Gene Ontology (GO)
Cellular component	nucleus Ref.1 Non-traceable author statement. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 71	71	SNRPN upstream reading frame protein		PRO_0000312993

Sequences

	Sequence		Length	Mass (Da)
	Q9Y675-1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 71FC8B9F247302C9	FASTA	71	8,412
	10 20 30 40 50 60 MERARDRLHL RRTTEQHVPE VEVQVKRRRT ASLSNQECQL YPRRSQQQQV PVVDFQAELR 70 QAFLAETPRG G

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An imprinted, mammalian bicistronic transcript encodes two independent proteins." Gray T.A., Saitoh S., Nicholls R.D. Proc. Natl. Acad. Sci. U.S.A. 96:5616-5621(1999) [PubMed: 10318933] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[2]	"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed: 16572171] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF101044 mRNA. Translation: AAD31391.1. AC124312 Genomic DNA. No translation available. CH471151 Genomic DNA. Translation: EAW57625.1.
IPI	IPI00024246.
RefSeq	NP_005669.2. NP_073715.1.
UniGene	Hs.564847
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q9Y675.
Genome annotation databases
Ensembl	ENSG00000214265. Homo sapiens. [Contig view]
GeneID	8926.
KEGG	hsa:8926.
Organism-specific databases
GeneCards	GC15P022751.
HGNC	HGNC:11171. SNURF.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9Y675.
Enzyme and pathway databases
Pathway_Interaction_DB	ar_pathway. Coregulation of Androgen receptor activity.
Gene expression databases
ArrayExpress	Q9Y675.
Family and domain databases
InterPro	IPR009847. SNURF. [Graphical view]
PANTHER	PTHR14508. SNURF. 1 hit.
Pfam	PF07192. SNURF. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	33560.

Entry information

Entry name

SNURF_HUMAN

Accession

Primary (citable) accession number: Q9Y675
Secondary accession number(s): A6NCW2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	November 1, 1999
Last modified:	June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)