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Protein

Protein PRRC2C

Gene

PRRC2C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • poly(A) RNA binding Source: UniProtKB
  • protein C-terminus binding Source: UniProtKB

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PRRC2C
Alternative name(s):
BAT2 domain-containing protein 1
HBV X-transactivated gene 2 protein
HBV XAg-transactivated protein 2
HLA-B-associated transcript 2-like 2
Proline-rich and coiled-coil-containing protein 2C
Gene namesi
Name:PRRC2C
Synonyms:BAT2D1, BAT2L2, KIAA1096, XTP2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:24903. PRRC2C.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

DisGeNETi23215.
OpenTargetsiENSG00000117523.
PharmGKBiPA165750415.

Polymorphism and mutation databases

BioMutaiPRRC2C.
DMDMi341942262.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003492391 – 2896Protein PRRC2CAdd BLAST2896

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei27N6-acetyllysineCombined sources1
Modified residuei187PhosphoserineCombined sources1
Modified residuei191PhosphoserineCombined sources1
Modified residuei242Asymmetric dimethylarginine; alternateBy similarity1
Modified residuei242Omega-N-methylarginine; alternateCombined sources1
Modified residuei255Asymmetric dimethylarginineCombined sources1
Modified residuei266Asymmetric dimethylarginineCombined sources1
Modified residuei279Omega-N-methylarginineCombined sources1
Modified residuei281Omega-N-methylarginineCombined sources1
Modified residuei335PhosphoserineCombined sources1
Modified residuei392N6-acetyllysineCombined sources1
Modified residuei395PhosphoserineCombined sources1
Modified residuei500PhosphoserineCombined sources1
Modified residuei779PhosphoserineCombined sources1
Modified residuei785PhosphoserineCombined sources1
Modified residuei801PhosphoserineCombined sources1
Modified residuei867PhosphoserineCombined sources1
Modified residuei878PhosphoserineCombined sources1
Modified residuei920PhosphoserineCombined sources1
Modified residuei929PhosphoserineBy similarity1
Cross-linki1133Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei1242PhosphoserineCombined sources1
Modified residuei1246PhosphoserineCombined sources1
Modified residuei1248PhosphoserineCombined sources1
Modified residuei1249PhosphoserineCombined sources1
Modified residuei1263PhosphoserineCombined sources1
Modified residuei1265PhosphothreonineCombined sources1
Modified residuei1267PhosphothreonineCombined sources1
Modified residuei1544PhosphoserineCombined sources1
Modified residuei1965PhosphothreonineCombined sources1
Modified residuei1983PhosphoserineBy similarity1
Modified residuei2013PhosphoserineCombined sources1
Modified residuei2105PhosphoserineCombined sources1
Modified residuei2143PhosphoserineCombined sources1
Modified residuei2260PhosphoserineCombined sources1
Modified residuei2673PhosphothreonineCombined sources1
Modified residuei2682PhosphothreonineCombined sources1
Modified residuei2686PhosphoserineCombined sources1
Modified residuei2694PhosphoserineCombined sources1
Modified residuei2814Omega-N-methylarginineBy similarity1
Modified residuei2823Asymmetric dimethylarginine; alternateBy similarity1
Modified residuei2823Omega-N-methylarginine; alternateBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9Y520.
PaxDbiQ9Y520.
PeptideAtlasiQ9Y520.
PRIDEiQ9Y520.

PTM databases

iPTMnetiQ9Y520.
PhosphoSitePlusiQ9Y520.

Expressioni

Tissue specificityi

Overexpressed in bladder cancer.1 Publication

Gene expression databases

BgeeiENSG00000117523.
CleanExiHS_BAT2D1.
ExpressionAtlasiQ9Y520. baseline and differential.
GenevisibleiQ9Y520. HS.

Organism-specific databases

HPAiHPA025766.
HPA028659.

