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Q9Y3A5

- SBDS_HUMAN

UniProt

Q9Y3A5 - SBDS_HUMAN

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Protein

Ribosome maturation protein SBDS

Gene

SBDS

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.4 Publications

GO - Molecular functioni

  1. microtubule binding Source: UniProtKB
  2. poly(A) RNA binding Source: UniProtKB
  3. ribosome binding Source: UniProtKB
  4. rRNA binding Source: UniProtKB

GO - Biological processi

  1. bone marrow development Source: UniProtKB
  2. bone mineralization Source: UniProtKB
  3. cell proliferation Source: UniProtKB
  4. inner cell mass cell proliferation Source: Ensembl
  5. leukocyte chemotaxis Source: UniProtKB
  6. mature ribosome assembly Source: UniProtKB
  7. mitotic spindle stabilization Source: UniProtKB
  8. ribosomal large subunit biogenesis Source: RefGenome
  9. rRNA processing Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome maturation protein SBDS
Alternative name(s):
Shwachman-Bodian-Diamond syndrome protein
Gene namesi
Name:SBDS
ORF Names:CGI-97
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:19440. SBDS.

Subcellular locationi

Cytoplasm. Nucleusnucleolus. Nucleusnucleoplasm. Cytoplasmcytoskeletonspindle
Note: Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 and PubMed:17475909). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in the nucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center during interphase (PubMed:19759903).1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. nucleolus Source: UniProtKB
  3. nucleus Source: UniProtKB
  4. spindle pole Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

Pathology & Biotechi

Involvement in diseasei

Shwachman-Diamond syndrome (SDS) [MIM:260400]: Autosomal recessive disorder characterized by pancreatic exocrine insufficiency, hematologic dysfunction, and skeletal abnormalities.2 Publications
Note: The disease is caused by mutations affecting the gene represented in this entry.
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti8 – 81N → K in SDS. 1 Publication
Corresponds to variant rs28942099 [ dbSNP | Ensembl ].
VAR_015390
Natural varianti33 – 331K → T in SDS. 1 Publication
VAR_071673
Natural varianti44 – 441E → G in SDS. 1 Publication
VAR_015391
Natural varianti67 – 671K → E in SDS. 1 Publication
VAR_015392
Natural varianti87 – 871I → S in SDS. 1 Publication
VAR_015393
Natural varianti126 – 1261R → T in SDS; strongly reduced release of EIF6 from pre-60S ribosome subunits. 1 Publication
VAR_015394
Natural varianti169 – 1691R → C in SDS. 1 Publication
VAR_015395
Natural varianti212 – 2121I → T in SDS. 1 Publication
Corresponds to variant rs79344818 [ dbSNP | Ensembl ].
VAR_015396

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi151 – 1511K → N: Strongly reduced release of EIF6 from pre-60S ribosome subunits. 1 Publication

Keywords - Diseasei

Disease mutation

Organism-specific databases

MIMi260400. phenotype.
Orphaneti88. Idiopathic aplastic anemia.
811. Shwachman-Diamond syndrome.
PharmGKBiPA134978742.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed3 Publications
Chaini2 – 250249Ribosome maturation protein SBDSPRO_0000123762Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine3 Publications

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ9Y3A5.
PaxDbiQ9Y3A5.
PeptideAtlasiQ9Y3A5.
PRIDEiQ9Y3A5.

PTM databases

PhosphoSiteiQ9Y3A5.

Expressioni

Tissue specificityi

Widely expressed.

Gene expression databases

BgeeiQ9Y3A5.
CleanExiHS_SBDS.
ExpressionAtlasiQ9Y3A5. baseline.
GenevestigatoriQ9Y3A5.

Organism-specific databases

HPAiHPA028891.

Interactioni

Subunit structurei

Associates with the 60S ribosomal subunit. Interacts with NPM1, RPA1 and PRKDC. May interact with NIP7.3 Publications

Protein-protein interaction databases

BioGridi119307. 37 interactions.
IntActiQ9Y3A5. 1 interaction.
MINTiMINT-3085538.
STRINGi9606.ENSP00000246868.

Structurei

Secondary structure

1
250
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni6 – 83
Beta strandi14 – 218
Beta strandi26 – 3510
Helixi36 – 405
Helixi47 – 504
Beta strandi51 – 555
Beta strandi56 – 594
Turni60 – 634
Beta strandi64 – 663
Helixi68 – 747
Helixi80 – 8910
Beta strandi90 – 934
Beta strandi97 – 1037
Helixi107 – 11610
Turni122 – 1254
Helixi130 – 14011
Helixi150 – 16415
Beta strandi168 – 1703
Beta strandi174 – 1774
Helixi180 – 1867
Turni187 – 1893
Helixi190 – 1934
Beta strandi196 – 2005
Beta strandi203 – 2053
Beta strandi208 – 2103
Helixi214 – 2163
Helixi217 – 22711
Turni228 – 2314
Beta strandi232 – 2365
Beta strandi240 – 2423

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2KDONMR-A1-250[»]
2L9NNMR-A1-250[»]
ProteinModelPortaliQ9Y3A5.
SMRiQ9Y3A5. Positions 1-250.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9Y3A5.

