Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9Y2R5

- RT17_HUMAN

UniProt

Q9Y2R5 - RT17_HUMAN

Protein

28S ribosomal protein S17, mitochondrial

Gene

MRPS17

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: UniProtKB

    GO - Biological processi

    1. translation Source: UniProtKB

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    28S ribosomal protein S17, mitochondrial
    Short name:
    MRP-S17
    Short name:
    S17mt
    Gene namesi
    Name:MRPS17
    Synonyms:RPMS17
    ORF Names:HSPC011
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:14047. MRPS17.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial small ribosomal subunit Source: UniProtKB

    Keywords - Cellular componenti

    Mitochondrion

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA31002.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 2020MitochondrionSequence AnalysisAdd
    BLAST
    Chaini21 – 13011028S ribosomal protein S17, mitochondrialPRO_0000030623Add
    BLAST

    Proteomic databases

    MaxQBiQ9Y2R5.
    PaxDbiQ9Y2R5.
    PRIDEiQ9Y2R5.

    PTM databases

    PhosphoSiteiQ9Y2R5.

    Expressioni

    Gene expression databases

    BgeeiQ9Y2R5.
    CleanExiHS_MRPS17.
    GenevestigatoriQ9Y2R5.

    Organism-specific databases

    HPAiHPA047159.

    Interactioni

    Subunit structurei

    Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

    Protein-protein interaction databases

    BioGridi119506. 3 interactions.
    IntActiQ9Y2R5. 3 interactions.
    MINTiMINT-3084934.
    STRINGi9606.ENSP00000285298.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Y2R5.
    SMRiQ9Y2R5. Positions 11-88.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S17P family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG5048.
    HOGENOMiHOG000126812.
    HOVERGENiHBG002498.
    InParanoidiQ9Y2R5.
    KOiK02961.
    PhylomeDBiQ9Y2R5.
    TreeFamiTF326484.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_01345_B. Ribosomal_S17_B.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR000266. Ribosomal_S17.
    [Graphical view]
    PfamiPF00366. Ribosomal_S17. 1 hit.
    [Graphical view]
    ProDomiPD001295. Ribosomal_S17. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF50249. SSF50249. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9Y2R5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVVRSSVHA RWIVGKVIGT KMQKTAKVRV TRLVLDPYLL KYFNKRKTYF    50
    AHDALQQCTV GDIVLLRALP VPRAKHVKHE LAEIVFKVGK VIDPVTGKPC 100
    AGTTYLESPL SSETTQLSKN LEELNISSAQ 130
    Length:130
    Mass (Da):14,502
    Last modified:November 1, 1999 - v1
    Checksum:i5346917E78F7C6C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF077035 mRNA. Translation: AAD27768.1.
    AB049950 mRNA. Translation: BAB41003.1.
    BC047445 mRNA. Translation: AAH47445.2.
    BC054031 mRNA. Translation: AAH54031.1.
    CCDSiCCDS5520.1.
    RefSeqiNP_057053.1. NM_015969.2.
    UniGeneiHs.44298.

    Genome annotation databases

    EnsembliENST00000285298; ENSP00000285298; ENSG00000239789.
    GeneIDi51373.
    KEGGihsa:51373.
    UCSCiuc003trd.3. human.

    Polymorphism databases

    DMDMi13633951.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF077035 mRNA. Translation: AAD27768.1 .
    AB049950 mRNA. Translation: BAB41003.1 .
    BC047445 mRNA. Translation: AAH47445.2 .
    BC054031 mRNA. Translation: AAH54031.1 .
    CCDSi CCDS5520.1.
    RefSeqi NP_057053.1. NM_015969.2.
    UniGenei Hs.44298.

    3D structure databases

    ProteinModelPortali Q9Y2R5.
    SMRi Q9Y2R5. Positions 11-88.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119506. 3 interactions.
    IntActi Q9Y2R5. 3 interactions.
    MINTi MINT-3084934.
    STRINGi 9606.ENSP00000285298.

    PTM databases

    PhosphoSitei Q9Y2R5.

    Polymorphism databases

    DMDMi 13633951.

    Proteomic databases

    MaxQBi Q9Y2R5.
    PaxDbi Q9Y2R5.
    PRIDEi Q9Y2R5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000285298 ; ENSP00000285298 ; ENSG00000239789 .
    GeneIDi 51373.
    KEGGi hsa:51373.
    UCSCi uc003trd.3. human.

    Organism-specific databases

    CTDi 51373.
    GeneCardsi GC07P056019.
    HGNCi HGNC:14047. MRPS17.
    HPAi HPA047159.
    MIMi 611980. gene.
    neXtProti NX_Q9Y2R5.
    PharmGKBi PA31002.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5048.
    HOGENOMi HOG000126812.
    HOVERGENi HBG002498.
    InParanoidi Q9Y2R5.
    KOi K02961.
    PhylomeDBi Q9Y2R5.
    TreeFami TF326484.

    Miscellaneous databases

    ChiTaRSi mRpS17. human.
    GeneWikii MRPS17.
    GenomeRNAii 51373.
    NextBioi 54859.
    PROi Q9Y2R5.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9Y2R5.
    CleanExi HS_MRPS17.
    Genevestigatori Q9Y2R5.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_01345_B. Ribosomal_S17_B.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR000266. Ribosomal_S17.
    [Graphical view ]
    Pfami PF00366. Ribosomal_S17. 1 hit.
    [Graphical view ]
    ProDomi PD001295. Ribosomal_S17. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."
      Mao M., Fu G., Wu J.-S., Zhang Q.-H., Zhou J., Kan L.-X., Huang Q.-H., He K.-L., Gu B.-W., Han Z.-G., Shen Y., Gu J., Yu Y.-P., Xu S.-H., Wang Y.-X., Chen S.-J., Chen Z.
      Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Umbilical cord blood.
    2. "Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit."
      Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
      J. Biol. Chem. 276:33181-33195(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain and Uterus.
    4. "The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present."
      Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.
      J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiRT17_HUMAN
    AccessioniPrimary (citable) accession number: Q9Y2R5
    Secondary accession number(s): Q86X15
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 27, 2001
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 125 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Ribosomal proteins
      Ribosomal proteins families and list of entries
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3