Interactioni

GO - Molecular functioni

  • protein C-terminus binding Source: UniProtKB

Protein-protein interaction databases

BioGridi116822. 35 interactors.
DIPiDIP-47285N.
IntActiQ9Y520. 26 interactors.
MINTiMINT-2823741.
STRINGi9606.ENSP00000343629.

Structurei

3D structure databases

ProteinModelPortaliQ9Y520.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1020 – 1046Sequence analysisAdd BLAST27
Coiled coili1682 – 1717Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi407 – 410Poly-Pro4
Compositional biasi467 – 650Glu-richAdd BLAST184
Compositional biasi666 – 703Gln-richAdd BLAST38
Compositional biasi697 – 769Pro-richAdd BLAST73
Compositional biasi1059 – 1082Pro-richAdd BLAST24
Compositional biasi1341 – 1443Arg-richAdd BLAST103
Compositional biasi1760 – 1934Ala-richAdd BLAST175
Compositional biasi2345 – 2634Gln-richAdd BLAST290

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4817. Eukaryota.
ENOG4111VEG. LUCA.
GeneTreeiENSGT00530000063496.
HOVERGENiHBG107491.
InParanoidiQ9Y520.
TreeFamiTF328738.

Family and domain databases

InterProiIPR009738. BAT2_N.
IPR033184. PRRC2.
[Graphical view]
PANTHERiPTHR14038. PTHR14038. 4 hits.
PfamiPF07001. BAT2_N. 1 hit.
[Graphical view]

Sequences (7)i

Sequence statusi: Complete.

