Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9Y3D9 (RT23_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S23, mitochondrial

Short name=MRP-S23
Short name=S23mt
Gene names
Name:MRPS23
ORF Names:CGI-138, HSPC329
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins By similarity.

Subcellular location

Mitochondrion.

Sequence caution

The sequence AAD34133.1 differs from that shown. Reason: Frameshift at position 138.

The sequence AAF29007.1 differs from that shown. Reason: Frameshift at several positions.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 19019028S ribosomal protein S23, mitochondrial
PRO_0000087705

Amino acid modifications

Modified residue1021N6-acetyllysine Ref.8

Experimental info

Sequence conflict111S → C in AAD34133. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9Y3D9 [UniParc].

Last modified May 23, 2003. Version 2.
Checksum: 0A50DEDA9BFB74AF

FASTA19021,771
        10         20         30         40         50         60 
MAGSRLETVG SIFSRTRDLV RAGVLKEKPL WFDVYDAFPP LREPVFQRPR VRYGKAKAPI 

        70         80         90        100        110        120 
QDIWYHEDRI RAKFYSVYGS GQRAFDLFNP NFKSTCQRFV EKYTELQKLG ETDEEKLFVE 

       130        140        150        160        170        180 
TGKALLAEGV ILRRVGEART QHGGSHVSRK SEHLSVRPQT ALEENETQKE VPQDQHLEAP 

       190 
ADQSKGLLPP 

« Hide

References

« Hide 'large scale' references
[1]"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"Human partial CDS from CD34+ stem cells."
Ye M., Zhang Q.-H., Zhou J., Shen Y., Wu X.-Y., Guan Z.Q., Wang L., Fan H.-Y., Mao Y.-F., Dai M., Huang Q.-H., Chen S.-J., Chen Z.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Umbilical cord blood.
[3]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.
[6]"The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders."
Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T.
Genomics 77:65-70(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 77-98.
[7]"A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins."
Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.
J. Biol. Chem. 275:32585-32591(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[8]"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-102, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF151896 mRNA. Translation: AAD34133.1. Frameshift.
AF161447 mRNA. Translation: AAF29007.1. Frameshift.
AK312729 mRNA. Translation: BAG35600.1.
CH471109 Genomic DNA. Translation: EAW94503.1.
BC000242 mRNA. Translation: AAH00242.1.
AB061206 Genomic DNA. Translation: BAB54956.1.
CCDSCCDS11598.1.
RefSeqNP_057154.2. NM_016070.3.
UniGeneHs.5836.

3D structure databases

ProteinModelPortalQ9Y3D9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid119657. 18 interactions.
IntActQ9Y3D9. 7 interactions.
STRING9606.ENSP00000320184.

PTM databases

PhosphoSiteQ9Y3D9.

Polymorphism databases

DMDM31077184.

Proteomic databases

MaxQBQ9Y3D9.
PaxDbQ9Y3D9.
PeptideAtlasQ9Y3D9.
PRIDEQ9Y3D9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000313608; ENSP00000320184; ENSG00000181610.
GeneID51649.
KEGGhsa:51649.
UCSCuc002ivc.3. human.

Organism-specific databases

CTD51649.
GeneCardsGC17M055916.
HGNCHGNC:14509. MRPS23.
HPAHPA023453.
MIM611985. gene.
neXtProtNX_Q9Y3D9.
PharmGKBPA31011.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG81280.
HOGENOMHOG000059557.
HOVERGENHBG044512.
InParanoidQ9Y3D9.
KOK17402.
OMAFSRTRNL.
OrthoDBEOG7TBC3P.
PhylomeDBQ9Y3D9.
TreeFamTF106116.

Gene expression databases

ArrayExpressQ9Y3D9.
BgeeQ9Y3D9.
CleanExHS_MRPS23.
GenevestigatorQ9Y3D9.

Family and domain databases

InterProIPR019520. Ribosomal_S23/Rsm25.
IPR023611. Ribosomal_S23/S25_mit.
[Graphical view]
PANTHERPTHR15925. PTHR15925. 1 hit.
PfamPF10484. MRP-S23. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi51649.
NextBio55600.
PROQ9Y3D9.
SOURCESearch...

Entry information

Entry nameRT23_HUMAN
AccessionPrimary (citable) accession number: Q9Y3D9
Secondary accession number(s): B2R6V3 expand/collapse secondary AC list , Q96Q24, Q9BWH8, Q9P053
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 23, 2003
Last modified: July 9, 2014
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 17

Human chromosome 17: entries, gene names and cross-references to MIM