Family & Domainsi

Sequence similaritiesi

Belongs to the SDO1/SBDS family.Curated

Phylogenomic databases

eggNOGiCOG1500.
GeneTreeiENSGT00390000008135.
HOGENOMiHOG000216685.
HOVERGENiHBG039762.
InParanoidiQ9Y3A5.
KOiK14574.
OMAiRSGIETD.
OrthoDBiEOG7XWPPD.
PhylomeDBiQ9Y3A5.
TreeFamiTF300881.

Family and domain databases

Gene3Di3.30.1250.10. 1 hit.
InterProiIPR018978. Ribosome_mat_SBDS_C.
IPR018023. Ribosome_mat_SBDS_CS.
IPR019783. Ribosome_mat_SBDS_N.
IPR002140. Ribosome_maturation_pr_SBDS.
[Graphical view]
PANTHERiPTHR10927. PTHR10927. 1 hit.
PfamiPF01172. SBDS. 1 hit.
PF09377. SBDS_C. 1 hit.
[Graphical view]
SUPFAMiSSF89895. SSF89895. 1 hit.
TIGRFAMsiTIGR00291. RNA_SBDS. 1 hit.
PROSITEiPS01267. UPF0023. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y3A5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIFTPTNQI RLTNVAVVRM KRAGKRFEIA CYKNKVVGWR SGVEKDLDEV
60 70 80 90 100
LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER
110 120 130 140 150
HTQLEQMFRD IATIVADKCV NPETKRPYTV ILIERAMKDI HYSVKTNKST
160 170 180 190 200
KQQALEVIKQ LKEKMKIERA HMRLRFILPV NEGKKLKEKL KPLIKVIESE
210 220 230 240 250
DYGQQLEIVC LIDPGCFREI DELIKKETKG KGSLEVLNLK DVEEGDEKFE
Length:250
Mass (Da):28,764
Last modified:January 23, 2007 - v4
Checksum:iD35C43003C05F5A7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 433SGV → RAW in AAD34092. (PubMed:10810093)Curated
Sequence conflicti89 – 891T → A in AAD34092. (PubMed:10810093)Curated
Sequence conflicti105 – 1051E → G in AAD34092. (PubMed:10810093)Curated
Sequence conflicti114 – 1141I → F in AAD34092. (PubMed:10810093)Curated
Sequence conflicti126 – 1261R → G in AAD34092. (PubMed:10810093)Curated
Sequence conflicti143 – 1431S → L in AAD34092. (PubMed:10810093)Curated
Sequence conflicti146 – 1461T → P in AAD34092. (PubMed:10810093)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti8 – 81N → K in SDS. 1 Publication
Corresponds to variant rs28942099 [ dbSNP | Ensembl ].
VAR_015390
Natural varianti33 – 331K → T in SDS. 1 Publication
VAR_071673
Natural varianti44 – 441E → G in SDS. 1 Publication
VAR_015391
Natural varianti67 – 671K → E in SDS. 1 Publication
VAR_015392
Natural varianti87 – 871I → S in SDS. 1 Publication
VAR_015393
Natural varianti126 – 1261R → T in SDS; strongly reduced release of EIF6 from pre-60S ribosome subunits. 1 Publication
VAR_015394
Natural varianti169 – 1691R → C in SDS. 1 Publication
VAR_015395
Natural varianti212 – 2121I → T in SDS. 1 Publication
Corresponds to variant rs79344818 [ dbSNP | Ensembl ].
VAR_015396

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY169963 mRNA. Translation: AAN77490.1.
AF151855 mRNA. Translation: AAD34092.1.
AK001779 mRNA. Translation: BAA91905.1.
AK289609 mRNA. Translation: BAF82298.1.
CH471140 Genomic DNA. Translation: EAX07906.1.
BC065700 mRNA. Translation: AAH65700.1.
CCDSiCCDS5537.1.
RefSeqiNP_057122.2. NM_016038.2.
UniGeneiHs.110445.

Genome annotation databases

EnsembliENST00000246868; ENSP00000246868; ENSG00000126524.
GeneIDi51119.
KEGGihsa:51119.
UCSCiuc003tvm.1. human.

Polymorphism databases

DMDMi28380824.

Cross-referencesi

Web resourcesi

SBDSbase

SBDS mutation db

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY169963 mRNA. Translation: AAN77490.1 .
AF151855 mRNA. Translation: AAD34092.1 .
AK001779 mRNA. Translation: BAA91905.1 .
AK289609 mRNA. Translation: BAF82298.1 .
CH471140 Genomic DNA. Translation: EAX07906.1 .
BC065700 mRNA. Translation: AAH65700.1 .
CCDSi CCDS5537.1.
RefSeqi NP_057122.2. NM_016038.2.
UniGenei Hs.110445.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2KDO NMR - A 1-250 [» ]
2L9N NMR - A 1-250 [» ]
ProteinModelPortali Q9Y3A5.
SMRi Q9Y3A5. Positions 1-250.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119307. 37 interactions.
IntActi Q9Y3A5. 1 interaction.
MINTi MINT-3085538.
STRINGi 9606.ENSP00000246868.