This entry describes 7 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9Y520-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSEKSGQSTK AKDGKKYATL SLFNTYKGKS LETQKTTARH GLQSLGKVGI
60 70 80 90 100
SRRMPPPANL PSLKAENKGN DPNVNIVPKD GTGWASKQEQ HEEEKTPEVP
110 120 130 140 150
PAQPKPGVAA PPEVAPAPKS WASNKQGGQG DGIQVNSQFQ QEFPSLQAAG
160 170 180 190 200
DQEKKEKETN DDNYGPGPSL RPPNVACWRD GGKAAGSPSS SDQDEKLPGQ
210 220 230 240 250
DESTAGTSEQ NDILKVVEKR IACGPPQAKL NGQQAALASQ YRAMMPPYMF
260 270 280 290 300
QQYPRMTYPP LHGPMRFPPS LSETNKGLRG RGPPPSWASE PERPSILSAS
310 320 330 340 350
ELKELDKFDN LDAEADEGWA GAQMEVDYTE QLNFSDDDEQ GSNSPKENNS
360 370 380 390 400
EDQGSKASEN NENKKETDEV SNTKSSSQIP AQPSVAKVPY GKGPSFNQER
410 420 430 440 450
GTSSHLPPPP KLLAQQHPPP DRQAVPGRPG PFPSKQQVAD EDEIWKQRRR
460 470 480 490 500
QQSEISAAVE RARKRREEEE RRMEEQRKAA CAEKLKRLDE KLGILEKQPS
510 520 530 540 550
PEEIRERERE KEREREKELE KEQEQEREKE REKDRERQQE KEKELEKEQE
560 570 580 590 600
KQREMEKERK QEKEKELERQ KEKEKELQKM KEQEKECELE KEREKLEEKI
610 620 630 640 650
EPREPNLEPM VEKQESENSC NKEEEPVFTR QDSNRSEKEA TPVVHETEPE
660 670 680 690 700
SGSQPRPAVL SGYFKQFQKS LPPRFQRQQE QMKQQQWQQQ QQQGVLPQTV
710 720 730 740 750
PSQPSSSTVP PPPHRPLYQP MQPHPQHLAS MGFDPRWLMM QSYMDPRMMS
760 770 780 790 800
GRPAMDIPPI HPGMIPPKPL MRRDQMEGSP NSSESFEHIA RSARDHAISL
810 820 830 840 850
SEPRMLWGSD PYPHAEPQQA TTPKATEEPE DVRSEAALDQ EQITAAYSVE
860 870 880 890 900
HNQLEAHPKA DFIRESSEAQ VQKFLSRSVE DVRPHHTDAN NQSACFEAPD
910 920 930 940 950
QKTLSAPQEE RISAVESQPS RKRSVSHGSN HTQKPDEQRS EPSAGIPKVT
960 970 980 990 1000
SRCIDSKEPI ERPEEKPKKE GFIRSSEGPK PEKVYKSKSE TRWGPRPSSN
1010 1020 1030 1040 1050
RREEVNDRPV RRSGPIKKPV LRDMKEEREQ RKEKEGEKAE KVTEKVVVKP
1060 1070 1080 1090 1100
EKTEKKDLPP PPPPPQPPAP IQPQSVPPPI QPEAEKFPST ETATLAQKPS
1110 1120 1130 1140 1150
QDTEKPLEPV STVQVEPAVK TVNQQTMAAP VVKEEKQPEK VISKDLVIER
1160 1170 1180 1190 1200
PRPDSRPAVK KESTLPPRTY WKEARERDWF PDQGYRGRGR GEYYSRGRSY
1210 1220 1230 1240 1250
RGSYGGRGRG GRGHTRDYPQ YRDNKPRAEH IPSGPLRQRE ESETRSESSD
1260 1270 1280 1290 1300
FEVVPKRRRQ RGSETDTDSE IHESASDKDS LSKGKLPKRE ERPENKKPVK
1310 1320 1330 1340 1350
PHSSFKPDNH VRIDNRLLEK PYVRDDDKAK PGFLPKGEPT RRGRGGTFRR
1360 1370 1380 1390 1400
GGRDPGGRPS RPSTLRRPAY RDNQWNPRQS EVPKPEDGEP PRRHEQFIPI
1410 1420 1430 1440 1450
AADKRPPKFE RKFDPARERP RRQRPTRPPR QDKPPRFRRL REREAASKSN
1460 1470 1480 1490 1500
EVVAVPTNGT VNNVAQEPVN TLGDISGNKT PDLSNQNSSD QANEEWETAS
