Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9Y5N1

- HRH3_HUMAN

UniProt

Q9Y5N1 - HRH3_HUMAN

Protein

Histamine H3 receptor

Gene

HRH3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 134 (01 Oct 2014)
      Sequence version 2 (16 Nov 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.

    GO - Molecular functioni

    1. drug binding Source: Ensembl
    2. histamine receptor activity Source: ProtInc

    GO - Biological processi

    1. brain development Source: Ensembl
    2. drinking behavior Source: Ensembl
    3. eating behavior Source: Ensembl
    4. G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: ProtInc
    5. learning Source: Ensembl
    6. memory Source: Ensembl
    7. negative regulation of adenylate cyclase activity Source: Ensembl
    8. negative regulation of blood pressure Source: Ensembl
    9. negative regulation of gamma-aminobutyric acid secretion Source: Ensembl
    10. negative regulation of glutamate secretion Source: Ensembl
    11. negative regulation of serotonin secretion Source: Ensembl
    12. neurotransmitter secretion Source: ProtInc
    13. positive regulation of cytosolic calcium ion concentration Source: Ensembl
    14. positive regulation of epithelial cell proliferation Source: Ensembl
    15. regulation of norepinephrine secretion Source: Ensembl
    16. response to organic cyclic compound Source: Ensembl

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_16903. Histamine receptors.
    REACT_19231. G alpha (i) signalling events.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histamine H3 receptor
    Short name:
    H3R
    Short name:
    HH3R
    Alternative name(s):
    G-protein coupled receptor 97
    Gene namesi
    Name:HRH3
    Synonyms:GPCR97
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 20

    Organism-specific databases

    HGNCiHGNC:5184. HRH3.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: ProtInc
    2. myelin sheath Source: Ensembl
    3. neuron projection Source: Ensembl
    4. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA29458.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 445445Histamine H3 receptorPRO_0000069690Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi11 – 111N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ9Y5N1.
    PRIDEiQ9Y5N1.

    PTM databases

    PhosphoSiteiQ9Y5N1.

    Expressioni

    Tissue specificityi

    Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.

    Gene expression databases

    BgeeiQ9Y5N1.
    CleanExiHS_HRH3.
    GenevestigatoriQ9Y5N1.

    Interactioni

    Protein-protein interaction databases

    BioGridi116416. 1 interaction.
    STRINGi9606.ENSP00000342560.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Y5N1.
    SMRiQ9Y5N1. Positions 27-249, 352-427.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3939ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini61 – 7010CytoplasmicSequence Analysis
    Topological domaini92 – 10817ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini130 – 15627CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini178 – 19619ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini218 – 359142CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini381 – 39515ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini417 – 44529CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei40 – 6021Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei71 – 9121Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei109 – 12921Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei157 – 17721Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei197 – 21721Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei360 – 38021Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei396 – 41621Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi20 – 234Poly-Ala
    Compositional biasi250 – 2567Poly-Pro
    Compositional biasi292 – 2987Poly-Gly

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG289713.
    HOGENOMiHOG000048707.
    HOVERGENiHBG102132.
    InParanoidiQ9Y5N1.
    KOiK04151.
    OMAiCWGCWQK.
    OrthoDBiEOG73804R.
    PhylomeDBiQ9Y5N1.
    TreeFamiTF351747.

    Family and domain databases

    Gene3Di1.20.1070.10. 2 hits.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR003980. Histamine_H3_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR01471. HISTAMINEH3R.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequences (7)i

    Sequence statusi: Complete.

    This entry describes 7 isoformsi produced by alternative splicing. Align

    Note: Additional isoforms seem to exist.

    Isoform 1 (identifier: Q9Y5N1-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MERAPPDGPL NASGALAGEA AAAGGARGFS AAWTAVLAAL MALLIVATVL    50
    GNALVMLAFV ADSSLRTQNN FFLLNLAISD FLVGAFCIPL YVPYVLTGRW 100
    TFGRGLCKLW LVVDYLLCTS SAFNIVLISY DRFLSVTRAV SYRAQQGDTR 150
    RAVRKMLLVW VLAFLLYGPA ILSWEYLSGG SSIPEGHCYA EFFYNWYFLI 200
    TASTLEFFTP FLSVTFFNLS IYLNIQRRTR LRLDGAREAA GPEPPPEAQP 250
    SPPPPPGCWG CWQKGHGEAM PLHRYGVGEA AVGAEAGEAT LGGGGGGGSV 300
    ASPTSSSGSS SRGTERPRSL KRGSKPSASS ASLEKRMKMV SQSFTQRFRL 350
    SRDRKVAKSL AVIVSIFGLC WAPYTLLMII RAACHGHCVP DYWYETSFWL 400
    LWANSAVNPV LYPLCHHSFR RAFTKLLCPQ KLKIQPHSSL EHCWK 445
    Length:445
    Mass (Da):48,671
    Last modified:November 16, 2001 - v2
    Checksum:i2ACF7440FBE95B6C
    GO
    Isoform 2 (identifier: Q9Y5N1-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         445-445: K → KKMKKKTCL

