##gff-version 3
Q9Y4K4	UniProtKB	Chain	1	846	.	.	.	ID=PRO_0000086282;Note=Mitogen-activated protein kinase kinase kinase kinase 5	
Q9Y4K4	UniProtKB	Domain	20	277	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9Y4K4	UniProtKB	Domain	506	819	.	.	.	Note=CNH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00795	
Q9Y4K4	UniProtKB	Region	323	485	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y4K4	UniProtKB	Compositional bias	333	358	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y4K4	UniProtKB	Compositional bias	402	418	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y4K4	UniProtKB	Compositional bias	426	466	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Y4K4	UniProtKB	Active site	140	140	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9Y4K4	UniProtKB	Binding site	26	34	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
Q9Y4K4	UniProtKB	Binding site	49	49	.	.	.	Ontology_term=ECO:0000255,ECO:0000269;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000269|PubMed:9038372;Dbxref=PMID:9038372	
Q9Y4K4	UniProtKB	Modified residue	335	335	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q9Y4K4	UniProtKB	Modified residue	433	433	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BPM2	
Q9Y4K4	UniProtKB	Natural variant	41	41	.	.	.	ID=VAR_057102;Note=H->Y;Dbxref=dbSNP:rs34726242	
Q9Y4K4	UniProtKB	Natural variant	334	334	.	.	.	ID=VAR_040747;Note=A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs12881869,PMID:17344846	
Q9Y4K4	UniProtKB	Natural variant	407	407	.	.	.	ID=VAR_040748;Note=P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs34818002,PMID:17344846	
Q9Y4K4	UniProtKB	Natural variant	446	446	.	.	.	ID=VAR_040749;Note=I->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55815015,PMID:17344846	
Q9Y4K4	UniProtKB	Natural variant	473	473	.	.	.	ID=VAR_040750;Note=K->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9038372;Dbxref=dbSNP:rs35768475,PMID:9038372	
Q9Y4K4	UniProtKB	Natural variant	552	552	.	.	.	ID=VAR_040751;Note=R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55997280,PMID:17344846	
Q9Y4K4	UniProtKB	Natural variant	633	633	.	.	.	ID=VAR_040752;Note=T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs17780143,PMID:17344846	
Q9Y4K4	UniProtKB	Mutagenesis	49	49	.	.	.	Note=Loss of kinase activity and ability to activate JNK family. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9038372;Dbxref=PMID:9038372	
Q9Y4K4	UniProtKB	Sequence conflict	569	569	.	.	.	Note=V->E