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Q9Y3Q7

- ADA18_HUMAN

UniProt

Q9Y3Q7 - ADA18_HUMAN

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Protein

Disintegrin and metalloproteinase domain-containing protein 18

Gene

ADAM18

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity).By similarity

GO - Molecular functioni

  1. metalloendopeptidase activity Source: InterPro
  2. metallopeptidase activity Source: ProtInc
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. multicellular organismal development Source: UniProtKB-KW
  3. spermatogenesis Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Spermatogenesis

Protein family/group databases

MEROPSiM12.957.

Names & Taxonomyi

Protein namesi
Recommended name:
Disintegrin and metalloproteinase domain-containing protein 18
Short name:
ADAM 18
Alternative name(s):
Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III
Short name:
tMDC III
Gene namesi
Name:ADAM18
Synonyms:TMDC3
ORF Names:UNQ858/PRO1867
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 8

Organism-specific databases

HGNCiHGNC:196. ADAM18.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24513.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence AnalysisAdd
BLAST
Propeptidei17 – 184168Sequence AnalysisPRO_0000029096Add
BLAST
Chaini185 – 739555Disintegrin and metalloproteinase domain-containing protein 18PRO_0000029097Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi36 – 361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi76 – 761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi122 – 1221N-linked (GlcNAc...)Sequence Analysis
Glycosylationi149 – 1491N-linked (GlcNAc...)Sequence Analysis
Glycosylationi156 – 1561N-linked (GlcNAc...)Sequence Analysis
Glycosylationi177 – 1771N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi293 ↔ 376By similarity
Glycosylationi294 – 2941N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi335 ↔ 360By similarity
Disulfide bondi337 ↔ 342By similarity
Glycosylationi359 – 3591N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi450 ↔ 471By similarity
Glycosylationi465 – 4651N-linked (GlcNAc...)Sequence Analysis
Glycosylationi561 – 5611N-linked (GlcNAc...)Sequence Analysis
Glycosylationi611 – 6111N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi624 ↔ 636By similarity
Glycosylationi625 – 6251N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi630 ↔ 642By similarity
Disulfide bondi644 ↔ 653By similarity

Post-translational modificationi

The prodomain and the metalloprotease-like domain are cleaved during the epididymal maturation of the spermatozoa.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9Y3Q7.
PRIDEiQ9Y3Q7.

PTM databases

PhosphoSiteiQ9Y3Q7.

Expressioni

Tissue specificityi

Expressed specifically in testis.

Gene expression databases

BgeeiQ9Y3Q7.
CleanExiHS_ADAM18.
ExpressionAtlasiQ9Y3Q7. baseline and differential.
GenevestigatoriQ9Y3Q7.

Organism-specific databases

HPAiHPA027605.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265707.

Structurei

3D structure databases

ProteinModelPortaliQ9Y3Q7.
SMRiQ9Y3Q7. Positions 184-657.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini177 – 687511ExtracellularSequence AnalysisAdd
BLAST
Topological domaini709 – 73931CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei688 – 70821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini184 – 381198Peptidase M12BPROSITE-ProRule annotationAdd
BLAST
Domaini390 – 47990DisintegrinPROSITE-ProRule annotationAdd
BLAST
Domaini620 – 65435EGF-likeAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi480 – 622143Cys-richAdd
BLAST

Domaini

A tripeptide motif (ECD) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding.By similarity

Sequence similaritiesi

Contains 1 disintegrin domain.PROSITE-ProRule annotation
Contains 1 EGF-like domain.Curated
Contains 1 peptidase M12B domain.PROSITE-ProRule annotation

Keywords - Domaini

EGF-like domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG329803.
GeneTreeiENSGT00760000119181.
HOGENOMiHOG000230883.
HOVERGENiHBG103628.
InParanoidiQ9Y3Q7.
KOiK16909.
OMAiDYMGSEM.
OrthoDBiEOG7W1537.
PhylomeDBiQ9Y3Q7.
TreeFamiTF314733.

