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Q9Y2R5 (RT17_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 123. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S17, mitochondrial

Short name=MRP-S17
Short name=S17mt
Gene names
Name:MRPS17
Synonyms:RPMS17
ORF Names:HSPC011
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length130 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Subcellular location

Mitochondrion HAMAP-Rule MF_01345_B.

Sequence similarities

Belongs to the ribosomal protein S17P family.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Non-traceable author statement Ref.4. Source: UniProtKB

   Cellular_componentmitochondrial small ribosomal subunit

Non-traceable author statement Ref.4. Source: UniProtKB

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural constituent of ribosome

Non-traceable author statement Ref.4. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 2020Mitochondrion Potential
Chain21 – 13011028S ribosomal protein S17, mitochondrial HAMAP-Rule MF_01345_B
PRO_0000030623

Sequences

Sequence LengthMass (Da)Tools
Q9Y2R5 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 5346917E78F7C6C3

FASTA13014,502
        10         20         30         40         50         60 
MSVVRSSVHA RWIVGKVIGT KMQKTAKVRV TRLVLDPYLL KYFNKRKTYF AHDALQQCTV 

        70         80         90        100        110        120 
GDIVLLRALP VPRAKHVKHE LAEIVFKVGK VIDPVTGKPC AGTTYLESPL SSETTQLSKN 

       130 
LEELNISSAQ 

« Hide

References

« Hide 'large scale' references
[1]"Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."
Mao M., Fu G., Wu J.-S., Zhang Q.-H., Zhou J., Kan L.-X., Huang Q.-H., He K.-L., Gu B.-W., Han Z.-G., Shen Y., Gu J., Yu Y.-P., Xu S.-H., Wang Y.-X., Chen S.-J., Chen Z.
Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Umbilical cord blood.
[2]"Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit."
Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
J. Biol. Chem. 276:33181-33195(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain and Uterus.
[4]"The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present."
Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.
J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF077035 mRNA. Translation: AAD27768.1.
AB049950 mRNA. Translation: BAB41003.1.
BC047445 mRNA. Translation: AAH47445.2.
BC054031 mRNA. Translation: AAH54031.1.
CCDSCCDS5520.1.
RefSeqNP_057053.1. NM_015969.2.
UniGeneHs.44298.

3D structure databases

ProteinModelPortalQ9Y2R5.
SMRQ9Y2R5. Positions 11-88.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid119506. 4 interactions.
IntActQ9Y2R5. 3 interactions.
MINTMINT-3084934.
STRING9606.ENSP00000285298.

PTM databases

PhosphoSiteQ9Y2R5.

Polymorphism databases

DMDM13633951.

Proteomic databases

MaxQBQ9Y2R5.
PaxDbQ9Y2R5.
PRIDEQ9Y2R5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000285298; ENSP00000285298; ENSG00000239789.
GeneID51373.
KEGGhsa:51373.
UCSCuc003trd.3. human.

Organism-specific databases

CTD51373.
GeneCardsGC07P056019.
HGNCHGNC:14047. MRPS17.
HPAHPA047159.
MIM611980. gene.
neXtProtNX_Q9Y2R5.
PharmGKBPA31002.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG5048.
HOGENOMHOG000126812.
HOVERGENHBG002498.
InParanoidQ9Y2R5.
KOK02961.
PhylomeDBQ9Y2R5.
TreeFamTF326484.

Gene expression databases

BgeeQ9Y2R5.
CleanExHS_MRPS17.
GenevestigatorQ9Y2R5.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_01345_B. Ribosomal_S17_B.
InterProIPR012340. NA-bd_OB-fold.
IPR000266. Ribosomal_S17.
[Graphical view]
PfamPF00366. Ribosomal_S17. 1 hit.
[Graphical view]
ProDomPD001295. Ribosomal_S17. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF50249. SSF50249. 1 hit.
ProtoNetSearch...

Other

ChiTaRSmRpS17. human.
GeneWikiMRPS17.
GenomeRNAi51373.
NextBio54859.
PROQ9Y2R5.
SOURCESearch...

Entry information

Entry nameRT17_HUMAN
AccessionPrimary (citable) accession number: Q9Y2R5
Secondary accession number(s): Q86X15
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1999
Last modified: July 9, 2014
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 7

Human chromosome 7: entries, gene names and cross-references to MIM