1510 1520 1530 1540 1550
ESSDFNERRE RDEKKNADLN AQTVVKVGEN VLPPKREIAK RSFSSQRPVD
1560 1570 1580 1590 1600
RQNRRGNNGP PKSGRNFSGP RNERRSGPPS KSGKRGPFDD QPAGTTGVDL
1610 1620 1630 1640 1650
INGSSAHHQE GVPNGTGQKN SKDSTGKKRE DPKPGPKKPK EKVDALSQFD
1660 1670 1680 1690 1700
LNNYASVVII DDHPEVTVIE DPQSNLNDDG FTEVVSKKQQ KRLQDEERRK
1710 1720 1730 1740 1750
KEEQVIQVWN KKNANEKGRS QTSKLPPRFA KKQATGIQQA QSSASVPPLA
1760 1770 1780 1790 1800
SAPLPPSTSA SVPASTSAPL PATLTPVPAS TSAPVPASTL APVLASTSAP
1810 1820 1830 1840 1850
VPASPLAPVS ASASVSASVP ASTSAAAITS SSAPASAPAP TPILASVSTP
1860 1870 1880 1890 1900
ASVTILASAS IPILASALAS TSAPTPAPAA SSPAAPVITA PTIPASAPTA
1910 1920 1930 1940 1950
SVPLAPASAS APAPAPTPVS APNPAPPAPA QTQAQTHKPV QNPLQTTSQS
1960 1970 1980 1990 2000
SKQPPPSIRL PSAQTPNGTD YVASGKSIQT PQSHGTLTAE LWDNKVAPPA
2010 2020 2030 2040 2050
VLNDISKKLG PISPPQPPSV SAWNKPLTSF GSAPSSEGAK NGQESGLEIG
2060 2070 2080 2090 2100
TDTIQFGAPA SNGNENEVVP VLSEKSADKI PEPKEQRQKQ PRAGPIKAQK
2110 2120 2130 2140 2150
LPDLSPVENK EHKPGPIGKE RSLKNRKVKD AQQVEPEGQE KPSPATVRST
2160 2170 2180 2190 2200
DPVTTKETKA VSEMSTEIGT MISVSSAEYG TNAKESVTDY TTPSSSLPNT
2210 2220 2230 2240 2250
VATNNTKMED TLVNNVPLPN TLPLPKRETI QQSSSLTSVP PTTFSLTFKM
2260 2270 2280 2290 2300
ESARKAWENS PNVREKGSPV TSTAPPIATG VSSSASGPST ANYNSFSSAS
2310 2320 2330 2340 2350
MPQIPVASVT PTASLSGAGT YTTSSLSTKS TTTSDPPNIC KVKPQQLQTS
2360 2370 2380 2390 2400
SLPSASHFSQ LSCMPSLIAQ QQQNPQVYVS QSAAAQIPAF YMDTSHLFNT
2410 2420 2430 2440 2450
QHARLAPPSL AQQQGFQPGL SQPTSVQQIP IPIYAPLQGQ HQAQLSLGAG
2460 2470 2480 2490 2500
PAVSQAQELF SSSLQPYRSQ PAFMQSSLSQ PSVVLSGTAI HNFPTVQHQE
2510 2520 2530 2540 2550
LAKAQSGLAF QQTSNTQPIP ILYEHQLGQA SGLGGSQLID THLLQARANL
2560 2570 2580 2590 2600
TQASNLYSGQ VQQPGQTNFY NTAQSPSALQ QVTVPLPASQ LSLPNFGSTG
2610 2620 2630 2640 2650
QPLIALPQTL QPPLQHTTPQ AQAQSLSRPA QVSQPFRGLI PAGTQHSMIA
2660 2670 2680 2690 2700
TTGKMSEMEL KAFGSGIDIK PGTPPIAGRS TTPTSSPFRA TSTSPNSQSS
2710 2720 2730 2740 2750
KMNSIVYQKQ FQSAPATVRM TQPFPTQFAP QILSQPNLVP PLVRAPHTNT
2760 2770 2780 2790 2800
FPAPVQRPPM ALASQMPPPL TTGLMSHARL PHVARGPCGS LSGVRGNQAQ
2810 2820 2830 2840 2850
AALKAEQDMK AKQRAEVLQS TQRFFSEQQQ SKQIGGGKAQ KVDSDSSKPP
2860 2870 2880 2890
ETLTDPPGVC QEKVEEKPPP APSIATKPVR TGPIKPQAIK TEETKS
Length:2,896
Mass (Da):316,911
Last modified:July 27, 2011 - v4
Checksum:iF0E037C36F04CDF9
GO
Isoform 2 (identifier: Q9Y520-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-243: Missing.

