Q9Y4X1 (UD2A1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-glucuronosyltransferase 2A1
Short name=UDPGT 2A1
EC=2.4.1.17

Gene names

Name:	UGT2A1
Synonyms:	UGT2A2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	527 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium. Ref.2
Catalytic activity	UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
Subcellular location	Membrane; Single-pass type I membrane protein Potential.
Tissue specificity	Olfactory epithelium and brain. Isoform 2 is mainly expressed in the nasal mucosa. Ref.1 Ref.2
Sequence similarities	Belongs to the UDP-glycosyltransferase family.
Caution	According to HGNC, UGT2A1 and UGT2A2 are 2 separate genes. However, they share common exons at the C-terminus, suggesting that UGT2A1 and UGT2A2 are different isoforms encoded by the same locus.
Biophysicochemical properties	Kinetic parameters: KM=75.4 µM for 3-hydroxybiphenyl Ref.1 KM=59.5 µM for umbelliferone KM=51.6 µM for S---b-citronellol KM=170.1 µM for borneol KM=56.2 µM for testosterone KM=251 µM for UDP-glucuronate Vmax=2.60 nmol/min/mg enzyme with 3-hydroxybiphenyl as substrate Vmax=0.61 nmol/min/mg enzyme with umbelliferone as substrate Vmax=1.98 nmol/min/mg enzyme with S---b-citronellol as substrate Vmax=1.05 nmol/min/mg enzyme with borneol as substrate Vmax=0.25 nmol/min/mg enzyme with testosterone as substrate

Ontologies

Keywords
Biological process	Olfaction Sensory transduction
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Signal Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular glucuronidation Inferred from direct assay Ref.2. Source: BHF-UCL detection of chemical stimulus Traceable author statement Ref.1. Source: ProtInc sensory perception of smell Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	glucuronosyltransferase activity Inferred from direct assay Ref.2. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9Y4X1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9Y4X1-2)

Also known as: UGT2A2;

The sequence of this isoform differs from the canonical sequence as follows:
     1-237: MLNNLLLFSL...KSWDSYYSKA → MVSIRDFTMP...GEWNSYYSKI

Isoform 3 (identifier: Q9Y4X1-3)

Also known as: UGT2A2 variant 1;

The sequence of this isoform differs from the canonical sequence as follows:
     1-237: MLNNLLLFSL...KSWDSYYSKA → MVSIRDFTMP...GEWNSYYSKI
     288-331: Missing.

Isoform 4 (identifier: Q9Y4X1-4)

The sequence of this isoform differs from the canonical sequence as follows:
     237-237: A → ALDGSHWLNI...GEWNSYYSKI
     288-331: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q9Y4X1-5)

