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Q9Y2R5

- RT17_HUMAN

UniProt

Q9Y2R5 - RT17_HUMAN

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Protein
28S ribosomal protein S17, mitochondrial
Gene
MRPS17, RPMS17, HSPC011
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  1. translation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S17, mitochondrial
Short name:
MRP-S17
Short name:
S17mt
Gene namesi
Name:MRPS17
Synonyms:RPMS17
ORF Names:HSPC011
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:14047. MRPS17.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial small ribosomal subunit Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31002.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2020Mitochondrion Reviewed prediction
Add
BLAST
Chaini21 – 13011028S ribosomal protein S17, mitochondrialUniRule annotation
PRO_0000030623Add
BLAST

Proteomic databases

MaxQBiQ9Y2R5.
PaxDbiQ9Y2R5.
PRIDEiQ9Y2R5.

PTM databases

PhosphoSiteiQ9Y2R5.

Expressioni

Gene expression databases

BgeeiQ9Y2R5.
CleanExiHS_MRPS17.
GenevestigatoriQ9Y2R5.

Organism-specific databases

HPAiHPA047159.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein-protein interaction databases

BioGridi119506. 3 interactions.
IntActiQ9Y2R5. 3 interactions.
MINTiMINT-3084934.
STRINGi9606.ENSP00000285298.

Structurei

3D structure databases

ProteinModelPortaliQ9Y2R5.
SMRiQ9Y2R5. Positions 11-88.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG5048.
HOGENOMiHOG000126812.
HOVERGENiHBG002498.
InParanoidiQ9Y2R5.
KOiK02961.
PhylomeDBiQ9Y2R5.
TreeFamiTF326484.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_01345_B. Ribosomal_S17_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
[Graphical view]
PfamiPF00366. Ribosomal_S17. 1 hit.
[Graphical view]
ProDomiPD001295. Ribosomal_S17. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF50249. SSF50249. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y2R5-1 [UniParc]FASTAAdd to Basket

« Hide

MSVVRSSVHA RWIVGKVIGT KMQKTAKVRV TRLVLDPYLL KYFNKRKTYF    50
AHDALQQCTV GDIVLLRALP VPRAKHVKHE LAEIVFKVGK VIDPVTGKPC 100
AGTTYLESPL SSETTQLSKN LEELNISSAQ 130
Length:130
Mass (Da):14,502
Last modified:November 1, 1999 - v1
Checksum:i5346917E78F7C6C3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF077035 mRNA. Translation: AAD27768.1.
AB049950 mRNA. Translation: BAB41003.1.
BC047445 mRNA. Translation: AAH47445.2.
BC054031 mRNA. Translation: AAH54031.1.
CCDSiCCDS5520.1.
RefSeqiNP_057053.1. NM_015969.2.
UniGeneiHs.44298.

Genome annotation databases

EnsembliENST00000285298; ENSP00000285298; ENSG00000239789.
GeneIDi51373.
KEGGihsa:51373.
UCSCiuc003trd.3. human.

Polymorphism databases

DMDMi13633951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF077035 mRNA. Translation: AAD27768.1 .
AB049950 mRNA. Translation: BAB41003.1 .
BC047445 mRNA. Translation: AAH47445.2 .
BC054031 mRNA. Translation: AAH54031.1 .
CCDSi CCDS5520.1.
RefSeqi NP_057053.1. NM_015969.2.
UniGenei Hs.44298.

3D structure databases

ProteinModelPortali Q9Y2R5.
SMRi Q9Y2R5. Positions 11-88.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119506. 3 interactions.
IntActi Q9Y2R5. 3 interactions.
MINTi MINT-3084934.
STRINGi 9606.ENSP00000285298.

PTM databases

PhosphoSitei Q9Y2R5.

Polymorphism databases

DMDMi 13633951.

Proteomic databases

MaxQBi Q9Y2R5.
PaxDbi Q9Y2R5.
PRIDEi Q9Y2R5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000285298 ; ENSP00000285298 ; ENSG00000239789 .
GeneIDi 51373.
KEGGi hsa:51373.
UCSCi uc003trd.3. human.

Organism-specific databases

CTDi 51373.
GeneCardsi GC07P056019.
HGNCi HGNC:14047. MRPS17.
HPAi HPA047159.
MIMi 611980. gene.
neXtProti NX_Q9Y2R5.
PharmGKBi PA31002.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5048.
HOGENOMi HOG000126812.
HOVERGENi HBG002498.
InParanoidi Q9Y2R5.
KOi K02961.
PhylomeDBi Q9Y2R5.
TreeFami TF326484.

Miscellaneous databases

ChiTaRSi mRpS17. human.
GeneWikii MRPS17.
GenomeRNAii 51373.
NextBioi 54859.
PROi Q9Y2R5.
SOURCEi Search...

Gene expression databases

Bgeei Q9Y2R5.
CleanExi HS_MRPS17.
Genevestigatori Q9Y2R5.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_01345_B. Ribosomal_S17_B.
InterProi IPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
[Graphical view ]
Pfami PF00366. Ribosomal_S17. 1 hit.
[Graphical view ]
ProDomi PD001295. Ribosomal_S17. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF50249. SSF50249. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."
    Mao M., Fu G., Wu J.-S., Zhang Q.-H., Zhou J., Kan L.-X., Huang Q.-H., He K.-L., Gu B.-W., Han Z.-G., Shen Y., Gu J., Yu Y.-P., Xu S.-H., Wang Y.-X., Chen S.-J., Chen Z.
    Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Umbilical cord blood.
  2. "Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit."
    Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
    J. Biol. Chem. 276:33181-33195(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Uterus.
  4. "The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present."
    Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.
    J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiRT17_HUMAN
AccessioniPrimary (citable) accession number: Q9Y2R5
Secondary accession number(s): Q86X15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1999
Last modified: September 3, 2014
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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