    Show »
    Length:453
    Mass (Da):49,633
    Checksum:i4473760FA5ED7E92
    GO
    Isoform 3 (identifier: Q9Y5N1-3) [UniParc]FASTAAdd to Basket

    Also known as: H3S

    The sequence of this isoform differs from the canonical sequence as follows:
         274-353: Missing.

    Show »
    Length:365
    Mass (Da):40,624
    Checksum:i4FDD1DE0CB809F9B
    GO
    Isoform 4 (identifier: Q9Y5N1-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         85-98: Missing.

    Show »
    Length:431
    Mass (Da):47,133
    Checksum:i33C4BCC070A1DA23
    GO
    Isoform 5 (identifier: Q9Y5N1-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         197-315: Missing.

    Show »
    Length:326
    Mass (Da):36,396
    Checksum:i2EDA2E296463E616
    GO
    Isoform 6 (identifier: Q9Y5N1-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         227-342: Missing.

    Show »
    Length:329
    Mass (Da):36,943
    Checksum:i94955EC0FA4C9590
    GO
    Isoform 7 (identifier: Q9Y5N1-7) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         234-263: Missing.

    Show »
    Length:415
    Mass (Da):45,607
    Checksum:i5A0505BAD0A13E02
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti19 – 191E → D(PubMed:10347254)Curated
    Sequence conflicti19 – 191E → D1 PublicationCurated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti280 – 2801A → V in one Shy-Drager syndrome patient; rare variant with unknown pathological significance. 1 Publication
    VAR_012235

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei85 – 9814Missing in isoform 4. CuratedVSP_001881Add
    BLAST
    Alternative sequencei197 – 315119Missing in isoform 5. CuratedVSP_001882Add
    BLAST
    Alternative sequencei227 – 342116Missing in isoform 6. CuratedVSP_001883Add
    BLAST
    Alternative sequencei234 – 26330Missing in isoform 7. CuratedVSP_001884Add
    BLAST
    Alternative sequencei274 – 35380Missing in isoform 3. 1 PublicationVSP_001885Add
    BLAST
    Alternative sequencei445 – 4451K → KKMKKKTCL in isoform 2. 1 PublicationVSP_001886

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF140538 mRNA. Translation: AAD38151.1.
    AB045369 mRNA. Translation: BAB20090.1.
    AB019000 mRNA. Translation: BAB17030.1.
    AJ296652 Genomic DNA. Translation: CAC51025.1.
    AJ278250 Genomic DNA. Translation: CAC39434.1.
    AF363791 mRNA. Translation: AAK50040.1.
    AL078633 Genomic DNA. Translation: CAC04014.1.
    BC096840 mRNA. Translation: AAH96840.1.
    CCDSiCCDS13493.1. [Q9Y5N1-1]
    RefSeqiNP_009163.2. NM_007232.2. [Q9Y5N1-1]
    XP_005260323.1. XM_005260266.1. [Q9Y5N1-2]
    UniGeneiHs.251399.

    Genome annotation databases

    EnsembliENST00000317393; ENSP00000321482; ENSG00000101180. [Q9Y5N1-2]
    ENST00000340177; ENSP00000342560; ENSG00000101180. [Q9Y5N1-1]
    GeneIDi11255.
    KEGGihsa:11255.
    UCSCiuc002ycf.2. human. [Q9Y5N1-1]
    uc002ycg.3. human. [Q9Y5N1-3]
    uc002yci.3. human. [Q9Y5N1-2]

    Polymorphism databases

    DMDMi17367264.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF140538 mRNA. Translation: AAD38151.1 .
    AB045369 mRNA. Translation: BAB20090.1 .
    AB019000 mRNA. Translation: BAB17030.1 .
    AJ296652 Genomic DNA. Translation: CAC51025.1 .
    AJ278250 Genomic DNA. Translation: CAC39434.1 .
    AF363791 mRNA. Translation: AAK50040.1 .
    AL078633 Genomic DNA. Translation: CAC04014.1 .
    BC096840 mRNA. Translation: AAH96840.1 .
    CCDSi CCDS13493.1. [Q9Y5N1-1 ]
    RefSeqi NP_009163.2. NM_007232.2. [Q9Y5N1-1 ]
    XP_005260323.1. XM_005260266.1. [Q9Y5N1-2 ]
    UniGenei Hs.251399.

