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Protein

Translation machinery-associated protein 7

Gene

TMA7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Translation machinery-associated protein 7
Alternative name(s):
Coiled-coil domain-containing protein 72
Gene namesi
Name:TMA7
Synonyms:CCDC72
ORF Names:HSPC016, HSPC330
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000232112.3.
HGNCiHGNC:26932. TMA7.
MIMi615808. gene.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000232112.
PharmGKBiPA143485423.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002356811 – 64Translation machinery-associated protein 7Add BLAST64

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei61ADP-ribosylserine1 Publication1

Keywords - PTMi

ADP-ribosylation

Proteomic databases

EPDiQ9Y2S6.
MaxQBiQ9Y2S6.
PaxDbiQ9Y2S6.
PeptideAtlasiQ9Y2S6.
PRIDEiQ9Y2S6.
TopDownProteomicsiQ9Y2S6.

PTM databases

iPTMnetiQ9Y2S6.
PhosphoSitePlusiQ9Y2S6.

Expressioni

Tissue specificityi

Expressed in dermal papilla cells with aggregative behavior.1 Publication

Gene expression databases

BgeeiENSG00000232112.
CleanExiHS_CCDC72.
ExpressionAtlasiQ9Y2S6. baseline and differential.
GenevisibleiQ9Y2S6. HS.

Organism-specific databases

HPAiHPA047397.

Interactioni

Protein-protein interaction databases

BioGridi119505. 4 interactors.
IntActiQ9Y2S6. 2 interactors.
MINTiMINT-3084973.
STRINGi9606.ENSP00000397843.

Structurei

3D structure databases

ProteinModelPortaliQ9Y2S6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili21 – 50Sequence analysisAdd BLAST30

Sequence similaritiesi

Belongs to the TMA7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JP6Z. Eukaryota.
ENOG410ZJ3Y. LUCA.
GeneTreeiENSGT00390000003710.
HOGENOMiHOG000197071.
HOVERGENiHBG081046.
InParanoidiQ9Y2S6.
OMAiGQQGIKK.
TreeFamiTF300250.

Family and domain databases

InterProiView protein in InterPro
IPR015157. TMA7.
PANTHERiPTHR28632. PTHR28632. 1 hit.
PfamiView protein in Pfam
PF09072. TMA7. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Y2S6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGREGGKKK PLKQPKKQAK EMDEEDKAFK QKQKEEQKKL EELKAKAAGK
60
GPLATGGIKK SGKK
Length:64
Mass (Da):7,066
Last modified:November 1, 1999 - v1
Checksum:iE79BA054EC176B74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF077202 mRNA. Translation: AAD26997.1.
AY508979 mRNA. Translation: AAR87665.1.
AY794023 mRNA. Translation: AAV40981.1.
BC080531 mRNA. Translation: AAH80531.1.
AF161448 mRNA. Translation: AAF29008.1.
CCDSiCCDS46823.1.
RefSeqiNP_057017.1. NM_015933.5.
UniGeneiHs.356440.

Genome annotation databases

EnsembliENST00000438607; ENSP00000397843; ENSG00000232112.
GeneIDi51372.
KEGGihsa:51372.
UCSCiuc003cte.2. human.

Similar proteinsi

Entry informationi

Entry nameiTMA7_HUMAN
AccessioniPrimary (citable) accession number: Q9Y2S6
Secondary accession number(s): Q9P052
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: November 1, 1999
Last modified: November 22, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families