Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9Y4G6

- TLN2_HUMAN

UniProt

Q9Y4G6 - TLN2_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Talin-2

Gene

TLN2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).By similarity

GO - Molecular functioni

  1. actin binding Source: UniProtKB
  2. structural constituent of cytoskeleton Source: InterPro
  3. structural molecule activity Source: UniProtKB

GO - Biological processi

  1. cell adhesion Source: UniProtKB
  2. cell-cell junction assembly Source: UniProtKB
  3. cytoskeletal anchoring at plasma membrane Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Talin-2
Gene namesi
Name:TLN2
Synonyms:KIAA0320
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:15447. TLN2.

Subcellular locationi

GO - Cellular componenti

  1. actin cytoskeleton Source: UniProtKB
  2. cell-cell junction Source: UniProtKB
  3. cytoplasm Source: UniProtKB-KW
  4. fascia adherens Source: Ensembl
  5. focal adhesion Source: UniProtKB
  6. plasma membrane Source: UniProtKB-KW
  7. ruffle Source: InterPro
  8. synapse Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Cytoskeleton, Membrane, Synapse

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37958.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 25422542Talin-2PRO_0000219431Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1665 – 16651PhosphotyrosineBy similarity
Modified residuei1843 – 18431Phosphothreonine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9Y4G6.
PaxDbiQ9Y4G6.
PRIDEiQ9Y4G6.

PTM databases

PhosphoSiteiQ9Y4G6.

Expressioni

Gene expression databases

BgeeiQ9Y4G6.
CleanExiHS_TLN2.
ExpressionAtlasiQ9Y4G6. baseline and differential.
GenevestigatoriQ9Y4G6.

Organism-specific databases

HPAiCAB017194.

Interactioni

Subunit structurei

Interacts directly with PIP5K1C.

Binary interactionsi

WithEntry#Exp.IntActNotes
ABL1P005193EBI-1220811,EBI-375543
ITGB2P051075EBI-1220811,EBI-300173

Protein-protein interaction databases

BioGridi123717. 9 interactions.
DIPiDIP-17039N.
IntActiQ9Y4G6. 6 interactions.
MINTiMINT-5005773.
STRINGi9606.ENSP00000303476.

Structurei

3D structure databases

ProteinModelPortaliQ9Y4G6.
SMRiQ9Y4G6. Positions 1-408, 488-914, 916-1046, 1048-1359, 1361-1974, 1976-2292, 2297-2479, 2496-2529.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini88 – 406319FERMPROSITE-ProRule annotationAdd
BLAST
Domaini2294 – 2533240I/LWEQPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni312 – 40695Interaction with PIP5K1CBy similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi861 – 1193333Ala-richAdd
BLAST

Sequence similaritiesi

Contains 1 FERM domain.PROSITE-ProRule annotation
Contains 1 I/LWEQ domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG324465.
GeneTreeiENSGT00550000074542.
HOGENOMiHOG000006734.
HOVERGENiHBG023870.
InParanoidiQ9Y4G6.
KOiK06271.
OMAiGVMENSK.
OrthoDBiEOG7TBC1J.
PhylomeDBiQ9Y4G6.
TreeFamiTF314677.