    3D structure databases

    ProteinModelPortali Q9Y5N1.
    SMRi Q9Y5N1. Positions 27-249, 352-427.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116416. 1 interaction.
    STRINGi 9606.ENSP00000342560.

    Chemistry

    BindingDBi Q9Y5N1.
    ChEMBLi CHEMBL2111378.
    DrugBanki DB00667. Histamine Phosphate.
    GuidetoPHARMACOLOGYi 264.

    Protein family/group databases

    GPCRDBi Search...

    PTM databases

    PhosphoSitei Q9Y5N1.

    Polymorphism databases

    DMDMi 17367264.

    Proteomic databases

    PaxDbi Q9Y5N1.
    PRIDEi Q9Y5N1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000317393 ; ENSP00000321482 ; ENSG00000101180 . [Q9Y5N1-2 ]
    ENST00000340177 ; ENSP00000342560 ; ENSG00000101180 . [Q9Y5N1-1 ]
    GeneIDi 11255.
    KEGGi hsa:11255.
    UCSCi uc002ycf.2. human. [Q9Y5N1-1 ]
    uc002ycg.3. human. [Q9Y5N1-3 ]
    uc002yci.3. human. [Q9Y5N1-2 ]

    Organism-specific databases

    CTDi 11255.
    GeneCardsi GC20M060790.
    HGNCi HGNC:5184. HRH3.
    MIMi 604525. gene.
    neXtProti NX_Q9Y5N1.
    PharmGKBi PA29458.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG289713.
    HOGENOMi HOG000048707.
    HOVERGENi HBG102132.
    InParanoidi Q9Y5N1.
    KOi K04151.
    OMAi CWGCWQK.
    OrthoDBi EOG73804R.
    PhylomeDBi Q9Y5N1.
    TreeFami TF351747.

    Enzyme and pathway databases

    Reactomei REACT_16903. Histamine receptors.
    REACT_19231. G alpha (i) signalling events.

    Miscellaneous databases

    GeneWikii Histamine_H3_receptor.
    GenomeRNAii 11255.
    NextBioi 42830.
    PROi Q9Y5N1.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9Y5N1.
    CleanExi HS_HRH3.
    Genevestigatori Q9Y5N1.

    Family and domain databases

    Gene3Di 1.20.1070.10. 2 hits.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR003980. Histamine_H3_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR01471. HISTAMINEH3R.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and functional expression of the human histamine H3 receptor."
      Lovenberg T.W., Roland B.L., Wilson S.J., Jiang X., Pyati J., Huvar A., Jackson M.R., Erlander M.G.
      Mol. Pharmacol. 55:1101-1107(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Thalamus.
    2. "Molecular cloning and characterization of a new human histamine receptor, HH4R."
      Nakamura T., Itadani H., Hidaka Y., Ohta M., Tanaka K.
      Biochem. Biophys. Res. Commun. 279:615-620(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), CHARACTERIZATION.
    3. "Genomic organization and characterization of splice variants of the human histamine H3 receptor."
      Coge F., Guenin S.-P., Audinot V., Renouard-Try A., Beauverger P., Macia C., Ouvry C., Nagel N., Rique H., Boutin J.A., Galizzi J.-P.
      Biochem. J. 355:279-288(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1; 3; 4; 5; 6 AND 7).
      Tissue: Thalamus.
    4. "Structure of the human histamine H3 receptor gene (HRH3) and identification of naturally occurring variations."
      Wiedemann P., Boenisch H., Oerters F., Bruess M.
      J. Neural Transm. 109:443-453(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT VAL-280.
      Tissue: Blood.
    5. "Cloning and functional expression of the human histamine H3S receptor."
      Ullmer C., Zirwes E., Lubbert H.
      Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    6. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).

    Entry informationi

    Entry nameiHRH3_HUMAN
    AccessioniPrimary (citable) accession number: Q9Y5N1
    Secondary accession number(s): Q4QRI7, Q9GZX2, Q9H4K8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 16, 2001
    Last sequence update: November 16, 2001
    Last modified: October 1, 2014
    This is version 134 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    Does not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human chromosome 20
      Human chromosome 20: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3