The sequence of this isoform differs from the canonical sequence as follows:
     238-238: L → LGGLLLCCPGWSAVADLGSLQPLLPGFKRFSRLSLHCSWDYRLPA
     288-331: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 527	507	UDP-glucuronosyltransferase 2A1		PRO_0000036023
Regions
	Topological domain	21 – 490	470	Extracellular Potential
	Transmembrane	491 – 507	17	Helical; Potential
	Topological domain	508 – 527	20	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	49	1	N-linked (GlcNAc...) Potential
	Glycosylation	313	1	N-linked (GlcNAc...) Potential
	Glycosylation	347	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 237	237	MLNNL…YYSKA → MVSIRDFTMPKKFVQMLVFN LTLTEVVLSGNVLIWPTDGS HWLNIKIILEELIQRNHNVT VLASSATLFINSNPDSPVNF EVIPVSYKKSNIDSLIEHMI MLWIDHRPTPLTIWAFYKEL GKLLDTFFQINIQLCDGVLK NPKLMARLQKGGFDVLVADP VTICGDLVALKLGIPFMYTL RFSPASTVERHCGKIPAPVS YVPAALSELTDQMTFGERIK NTISYSLQDYIFQSYWGEWN SYYSKI in isoform 2 and isoform 3.		VSP_039375
	Alternative sequence	237	1	A → ALDGSHWLNIKIILEELIQR NHNVTVLASSATLFINSNPD SPVNFEVIPVSYKKSNIDSL IEHMIMLWIDHRPTPLTIWA FYKELGKLLDTFFQINIQLC DGVLKNPKLMARLQKGGFDV LVADPVTICGDLVALKLGIP FMYTLRFSPASTVERHCGKI PAPVSYVPAALSELTDQMTF GERIKNTISYSLQDYIFQSY WGEWNSYYSKI in isoform 4.		VSP_044733
	Alternative sequence	238	1	L → LGGLLLCCPGWSAVADLGSL QPLLPGFKRFSRLSLHCSWD YRLPA in isoform 5.		VSP_045577
	Alternative sequence	288 – 331	44	Missing in isoform 3, isoform 4 and isoform 5.		VSP_039376
	Natural variant	75	1	R → K. Ref.1 Ref.3 Corresponds to variant rs1347046 [ dbSNP | Ensembl ].		VAR_063113
	Natural variant	308	1	G → R. Corresponds to variant rs4148301 [ dbSNP | Ensembl ].		VAR_024686
	Natural variant	391	1	V → I. Ref.3 Corresponds to variant rs4148304 [ dbSNP | Ensembl ].		VAR_057326
Experimental info
	Sequence conflict	92	1	L → S in CAB41974. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 2. Checksum: C55858D7185273A8	FASTA	527	59,926
	10 20 30 40 50 60 MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 70 80 90 100 110 120 ITPTSNPSLT FEIYRVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 130 140 150 160 170 180 VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 190 200 210 220 230 240 KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALGR 250 260 270 280 290 300 PTTLCETMGK AEIWLIRTYW DFEFPRPYLP NFEFVGGLHC KPAKPLPKEM EEFIQSSGKN 310 320 330 340 350 360 GVVVFSLGSM VKNLTEEKAN LIASALAQIP QKVLWRYKGK KPATLGNNTQ LFDWIPQNDL 370 380 390 400 410 420 LGHPKTKAFI THGGTNGIYE AIYHGVPMVG VPMFADQPDN IAHMKAKGAA VEVNLNTMTS 430 440 450 460 470 480 VDLLSALRTV INEPSYKENA MRLSRIHHDQ PVKPLDRAVF WIEFVMRHKG AKHLRVAAHD 490 500 510 520 LTWFQYHSLD VIGFLLVCVT TAIFLVIQCC LFSCQKFGKI GKKKKRE
	Isoform 2 (UGT2A2) [UniParc]. Checksum: 2234435E46224749	FASTA	536	60,772
	10 20 30 40 50 60 MVSIRDFTMP KKFVQMLVFN LTLTEVVLSG NVLIWPTDGS HWLNIKIILE ELIQRNHNVT 70 80 90 100 110 120 VLASSATLFI NSNPDSPVNF EVIPVSYKKS NIDSLIEHMI MLWIDHRPTP LTIWAFYKEL 130 140 150 160 170 180 GKLLDTFFQI NIQLCDGVLK NPKLMARLQK GGFDVLVADP VTICGDLVAL KLGIPFMYTL 190 200 210 220 230 240 RFSPASTVER HCGKIPAPVS YVPAALSELT DQMTFGERIK NTISYSLQDY IFQSYWGEWN 250 260 270 280 290 300 SYYSKILGRP TTLCETMGKA EIWLIRTYWD FEFPRPYLPN FEFVGGLHCK PAKPLPKEME 310 320 330 340 350 360 EFIQSSGKNG VVVFSLGSMV KNLTEEKANL IASALAQIPQ KVLWRYKGKK PATLGNNTQL 370 380 390 400 410 420 FDWIPQNDLL GHPKTKAFIT HGGTNGIYEA IYHGVPMVGV PMFADQPDNI AHMKAKGAAV 430 440 450 460 470 480 EVNLNTMTSV DLLSALRTVI NEPSYKENAM RLSRIHHDQP VKPLDRAVFW IEFVMRHKGA 490 500 510 520 530 KHLRVAAHDL TWFQYHSLDV IGFLLVCVTT AIFLVIQCCL FSCQKFGKIG KKKKRE