Family and domain databases

Gene3Di1.20.1410.10. 2 hits.
1.20.1420.10. 1 hit.
1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR019749. Band_41_domain.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR002558. ILWEQ_dom.
IPR002404. Insln_rcpt_S1.
IPR011993. PH_like_dom.
IPR015711. Talin-2.
IPR015224. Talin_cent.
IPR029071. Ubiquitin-rel_dom.
IPR015009. Vinculin-bd_dom.
IPR006077. Vinculin/catenin.
[Graphical view]
PANTHERiPTHR19981:SF15. PTHR19981:SF15. 1 hit.
PfamiPF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF01608. I_LWEQ. 1 hit.
PF02174. IRS. 1 hit.
PF09141. Talin_middle. 1 hit.
PF08913. VBS. 1 hit.
[Graphical view]
ProDomiPD011820. ILWEQ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00295. B41. 1 hit.
SM00307. ILWEQ. 1 hit.
[Graphical view]
SUPFAMiSSF109880. SSF109880. 1 hit.
SSF109885. SSF109885. 4 hits.
SSF47031. SSF47031. 1 hit.
SSF47220. SSF47220. 5 hits.
SSF54236. SSF54236. 1 hit.
PROSITEiPS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
PS50945. I_LWEQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Y4G6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVALSLKICV RHCNVVKTMQ FEPSTAVYDA CRVIRERVPE AQTGQASDYG
60 70 80 90 100
LFLSDEDPRK GIWLEAGRTL DYYMLRNGDI LEYKKKQRPQ KIRMLDGSVK
110 120 130 140 150
TVMVDDSKTV GELLVTICSR IGITNYEEYS LIQETIEEKK EEGTGTLKKD
160 170 180 190 200
RTLLRDERKM EKLKAKLHTD DDLNWLDHSR TFREQGVDEN ETLLLRRKFF
210 220 230 240 250
YSDQNVDSRD PVQLNLLYVQ ARDDILNGSH PVSFEKACEF GGFQAQIQFG
260 270 280 290 300
PHVEHKHKPG FLDLKEFLPK EYIKQRGAEK RIFQEHKNCG EMSEIEAKVK
310 320 330 340 350
YVKLARSLRT YGVSFFLVKE KMKGKNKLVP RLLGITKDSV MRVDEKTKEV
360 370 380 390 400
LQEWPLTTVK RWAASPKSFT LDFGEYQESY YSVQTTEGEQ ISQLIAGYID
410 420 430 440 450
IILKKKQSKD RFGLEGDEES TMLEESVSPK KSTILQQQFN RTGKAEHGSV
460 470 480 490 500
ALPAVMRSGS SGPETFNVGS MPSPQQQVMV GQMHRGHMPP LTSAQQALMG
510 520 530 540 550
TINTSMHAVQ QAQDDLSELD SLPPLGQDMA SRVWVQNKVD ESKHEIHSQV
560 570 580 590 600
DAITAGTASV VNLTAGDPAD TDYTAVGCAI TTISSNLTEM SKGVKLLAAL
610 620 630 640 650
MDDEVGSGED LLRAARTLAG AVSDLLKAVQ PTSGEPRQTV LTAAGSIGQA
660 670 680 690 700
SGDLLRQIGE NETDERFQDV LMSLAKAVAN AAAMLVLKAK NVAQVAEDTV
710 720 730 740 750
LQNRVIAAAT QCALSTSQLV ACAKVVSPTI SSPVCQEQLI EAGKLVDRSV
760 770 780 790 800
ENCVRACQAA TTDSELLKQV SAAASVVSQA LHDLLQHVRQ FASRGEPIGR
810 820 830 840 850
YDQATDTIMC VTESIFSSMG DAGEMVRQAR VLAQATSDLV NAMRSDAEAE
860 870 880 890 900
IDMENSKKLL AAAKLLADST ARMVEAAKGA AANPENEDQQ QRLREAAEGL
910 920 930 940 950
RVATNAAAQN AIKKKIVNRL EVAAKQAAAA ATQTIAASQN AAVSNKNPAA
960 970 980 990 1000
QQQLVQSCKA VADHIPQLVQ GVRGSQAQAE DLSAQLALII SSQNFLQPGS
1010 1020 1030 1040 1050
KMVSSAKAAV PTVSDQAAAM QLSQCAKNLA TSLAELRTAS QKAHEACGPM
1060 1070 1080 1090 1100
EIDSALNTVQ TLKNELQDAK MAAVESQLKP LPGETLEKCA QDLGSTSKAV
1110 1120 1130 1140 1150
GSSMAQLLTC AAQGNEHYTG VAARETAQAL KTLAQAARGV AASTTDPAAA
1160 1170 1180 1190 1200
HAMLDSARDV MEGSAMLIQE AKQALIAPGD AERQQRLAQV AKAVSHSLNN
1210 1220 1230 1240 1250
CVNCLPGQKD VDVALKSIGE SSKKLLVDSL PPSTKPFQEA QSELNQAAAD