Family and domain databases

Gene3Di3.40.390.10. 1 hit.
4.10.70.10. 1 hit.
InterProiIPR006586. ADAM_Cys-rich.
IPR001762. Blood-coag_inhib_Disintegrin.
IPR018358. Disintegrin_CS.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR002870. Peptidase_M12B_N.
[Graphical view]
PfamiPF08516. ADAM_CR. 1 hit.
PF00200. Disintegrin. 1 hit.
PF01562. Pep_M12B_propep. 1 hit.
PF01421. Reprolysin. 1 hit.
[Graphical view]
SMARTiSM00608. ACR. 1 hit.
SM00050. DISIN. 1 hit.
[Graphical view]
SUPFAMiSSF57552. SSF57552. 1 hit.
PROSITEiPS50215. ADAM_MEPRO. 1 hit.
PS00427. DISINTEGRIN_1. 1 hit.
PS50214. DISINTEGRIN_2. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9Y3Q7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFLLLALLTE LGRLQAHEGS EGIFLHVTVP RKIKSNDSEV SERKMIYIIT
60 70 80 90 100
IDGQPYTLHL GKQSFLPQNF LVYTYNETGS LHSVSPYFMM HCHYQGYAAE
110 120 130 140 150
FPNSFVTLSI CSGLRGFLQF ENISYGIEPV ESSARFEHII YQMKNNDPNV
160 170 180 190 200
SILAVNYSHI WQKDQPYKVP LNSQIKNLSK LLPQYLEIYI IVEKALYDYM
210 220 230 240 250
GSEMMAVTQK IVQVIGLVNT MFTQFKLTVI LSSLELWSNE NQISTSGDAD
260 270 280 290 300
DILQRFLAWK RDYLILRPHD IAYLLVYRKH PKYVGATFPG TVCNKSYDAG
310 320 330 340 350
IAMYPDAIGL EGFSVIIAQL LGLNVGLTYD DITQCFCLRA TCIMNHEAVS
360 370 380 390 400
ASGRKIFSNC SMHDYRYFVS KFETKCLQKL SNLQPLHQNQ PVCGNGILES
410 420 430 440 450
NEECDCGNKN ECQFKKCCDY NTCKLKGSVK CGSGPCCTSK CELSIAGTPC
460 470 480 490 500
RKSIDPECDF TEYCNGTSSN CVPDTYALNG RLCKLGTAYC YNGQCQTTDN
510 520 530 540 550
QCAKIFGKGA QGAPFACFKE VNSLHERSEN CGFKNSQPLP CERKDVLCGK
560 570 580 590 600
LACVQPHKNA NKSDAQSTVY SYIQDHVCVS IATGSSMRSD GTDNAYVADG
610 620 630 640 650
TMCGPEMYCV NKTCRKVHLM GYNCNATTKC KGKGICNNFG NCQCFPGHRP
660 670 680 690 700
PDCKFQFGSP GGSIDDGNFQ KSGDFYTEKG YNTHWNNWFI LSFCIFLPFF
710 720 730
IVFTTVIFKR NEISKSCNRE NAEYNRNSSV VSESDDVGH
Length:739
Mass (Da):82,856
Last modified:November 1, 1999 - v1
Checksum:i2D8BE9A975072CDD
GO
Isoform 2 (identifier: Q9Y3Q7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     197-220: Missing.

Show »
Length:715
Mass (Da):80,183
Checksum:iEF8EB71EBA6AB9DB
GO
Isoform 3 (identifier: Q9Y3Q7-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     175-182: IKNLSKLL → VTVIILML
     183-739: Missing.

Note: No experimental confirmation available.

Show »
Length:182
Mass (Da):20,853
Checksum:i8B524D83BC944C8B
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti170 – 1701P → S in a cutaneous metastatic melanoma sample; somatic mutation. 1 Publication
VAR_066312
Natural varianti212 – 2121V → F.
Corresponds to variant rs10093794 [ dbSNP | Ensembl ].
VAR_051588
Natural varianti284 – 2841V → G in a cutaneous metastatic melanoma sample; somatic mutation. 1 Publication
VAR_066313
Natural varianti344 – 3441M → I in a cutaneous metastatic melanoma sample; somatic mutation. 1 Publication
VAR_066314
Natural varianti362 – 3621M → K in a cutaneous metastatic melanoma sample; somatic mutation. 1 Publication
VAR_066315
Natural varianti536 – 5361S → L in a cutaneous metastatic melanoma sample; somatic mutation. 1 Publication
VAR_066316

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei175 – 1828IKNLSKLL → VTVIILML in isoform 3. 1 PublicationVSP_043285
Alternative sequencei183 – 739557Missing in isoform 3. 1 PublicationVSP_043286Add
BLAST
Alternative sequencei197 – 22024Missing in isoform 2. 1 PublicationVSP_012033Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ133004 mRNA. Translation: CAB40812.1.
AY358321 mRNA. Translation: AAQ88687.1.
AK313961 mRNA. Translation: BAG36677.1.
AC109633 Genomic DNA. No translation available.
AC136365 Genomic DNA. No translation available.
BC034624 mRNA. Translation: AAH34624.1.
BC070279 mRNA. Translation: AAH70279.1.
BC121045 mRNA. Translation: AAI21046.1.
CCDSiCCDS55225.1. [Q9Y3Q7-3]
CCDS6113.1. [Q9Y3Q7-1]
RefSeqiNP_001177885.1. NM_001190956.1. [Q9Y3Q7-3]
NP_055052.1. NM_014237.2. [Q9Y3Q7-1]
UniGeneiHs.127930.