	Isoform 3 (UGT2A2 variant 1) [UniParc]. Checksum: 4A3E94D5433A9289	FASTA	492	56,053
	10 20 30 40 50 60 MVSIRDFTMP KKFVQMLVFN LTLTEVVLSG NVLIWPTDGS HWLNIKIILE ELIQRNHNVT 70 80 90 100 110 120 VLASSATLFI NSNPDSPVNF EVIPVSYKKS NIDSLIEHMI MLWIDHRPTP LTIWAFYKEL 130 140 150 160 170 180 GKLLDTFFQI NIQLCDGVLK NPKLMARLQK GGFDVLVADP VTICGDLVAL KLGIPFMYTL 190 200 210 220 230 240 RFSPASTVER HCGKIPAPVS YVPAALSELT DQMTFGERIK NTISYSLQDY IFQSYWGEWN 250 260 270 280 290 300 SYYSKILGRP TTLCETMGKA EIWLIRTYWD FEFPRPYLPN FEFVGGLHCK PAKPLPKVLW 310 320 330 340 350 360 RYKGKKPATL GNNTQLFDWI PQNDLLGHPK TKAFITHGGT NGIYEAIYHG VPMVGVPMFA 370 380 390 400 410 420 DQPDNIAHMK AKGAAVEVNL NTMTSVDLLS ALRTVINEPS YKENAMRLSR IHHDQPVKPL 430 440 450 460 470 480 DRAVFWIEFV MRHKGAKHLR VAAHDLTWFQ YHSLDVIGFL LVCVTTAIFL VIQCCLFSCQ 490 KFGKIGKKKK RE
	Isoform 4 [UniParc]. Checksum: 7310B7229C9E2AA1	FASTA	693	79,091
	10 20 30 40 50 60 MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 70 80 90 100 110 120 ITPTSNPSLT FEIYRVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 130 140 150 160 170 180 VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 190 200 210 220 230 240 KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALDG 250 260 270 280 290 300 SHWLNIKIIL EELIQRNHNV TVLASSATLF INSNPDSPVN FEVIPVSYKK SNIDSLIEHM 310 320 330 340 350 360 IMLWIDHRPT PLTIWAFYKE LGKLLDTFFQ INIQLCDGVL KNPKLMARLQ KGGFDVLVAD 370 380 390 400 410 420 PVTICGDLVA LKLGIPFMYT LRFSPASTVE RHCGKIPAPV SYVPAALSEL TDQMTFGERI 430 440 450 460 470 480 KNTISYSLQD YIFQSYWGEW NSYYSKILGR PTTLCETMGK AEIWLIRTYW DFEFPRPYLP 490 500 510 520 530 540 NFEFVGGLHC KPAKPLPKVL WRYKGKKPAT LGNNTQLFDW IPQNDLLGHP KTKAFITHGG 550 560 570 580 590 600 TNGIYEAIYH GVPMVGVPMF ADQPDNIAHM KAKGAAVEVN LNTMTSVDLL SALRTVINEP 610 620 630 640 650 660 SYKENAMRLS RIHHDQPVKP LDRAVFWIEF VMRHKGAKHL RVAAHDLTWF QYHSLDVIGF 670 680 690 LLVCVTTAIF LVIQCCLFSC QKFGKIGKKK KRE
	Isoform 5 [UniParc]. Checksum: B5E0848AD4D14497	FASTA	527	59,991
	10 20 30 40 50 60 MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 70 80 90 100 110 120 ITPTSNPSLT FEIYRVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 130 140 150 160 170 180 VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 190 200 210 220 230 240 KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALGG 250 260 270 280 290 300 LLLCCPGWSA VADLGSLQPL LPGFKRFSRL SLHCSWDYRL PAGRPTTLCE TMGKAEIWLI 310 320 330 340 350 360 RTYWDFEFPR PYLPNFEFVG GLHCKPAKPL PKVLWRYKGK KPATLGNNTQ LFDWIPQNDL 370 380 390 400 410 420 LGHPKTKAFI THGGTNGIYE AIYHGVPMVG VPMFADQPDN IAHMKAKGAA VEVNLNTMTS 430 440 450 460 470 480 VDLLSALRTV INEPSYKENA MRLSRIHHDQ PVKPLDRAVF WIEFVMRHKG AKHLRVAAHD 490 500 510 520 LTWFQYHSLD VIGFLLVCVT TAIFLVIQCC LFSCQKFGKI GKKKKRE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase." Jedlitschky G.A., Cassidy A.J., Sales M., Pratt N., Burchell B. Biochem. J. 340:837-843(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), BIOPHYSICOCHEMICAL PROPERTIES, TISSUE SPECIFICITY, VARIANT LYS-75. Tissue: Olfactory bulb.