1260 1270 1280 1290 1300
LNQSAGEVVH ATRGQSGELA AASGKFSDDF DEFLDAGIEM AGQAQTKEDQ
1310 1320 1330 1340 1350
IQVIGNLKNI SMASSKLLLA AKSLSVDPGA PNAKNLLAAA ARAVTESINQ
1360 1370 1380 1390 1400
LITLCTQQAP GQKECDNALR ELETVKGMLD NPNEPVSDLS YFDCIESVME
1410 1420 1430 1440 1450
NSKVLGESMA GISQNAKTGD LPAFGECVGI ASKALCGLTE AAAQAAYLVG
1460 1470 1480 1490 1500
ISDPNSQAGH QGLVDPIQFA RANQAIQMAC QNLVDPGSSP SQVLSAATIV
1510 1520 1530 1540 1550
AKHTSALCNA CRIASSKTAN PVAKRHFVQS AKEVANSTAN LVKTIKALDG
1560 1570 1580 1590 1600
DFSEDNRNKC RIATAPLIEA VENLTAFASN PEFVSIPAQI SSEGSQAQEP
1610 1620 1630 1640 1650
ILVSAKTMLE SSSYLIRTAR SLAINPKDPP TWSVLAGHSH TVSDSIKSLI
1660 1670 1680 1690 1700
TSIRDKAPGQ RECDYSIDGI NRCIRDIEQA SLAAVSQSLA TRDDISVEAL
1710 1720 1730 1740 1750
QEQLTSVVQE IGHLIDPIAT AARGEAAQLG HKVTQLASYF EPLILAAVGV
1760 1770 1780 1790 1800
ASKILDHQQQ MTVLDQTKTL AESALQMLYA AKEGGGNPKA QHTHDAITEA
1810 1820 1830 1840 1850
AQLMKEAVDD IMVTLNEAAS EVGLVGGMVD AIAEAMSKLD EGTPPEPKGT
1860 1870 1880 1890 1900
FVDYQTTVVK YSKAIAVTAQ EMMTKSVTNP EELGGLASQM TSDYGHLAFQ
1910 1920 1930 1940 1950
GQMAAATAEP EEIGFQIRTR VQDLGHGCIF LVQKAGALQV CPTDSYTKRE
1960 1970 1980 1990 2000
LIECARAVTE KVSLVLSALQ AGNKGTQACI TAATAVSGII ADLDTTIMFA
2010 2020 2030 2040 2050
TAGTLNAENS ETFADHRENI LKTAKALVED TKLLVSGAAS TPDKLAQAAQ
2060 2070 2080 2090 2100
SSAATITQLA EVVKLGAASL GSDDPETQVV LINAIKDVAK ALSDLISATK
2110 2120 2130 2140 2150
GAASKPVDDP SMYQLKGAAK VMVTNVTSLL KTVKAVEDEA TRGTRALEAT
2160 2170 2180 2190 2200
IECIKQELTV FQSKDVPEKT SSPEESIRMT KGITMATAKA VAAGNSCRQE
2210 2220 2230 2240 2250
DVIATANLSR KAVSDMLTAC KQASFHPDVS DEVRTRALRF GTECTLGYLD
2260 2270 2280 2290 2300
LLEHVLVILQ KPTPEFKQQL AAFSKRVAGA VTELIQAAEA MKGTEWVDPE
2310 2320 2330 2340 2350
DPTVIAETEL LGAAASIEAA AKKLEQLKPR AKPKQADETL DFEEQILEAA
2360 2370 2380 2390 2400
KSIAAATSAL VKSASAAQRE LVAQGKVGSI PANAADDGQW SQGLISAARM
2410 2420 2430 2440 2450
VAAATSSLCE AANASVQGHA SEEKLISSAK QVAASTAQLL VACKVKADQD
2460 2470 2480 2490 2500
SEAMRRLQAA GNAVKRASDN LVRAAQKAAF GKADDDDVVV KTKFVGGIAQ
2510 2520 2530 2540
IIAAQEEMLK KERELEEARK KLAQIRQQQY KFLPTELRED EG
Length:2,542
Mass (Da):271,613
Last modified:May 5, 2009 - v4
Checksum:i802D50915F4FD4B0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti285 – 2851E → A in AAM73764. (PubMed:12422219)Curated
Sequence conflicti1269 – 12691L → F in AAM73764. (PubMed:12422219)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti340 – 3401V → A.
Corresponds to variant rs11634784 [ dbSNP | Ensembl ].
VAR_055313
Natural varianti1148 – 11481A → S.
Corresponds to variant rs2280279 [ dbSNP | Ensembl ].
VAR_014432
Natural varianti1148 – 11481A → T.
Corresponds to variant rs2280279 [ dbSNP | Ensembl ].
VAR_059136
Natural varianti1877 – 18771V → I.
Corresponds to variant rs7182971 [ dbSNP | Ensembl ].
VAR_055314
Natural varianti2144 – 21441T → I.
Corresponds to variant rs11633796 [ dbSNP | Ensembl ].
VAR_055315
Natural varianti2266 – 22661F → L.
Corresponds to variant rs3816988 [ dbSNP | Ensembl ].
VAR_014433