Note: No experimental confirmation available.
Show »
Length:2,653
Mass (Da):291,093
Checksum:i5B06B2406E7FC347
GO
Isoform 3 (identifier: Q9Y520-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2687-2700: PFRATSTSPNSQSS → SGLLLQVRTASPAK
     2701-2896: Missing.

Show »
Length:2,700
Mass (Da):295,733
Checksum:iFBEC4B4580ECA402
GO
Isoform 4 (identifier: Q9Y520-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2732-2810: Missing.

Note: No experimental confirmation available.
Show »
Length:2,817
Mass (Da):308,606
Checksum:i1144BD9471FD2570
GO
Isoform 5 (identifier: Q9Y520-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1759-1805: Missing.

Note: No experimental confirmation available.
Show »
Length:2,849
Mass (Da):312,635
Checksum:i4E4843B14F53235D
GO
Isoform 6 (identifier: Q9Y520-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2185-2249: Missing.
     2732-2810: Missing.

Note: No experimental confirmation available.
Show »
Length:2,752
Mass (Da):301,572
Checksum:i523B278DD55A9333
GO
Isoform 7 (identifier: Q9Y520-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     37-37: T → TVA

Note: No experimental confirmation available.
Show »
Length:2,898
Mass (Da):317,081
Checksum:iC2552AD6C203426C
GO

Sequence cautioni

The sequence AAH06090 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH45713 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH58930 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAA90997 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti454 – 456EIS → GIY in AAH45713 (PubMed:15489334).Curated3
Sequence conflicti561Q → P in AAH45713 (PubMed:15489334).Curated1
Sequence conflicti1940V → A in CAB82345 (PubMed:17974005).Curated1
Sequence conflicti2443A → V in BAB14056 (PubMed:14702039).Curated1
Sequence conflicti2539I → V in BAA90997 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_046290235A → T.Corresponds to variant rs10913157dbSNPEnsembl.1
Natural variantiVAR_046291343N → K.Corresponds to variant rs36013361dbSNPEnsembl.1
Natural variantiVAR_046292468E → G.Corresponds to variant rs704839dbSNPEnsembl.1
Natural variantiVAR_046293906A → T.Combined sourcesCorresponds to variant rs760644dbSNPEnsembl.1
Natural variantiVAR_046294959P → S.Corresponds to variant rs34269512dbSNPEnsembl.1
Natural variantiVAR_0462951624S → C.1 PublicationCorresponds to variant rs235468dbSNPEnsembl.1
Natural variantiVAR_0462961771P → S.Corresponds to variant rs1687056dbSNPEnsembl.1
Natural variantiVAR_0462971868L → R.Corresponds to variant rs3820169dbSNPEnsembl.1
Natural variantiVAR_0462981885A → T.Corresponds to variant rs12025905dbSNPEnsembl.1
Natural variantiVAR_0462991924P → R.Corresponds to variant rs183523dbSNPEnsembl.1
Natural variantiVAR_0595842717T → A.Corresponds to variant rs2421847dbSNPEnsembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0352441 – 243Missing in isoform 2. 1 PublicationAdd BLAST243
Alternative sequenceiVSP_03525037T → TVA in isoform 7. 2 Publications1
Alternative sequenceiVSP_0352451759 – 1805Missing in isoform 5. 1 PublicationAdd BLAST47
Alternative sequenceiVSP_0352462185 – 2249Missing in isoform 6. 1 PublicationAdd BLAST65
Alternative sequenceiVSP_0352472687 – 2700PFRAT…NSQSS → SGLLLQVRTASPAK in isoform 3. 2 PublicationsAdd BLAST14
Alternative sequenceiVSP_0352482701 – 2896Missing in isoform 3. 2 PublicationsAdd BLAST196
Alternative sequenceiVSP_0352492732 – 2810Missing in isoform 4 and isoform 6. 2 PublicationsAdd BLAST79

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF488829 mRNA. Translation: AAO49478.1.
AL096857 mRNA. Translation: CAB51071.1.
AL021579 Genomic DNA. No translation available.
Z98750 Genomic DNA. No translation available.
AF253978 mRNA. Translation: AAG44627.1.
BC006090 mRNA. Translation: AAH06090.1. Sequence problems.
BC045713 mRNA. Translation: AAH45713.1. Sequence problems.
BC058930 mRNA. Translation: AAH58930.1. Sequence problems.
AB029019 mRNA. Translation: BAA83048.2.
AL133635 mRNA. Translation: CAB63759.1.
AL162004 mRNA. Translation: CAB82345.1.
AK000190 mRNA. Translation: BAA90997.1. Sequence problems.
AK022492 mRNA. Translation: BAB14056.1.
CCDSiCCDS1296.2. [Q9Y520-4]
PIRiT43454.
T47182.
RefSeqiNP_055987.2. NM_015172.3. [Q9Y520-4]
XP_005245074.1. XM_005245017.2. [Q9Y520-7]
XP_006711301.1. XM_006711238.3. [Q9Y520-1]
UniGeneiHs.494614.