[2]	"Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3." Sneitz N., Court M.H., Zhang X., Laajanen K., Yee K.K., Dalton P., Ding X., Finel M. Pharmacogenet. Genomics 19:923-934(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3), FUNCTION, TISSUE SPECIFICITY. Tissue: Nasal mucosa.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 5), VARIANTS LYS-75 AND ILE-391. Tissue: Trachea.
[4]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ006054 mRNA. Translation: CAB41974.1. FJ664272 mRNA. Translation: ACV70034.1. FJ664273 mRNA. Translation: ACV70035.1. AK304249 mRNA. Translation: BAG65116.1. AK314209 mRNA. No translation available. AC093829 Genomic DNA. No translation available.
IPI	IPI00869317. IPI00908801. IPI00955955. IPI00966300.
RefSeq	NP_001099147.2. NM_001105677.2. NP_001239203.1. NM_001252274.1. NP_001239204.1. NM_001252275.1. NP_006789.2. NM_006798.3.
UniGene	Hs.225950.
3D structure databases
ProteinModelPortal	Q9Y4X1.
SMR	Q9Y4X1. Positions 222-445.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000286604.
Protein family/group databases
CAZy	GT1. Glycosyltransferase Family 1.
PTM databases
PhosphoSite	Q9Y4X1.
Polymorphism databases
DMDM	296452854.
Proteomic databases
PaxDb	Q9Y4X1.
PRIDE	Q9Y4X1.
Protocols and materials databases
DNASU	10941.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000286604; ENSP00000286604; ENSG00000173610. ENST00000457664; ENSP00000387888; ENSG00000173610. ENST00000503640; ENSP00000424478; ENSG00000173610. ENST00000514019; ENSP00000425497; ENSG00000173610.
GeneID	10941. 574537.
KEGG	hsa:10941. hsa:574537.
UCSC	uc003hem.4. human. uc010ihs.3. human. uc021xox.1. human.
Organism-specific databases
CTD	10941. 574537.
GeneCards	GC04M070454. GC04M070489.
H-InvDB	HIX0031395.
HGNC	HGNC:12542. UGT2A1. HGNC:28183. UGT2A2.
HPA	HPA017261.
MIM	604716. gene.
neXtProt	NX_Q9Y4X1.
PharmGKB	PA37184.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG1819.
HOGENOM	HOG000220831.
HOVERGEN	HBG004033.
InParanoid	Q9Y4X1.
KO	K00699.
OMA	VIKDFHV.
PhylomeDB	Q9Y4X1.
Enzyme and pathway databases
Reactome	REACT_111217. Metabolism.
Gene expression databases
ArrayExpress	Q9Y4X1.
Bgee	Q9Y4X1.
CleanEx	HS_UGT2A1.
Genevestigator	Q9Y4X1.
GermOnline	ENSG00000173610. Homo sapiens.
Family and domain databases
InterPro	IPR002213. UDP_glucos_trans. [Graphical view]
PANTHER	PTHR11926. PTHR11926. 1 hit.
Pfam	PF00201. UDPGT. 1 hit. [Graphical view]
PROSITE	PS00375. UDPGT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChEMBL	CHEMBL1743321.
GenomeRNAi	10941.
NextBio	35534862.
SOURCE	Search...

Entry information

Entry name

UD2A1_HUMAN

Accession

Primary (citable) accession number: Q9Y4X1
Secondary accession number(s): B4E2F4 , D3GER1, D3GER2, E9PDM7, J3KNA3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2003
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 105 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.