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF402000 mRNA. Translation: AAM73764.1.
AC068233 Genomic DNA. No translation available.
AC100839 Genomic DNA. No translation available.
AC103740 Genomic DNA. No translation available.
AB002318 mRNA. Translation: BAA20778.2.
CCDSiCCDS32261.1.
RefSeqiNP_055874.2. NM_015059.2.
XP_006720781.1. XM_006720718.1.
UniGeneiHs.569438.
Hs.610975.

Genome annotation databases

EnsembliENST00000306829; ENSP00000303476; ENSG00000171914.
ENST00000561311; ENSP00000453508; ENSG00000171914.
GeneIDi83660.
KEGGihsa:83660.
UCSCiuc002alb.4. human.

Polymorphism databases

DMDMi229463036.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF402000 mRNA. Translation: AAM73764.1 .
AC068233 Genomic DNA. No translation available.
AC100839 Genomic DNA. No translation available.
AC103740 Genomic DNA. No translation available.
AB002318 mRNA. Translation: BAA20778.2 .
CCDSi CCDS32261.1.
RefSeqi NP_055874.2. NM_015059.2.
XP_006720781.1. XM_006720718.1.
UniGenei Hs.569438.
Hs.610975.

3D structure databases

ProteinModelPortali Q9Y4G6.
SMRi Q9Y4G6. Positions 1-408, 488-914, 916-1046, 1048-1359, 1361-1974, 1976-2292, 2297-2479, 2496-2529.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123717. 9 interactions.
DIPi DIP-17039N.
IntActi Q9Y4G6. 6 interactions.
MINTi MINT-5005773.
STRINGi 9606.ENSP00000303476.

PTM databases

PhosphoSitei Q9Y4G6.

Polymorphism databases

DMDMi 229463036.

Proteomic databases

MaxQBi Q9Y4G6.
PaxDbi Q9Y4G6.
PRIDEi Q9Y4G6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000306829 ; ENSP00000303476 ; ENSG00000171914 .
ENST00000561311 ; ENSP00000453508 ; ENSG00000171914 .
GeneIDi 83660.
KEGGi hsa:83660.
UCSCi uc002alb.4. human.

Organism-specific databases

CTDi 83660.
GeneCardsi GC15P062682.
H-InvDB HIX0012315.
HGNCi HGNC:15447. TLN2.
HPAi CAB017194.
MIMi 607349. gene.
neXtProti NX_Q9Y4G6.
PharmGKBi PA37958.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG324465.
GeneTreei ENSGT00550000074542.
HOGENOMi HOG000006734.
HOVERGENi HBG023870.
InParanoidi Q9Y4G6.
KOi K06271.
OMAi GVMENSK.
OrthoDBi EOG7TBC1J.
PhylomeDBi Q9Y4G6.
TreeFami TF314677.

Miscellaneous databases

ChiTaRSi TLN2. human.
GeneWikii TLN2.
GenomeRNAii 83660.
NextBioi 72631.
PROi Q9Y4G6.
SOURCEi Search...

Gene expression databases

Bgeei Q9Y4G6.
CleanExi HS_TLN2.
ExpressionAtlasi Q9Y4G6. baseline and differential.
Genevestigatori Q9Y4G6.

Family and domain databases

Gene3Di 1.20.1410.10. 2 hits.
1.20.1420.10. 1 hit.
1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR019749. Band_41_domain.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR002558. ILWEQ_dom.
IPR002404. Insln_rcpt_S1.
IPR011993. PH_like_dom.
IPR015711. Talin-2.
IPR015224. Talin_cent.
IPR029071. Ubiquitin-rel_dom.
IPR015009. Vinculin-bd_dom.
IPR006077. Vinculin/catenin.
[Graphical view ]
PANTHERi PTHR19981:SF15. PTHR19981:SF15. 1 hit.
Pfami PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF01608. I_LWEQ. 1 hit.
PF02174. IRS. 1 hit.
PF09141. Talin_middle. 1 hit.
PF08913. VBS. 1 hit.
[Graphical view ]
ProDomi PD011820. ILWEQ. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00295. B41. 1 hit.
SM00307. ILWEQ. 1 hit.
[Graphical view ]
SUPFAMi SSF109880. SSF109880. 1 hit.
SSF109885. SSF109885. 4 hits.
SSF47031. SSF47031. 1 hit.
SSF47220. SSF47220. 5 hits.
SSF54236. SSF54236. 1 hit.
PROSITEi PS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
PS50945. I_LWEQ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin."
    Di Paolo G., Pellegrini L., Letinic K., Cestra G., Zoncu R., Voronov S., Chang S., Guo J., Wenk M.R., De Camilli P.
    Nature 420:85-89(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Brain and Skeletal muscle.
  2. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Nakajima D., Ohira M., Seki N., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 610-2542.
    Tissue: Brain.
  5. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1843, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1843, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiTLN2_HUMAN
AccessioniPrimary (citable) accession number: Q9Y4G6
Secondary accession number(s): A6NLB8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: May 5, 2009
Last modified: November 26, 2014
This is version 142 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3