Genome annotation databases

EnsembliENST00000338920; ENSP00000343629; ENSG00000117523. [Q9Y520-4]
ENST00000426496; ENSP00000410219; ENSG00000117523. [Q9Y520-4]
GeneIDi23215.
KEGGihsa:23215.
UCSCiuc010pmg.3. human. [Q9Y520-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF488829 mRNA. Translation: AAO49478.1.
AL096857 mRNA. Translation: CAB51071.1.
AL021579 Genomic DNA. No translation available.
Z98750 Genomic DNA. No translation available.
AF253978 mRNA. Translation: AAG44627.1.
BC006090 mRNA. Translation: AAH06090.1. Sequence problems.
BC045713 mRNA. Translation: AAH45713.1. Sequence problems.
BC058930 mRNA. Translation: AAH58930.1. Sequence problems.
AB029019 mRNA. Translation: BAA83048.2.
AL133635 mRNA. Translation: CAB63759.1.
AL162004 mRNA. Translation: CAB82345.1.
AK000190 mRNA. Translation: BAA90997.1. Sequence problems.
AK022492 mRNA. Translation: BAB14056.1.
CCDSiCCDS1296.2. [Q9Y520-4]
PIRiT43454.
T47182.
RefSeqiNP_055987.2. NM_015172.3. [Q9Y520-4]
XP_005245074.1. XM_005245017.2. [Q9Y520-7]
XP_006711301.1. XM_006711238.3. [Q9Y520-1]
UniGeneiHs.494614.

3D structure databases

ProteinModelPortaliQ9Y520.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116822. 35 interactors.
DIPiDIP-47285N.
IntActiQ9Y520. 26 interactors.
MINTiMINT-2823741.
STRINGi9606.ENSP00000343629.

PTM databases

iPTMnetiQ9Y520.
PhosphoSitePlusiQ9Y520.

Polymorphism and mutation databases

BioMutaiPRRC2C.
DMDMi341942262.

Proteomic databases

EPDiQ9Y520.
PaxDbiQ9Y520.
PeptideAtlasiQ9Y520.
PRIDEiQ9Y520.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000338920; ENSP00000343629; ENSG00000117523. [Q9Y520-4]
ENST00000426496; ENSP00000410219; ENSG00000117523. [Q9Y520-4]
GeneIDi23215.
KEGGihsa:23215.
UCSCiuc010pmg.3. human. [Q9Y520-1]

Organism-specific databases

CTDi23215.
DisGeNETi23215.
GeneCardsiPRRC2C.
H-InvDBHIX0001329.
HIX0159969.
HGNCiHGNC:24903. PRRC2C.
HPAiHPA025766.
HPA028659.
neXtProtiNX_Q9Y520.
OpenTargetsiENSG00000117523.
PharmGKBiPA165750415.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4817. Eukaryota.
ENOG4111VEG. LUCA.
GeneTreeiENSGT00530000063496.
HOVERGENiHBG107491.
InParanoidiQ9Y520.
TreeFamiTF328738.

Miscellaneous databases

ChiTaRSiPRRC2C. human.
GenomeRNAii23215.
PROiQ9Y520.

Gene expression databases

BgeeiENSG00000117523.
CleanExiHS_BAT2D1.
ExpressionAtlasiQ9Y520. baseline and differential.
GenevisibleiQ9Y520. HS.

Family and domain databases

InterProiIPR009738. BAT2_N.
IPR033184. PRRC2.
[Graphical view]
PANTHERiPTHR14038. PTHR14038. 4 hits.
PfamiPF07001. BAT2_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPRC2C_HUMAN
AccessioniPrimary (citable) accession number: Q9Y520
Secondary accession number(s): Q05DM8
, Q49A39, Q6PD54, Q9H2N2, Q9HA05, Q9NSM8, Q9NXL3, Q9UF29, Q9UPQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 27, 2011
Last modified: November 2, 2016
This is version 106 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.