PTM databases

PhosphoSitei Q9Y3A5.

Polymorphism databases

DMDMi 28380824.

Proteomic databases

MaxQBi Q9Y3A5.
PaxDbi Q9Y3A5.
PeptideAtlasi Q9Y3A5.
PRIDEi Q9Y3A5.

Protocols and materials databases

DNASUi 51119.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000246868 ; ENSP00000246868 ; ENSG00000126524 .
GeneIDi 51119.
KEGGi hsa:51119.
UCSCi uc003tvm.1. human.

Organism-specific databases

CTDi 51119.
GeneCardsi GC07M066452.
GeneReviewsi SBDS.
HGNCi HGNC:19440. SBDS.
HPAi HPA028891.
MIMi 260400. phenotype.
607444. gene.
neXtProti NX_Q9Y3A5.
Orphaneti 88. Idiopathic aplastic anemia.
811. Shwachman-Diamond syndrome.
PharmGKBi PA134978742.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1500.
GeneTreei ENSGT00390000008135.
HOGENOMi HOG000216685.
HOVERGENi HBG039762.
InParanoidi Q9Y3A5.
KOi K14574.
OMAi RSGIETD.
OrthoDBi EOG7XWPPD.
PhylomeDBi Q9Y3A5.
TreeFami TF300881.

Miscellaneous databases

ChiTaRSi SBDS. human.
EvolutionaryTracei Q9Y3A5.
GeneWikii SBDS.
GenomeRNAii 51119.
NextBioi 53897.
PROi Q9Y3A5.
SOURCEi Search...

Gene expression databases

Bgeei Q9Y3A5.
CleanExi HS_SBDS.
ExpressionAtlasi Q9Y3A5. baseline.
Genevestigatori Q9Y3A5.

Family and domain databases

Gene3Di 3.30.1250.10. 1 hit.
InterProi IPR018978. Ribosome_mat_SBDS_C.
IPR018023. Ribosome_mat_SBDS_CS.
IPR019783. Ribosome_mat_SBDS_N.
IPR002140. Ribosome_maturation_pr_SBDS.
[Graphical view ]
PANTHERi PTHR10927. PTHR10927. 1 hit.
Pfami PF01172. SBDS. 1 hit.
PF09377. SBDS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF89895. SSF89895. 1 hit.
TIGRFAMsi TIGR00291. RNA_SBDS. 1 hit.
PROSITEi PS01267. UPF0023. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Mutations in SBDS are associated with Shwachman-Diamond syndrome."
    Boocock G.R.B., Morrison J.A., Popovic M., Richards N., Ellis L., Durie P.R., Rommens J.M.
    Nat. Genet. 33:97-101(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANTS SDS LYS-8; GLY-44; GLU-67; SER-87; THR-126; CYS-169 AND THR-212.
  2. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
    Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
    Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain cortex and Ovarian carcinoma.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PNS.
  6. Bienvenut W.V., Claeys D.
    Submitted (NOV-2005) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 2-19, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Platelet.
  7. "The Shwachman-Diamond SBDS protein localizes to the nucleolus."
    Austin K.M., Leary R.J., Shimamura A.
    Blood 106:1253-1258(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  8. "The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA."
    Ganapathi K.A., Austin K.M., Lee C.S., Dias A., Malsch M.M., Reed R., Shimamura A.
    Blood 110:1458-1465(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH NPM1 AND THE 60S RIBOSOMAL SUBUNIT, SUBCELLULAR LOCATION.
  9. "The Shwachman-Bodian-Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels."
    Hesling C., Oliveira C.C., Castilho B.A., Zanchin N.I.
    Exp. Cell Res. 313:4180-4195(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH NIP7.
  10. "Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses."
    Ball H.L., Zhang B., Riches J.J., Gandhi R., Li J., Rommens J.M., Myers J.S.
    Hum. Mol. Genet. 18:3684-3695(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH RPA1; PRKDC AND THE 60S RIBOSOME SUBUNIT.
  11. "SBDS expression and localization at the mitotic spindle in human myeloid progenitors."
    Orelio C., Verkuijlen P., Geissler J., van den Berg T.K., Kuijpers T.W.
    PLoS ONE 4:E7084-E7084(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. Cited for: STRUCTURE BY NMR, RNA-BINDING.
  16. Cited for: STRUCTURE BY NMR, FUNCTION, CHARACTERIZATION OF VARIANT SDS THR-126, MUTAGENESIS OF LYS-151.
  17. Cited for: VARIANT SDS THR-33.

Entry informationi

Entry nameiSBDS_HUMAN
AccessioniPrimary (citable) accession number: Q9Y3A5
Secondary accession number(s): A8K0P4, Q96FX0, Q9NV53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 132 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3