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Q9Y3D5

- RT18C_HUMAN

UniProt

Q9Y3D5 - RT18C_HUMAN

Protein

28S ribosomal protein S18c, mitochondrial

Gene

MRPS18C

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: UniProtKB

    GO - Biological processi

    1. translation Source: UniProtKB

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    28S ribosomal protein S18c, mitochondrial
    Short name:
    MRP-S18-c
    Short name:
    Mrps18-c
    Short name:
    S18mt-c
    Alternative name(s):
    28S ribosomal protein S18-1, mitochondrial
    Short name:
    MRP-S18-1
    Gene namesi
    Name:MRPS18C
    ORF Names:CGI-134
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:16633. MRPS18C.

    Subcellular locationi

    Mitochondrion 1 Publication

    GO - Cellular componenti

    1. mitochondrial small ribosomal subunit Source: UniProtKB

    Keywords - Cellular componenti

    Mitochondrion

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA31005.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 14228S ribosomal protein S18c, mitochondrialPRO_0000030629
    Transit peptidei1 – ?MitochondrionSequence Analysis

    Proteomic databases

    MaxQBiQ9Y3D5.
    PaxDbiQ9Y3D5.
    PeptideAtlasiQ9Y3D5.
    PRIDEiQ9Y3D5.

    PTM databases

    PhosphoSiteiQ9Y3D5.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9Y3D5.
    BgeeiQ9Y3D5.
    CleanExiHS_MRPS18C.
    GenevestigatoriQ9Y3D5.

    Organism-specific databases

    HPAiHPA050404.

    Interactioni

    Subunit structurei

    Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

    Protein-protein interaction databases

    BioGridi119229. 2 interactions.
    STRINGi9606.ENSP00000295491.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Y3D5.
    SMRiQ9Y3D5. Positions 73-125.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S18P family.By similarity

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG242052.
    HOGENOMiHOG000218466.
    HOVERGENiHBG068938.
    InParanoidiQ9Y3D5.
    KOiK02963.
    OMAiQVTSNED.
    OrthoDBiEOG7JDR1D.
    PhylomeDBiQ9Y3D5.
    TreeFamiTF315059.

    Family and domain databases

    Gene3Di4.10.640.10. 1 hit.
    InterProiIPR001648. Ribosomal_S18.
    IPR018275. Ribosomal_S18_CS.
    [Graphical view]
    PANTHERiPTHR13479. PTHR13479. 1 hit.
    PfamiPF01084. Ribosomal_S18. 1 hit.
    [Graphical view]
    ProDomiPD002239. Ribosomal_S18. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF46911. SSF46911. 1 hit.
    TIGRFAMsiTIGR00165. S18. 1 hit.
    PROSITEiPS00057. RIBOSOMAL_S18. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9Y3D5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAVVAVCGG LGRKKLTHLV TAAVSLTHPG THTVLWRRGC SQQVSSNEDL    50
    PISMENPYKE PLKKCILCGK HVDYKNVQLL SQFVSPFTGC IYGRHITGLC 100
    GKKQKEITKA IKRAQIMGFM PVTYKDPAYL KDPKVCNIRY RE 142
    Length:142
    Mass (Da):15,850
    Last modified:November 1, 1999 - v1
    Checksum:i375E0F8558492E63
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF151892 mRNA. Translation: AAD34129.1.
    BC005186 mRNA. Translation: AAH05186.1.
    CCDSiCCDS3604.1.
    RefSeqiNP_057151.1. NM_016067.2.
    UniGeneiHs.334772.
    Hs.436161.

    Genome annotation databases

    EnsembliENST00000295491; ENSP00000295491; ENSG00000163319.
    GeneIDi51023.
    KEGGihsa:51023.
    UCSCiuc003hor.4. human.

    Polymorphism databases

    DMDMi24212202.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF151892 mRNA. Translation: AAD34129.1 .
    BC005186 mRNA. Translation: AAH05186.1 .
    CCDSi CCDS3604.1.
    RefSeqi NP_057151.1. NM_016067.2.
    UniGenei Hs.334772.
    Hs.436161.

    3D structure databases

    ProteinModelPortali Q9Y3D5.
    SMRi Q9Y3D5. Positions 73-125.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119229. 2 interactions.
    STRINGi 9606.ENSP00000295491.

    PTM databases

    PhosphoSitei Q9Y3D5.

    Polymorphism databases

    DMDMi 24212202.

    Proteomic databases

    MaxQBi Q9Y3D5.
    PaxDbi Q9Y3D5.
    PeptideAtlasi Q9Y3D5.
    PRIDEi Q9Y3D5.

    Protocols and materials databases

    DNASUi 51023.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000295491 ; ENSP00000295491 ; ENSG00000163319 .
    GeneIDi 51023.
    KEGGi hsa:51023.
    UCSCi uc003hor.4. human.

    Organism-specific databases

    CTDi 51023.
    GeneCardsi GC04P084301.
    H-InvDB HIX0034634.
    HGNCi HGNC:16633. MRPS18C.
    HPAi HPA050404.
    MIMi 611983. gene.
    neXtProti NX_Q9Y3D5.
    PharmGKBi PA31005.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG242052.
    HOGENOMi HOG000218466.
    HOVERGENi HBG068938.
    InParanoidi Q9Y3D5.
    KOi K02963.
    OMAi QVTSNED.
    OrthoDBi EOG7JDR1D.
    PhylomeDBi Q9Y3D5.
    TreeFami TF315059.

    Miscellaneous databases

    ChiTaRSi MRPS18C. human.
    GenomeRNAii 51023.
    NextBioi 53554.
    PROi Q9Y3D5.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9Y3D5.
    Bgeei Q9Y3D5.
    CleanExi HS_MRPS18C.
    Genevestigatori Q9Y3D5.

    Family and domain databases

    Gene3Di 4.10.640.10. 1 hit.
    InterProi IPR001648. Ribosomal_S18.
    IPR018275. Ribosomal_S18_CS.
    [Graphical view ]
    PANTHERi PTHR13479. PTHR13479. 1 hit.
    Pfami PF01084. Ribosomal_S18. 1 hit.
    [Graphical view ]
    ProDomi PD002239. Ribosomal_S18. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF46911. SSF46911. 1 hit.
    TIGRFAMsi TIGR00165. S18. 1 hit.
    PROSITEi PS00057. RIBOSOMAL_S18. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
      Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
      Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.
    3. "The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present."
      Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.
      J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION.
    4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRT18C_HUMAN
    AccessioniPrimary (citable) accession number: Q9Y3D5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2002
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 114 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Ribosomal proteins
      Ribosomal proteins families and list of entries
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3