Genome annotation databases

EnsembliENST00000265707; ENSP00000265707; ENSG00000168619. [Q9Y3Q7-1]
ENST00000379866; ENSP00000369195; ENSG00000168619. [Q9Y3Q7-2]
ENST00000520772; ENSP00000429908; ENSG00000168619. [Q9Y3Q7-3]
GeneIDi8749.
KEGGihsa:8749.
UCSCiuc003xnh.3. human. [Q9Y3Q7-3]
uc003xni.3. human. [Q9Y3Q7-1]
uc010lwx.3. human. [Q9Y3Q7-2]

Polymorphism databases

DMDMi20137582.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ133004 mRNA. Translation: CAB40812.1 .
AY358321 mRNA. Translation: AAQ88687.1 .
AK313961 mRNA. Translation: BAG36677.1 .
AC109633 Genomic DNA. No translation available.
AC136365 Genomic DNA. No translation available.
BC034624 mRNA. Translation: AAH34624.1 .
BC070279 mRNA. Translation: AAH70279.1 .
BC121045 mRNA. Translation: AAI21046.1 .
CCDSi CCDS55225.1. [Q9Y3Q7-3 ]
CCDS6113.1. [Q9Y3Q7-1 ]
RefSeqi NP_001177885.1. NM_001190956.1. [Q9Y3Q7-3 ]
NP_055052.1. NM_014237.2. [Q9Y3Q7-1 ]
UniGenei Hs.127930.

3D structure databases

ProteinModelPortali Q9Y3Q7.
SMRi Q9Y3Q7. Positions 184-657.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000265707.

Protein family/group databases

MEROPSi M12.957.

PTM databases

PhosphoSitei Q9Y3Q7.

Polymorphism databases

DMDMi 20137582.

Proteomic databases

PaxDbi Q9Y3Q7.
PRIDEi Q9Y3Q7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000265707 ; ENSP00000265707 ; ENSG00000168619 . [Q9Y3Q7-1 ]
ENST00000379866 ; ENSP00000369195 ; ENSG00000168619 . [Q9Y3Q7-2 ]
ENST00000520772 ; ENSP00000429908 ; ENSG00000168619 . [Q9Y3Q7-3 ]
GeneIDi 8749.
KEGGi hsa:8749.
UCSCi uc003xnh.3. human. [Q9Y3Q7-3 ]
uc003xni.3. human. [Q9Y3Q7-1 ]
uc010lwx.3. human. [Q9Y3Q7-2 ]

Organism-specific databases

CTDi 8749.
GeneCardsi GC08P039459.
HGNCi HGNC:196. ADAM18.
HPAi HPA027605.
neXtProti NX_Q9Y3Q7.
PharmGKBi PA24513.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG329803.
GeneTreei ENSGT00760000119181.
HOGENOMi HOG000230883.
HOVERGENi HBG103628.
InParanoidi Q9Y3Q7.
KOi K16909.
OMAi DYMGSEM.
OrthoDBi EOG7W1537.
PhylomeDBi Q9Y3Q7.
TreeFami TF314733.

Miscellaneous databases

ChiTaRSi ADAM18. human.
GeneWikii ADAM18.
GenomeRNAii 8749.
NextBioi 32825.
PROi Q9Y3Q7.

Gene expression databases

Bgeei Q9Y3Q7.
CleanExi HS_ADAM18.
ExpressionAtlasi Q9Y3Q7. baseline and differential.
Genevestigatori Q9Y3Q7.

Family and domain databases

Gene3Di 3.40.390.10. 1 hit.
4.10.70.10. 1 hit.
InterProi IPR006586. ADAM_Cys-rich.
IPR001762. Blood-coag_inhib_Disintegrin.
IPR018358. Disintegrin_CS.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR002870. Peptidase_M12B_N.
[Graphical view ]
Pfami PF08516. ADAM_CR. 1 hit.
PF00200. Disintegrin. 1 hit.
PF01562. Pep_M12B_propep. 1 hit.
PF01421. Reprolysin. 1 hit.
[Graphical view ]
SMARTi SM00608. ACR. 1 hit.
SM00050. DISIN. 1 hit.
[Graphical view ]
SUPFAMi SSF57552. SSF57552. 1 hit.
PROSITEi PS50215. ADAM_MEPRO. 1 hit.
PS00427. DISINTEGRIN_1. 1 hit.
PS50214. DISINTEGRIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the human tMDC III sperm surface protein transcript."
    Hall L., Frayne J., Dimsey E.A.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis.
  4. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
    Tissue: Testis.
  6. "Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma."
    Wei X., Moncada-Pazos A., Cal S., Soria-Valles C., Gartner J., Rudloff U., Lin J.C., Rosenberg S.A., Lopez-Otin C., Samuels Y.
    Hum. Mutat. 32:E2148-E2175(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS SER-170; GLY-284; ILE-344; LYS-362 AND LEU-536.

Entry informationi

Entry nameiADA18_HUMAN
AccessioniPrimary (citable) accession number: Q9Y3Q7
Secondary accession number(s): B2R9Y0
, Q0VAI4, Q6IRW9, Q6UXJ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Peptidase families
    Classification of peptidase families and list of entries
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3