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Protein

Netrin-G1

Gene

NTNG1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Neurogenesis

Enzyme and pathway databases

BioCyciZFISH:ENSG00000162631-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Netrin-G1
Alternative name(s):
Laminet-1
Gene namesi
Name:NTNG1
Synonyms:KIAA0976, LMNT1
ORF Names:UNQ571/PRO1133
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:23319. NTNG1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi22854.
MalaCardsiNTNG1.
OpenTargetsiENSG00000162631.
Orphaneti3095. Atypical Rett syndrome.
PharmGKBiPA164742200.

Polymorphism and mutation databases

BioMutaiNTNG1.
DMDMi57015420.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 281 PublicationAdd BLAST28
ChainiPRO_000001709129 – 510Netrin-G1Add BLAST482
PropeptideiPRO_0000017092511 – 539Removed in mature formSequence analysisAdd BLAST29

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 50By similarity
Disulfide bondi72 ↔ 92By similarity
Disulfide bondi80 ↔ 88
Glycosylationi133N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi182 ↔ 206By similarity
Disulfide bondi297 ↔ 306By similarity
Disulfide bondi299 ↔ 315By similarity
Disulfide bondi317 ↔ 326By similarity
Glycosylationi320N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi329 ↔ 354By similarity
Disulfide bondi364 ↔ 373By similarity
Disulfide bondi366 ↔ 384By similarity
Disulfide bondi387 ↔ 396By similarity
Disulfide bondi399 ↔ 417By similarity
Glycosylationi406N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi420 ↔ 432By similarity
Disulfide bondi422 ↔ 438By similarity
Glycosylationi433N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi440 ↔ 449By similarity
Disulfide bondi452 ↔ 462By similarity
Disulfide bondi467 ↔ 480By similarity
Disulfide bondi474 ↔ 486By similarity
Disulfide bondi488 ↔ 497By similarity
Lipidationi510GPI-anchor amidated serineSequence analysis1

Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDbiQ9Y2I2.
PeptideAtlasiQ9Y2I2.
PRIDEiQ9Y2I2.

PTM databases

iPTMnetiQ9Y2I2.
PhosphoSitePlusiQ9Y2I2.

Expressioni

Tissue specificityi

Highly expressed in the thalamus, with very low expression, if any, in other tissues.2 Publications

Gene expression databases

BgeeiENSG00000162631.
CleanExiHS_NTNG1.
ExpressionAtlasiQ9Y2I2. baseline and differential.
GenevisibleiQ9Y2I2. HS.

Interactioni

Subunit structurei

Interacts with NGL1.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
LRRC4Q9HBW12EBI-7444396,EBI-7444327
LRRC4CQ9HCJ24EBI-7444396,EBI-3925442

Protein-protein interaction databases

BioGridi116525. 3 interactors.
IntActiQ9Y2I2. 2 interactors.
MINTiMINT-8300827.
STRINGi9606.ENSP00000359085.

Structurei

Secondary structure

1539
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi33 – 36Combined sources4
Beta strandi45 – 48Combined sources4
Helixi57 – 59Combined sources3
Beta strandi62 – 67Combined sources6
Helixi68 – 70Combined sources3
Beta strandi94 – 96Combined sources3
Turni97 – 99Combined sources3
Helixi103 – 107Combined sources5
Beta strandi118 – 120Combined sources3
Beta strandi132 – 144Combined sources13
Beta strandi148 – 154Combined sources7
Beta strandi158 – 167Combined sources10
Beta strandi173 – 181Combined sources9
Helixi182 – 185Combined sources4
Helixi193 – 195Combined sources3
Turni209 – 211Combined sources3
Beta strandi213 – 215Combined sources3
Turni216 – 219Combined sources4
Beta strandi220 – 223Combined sources4
Helixi226 – 233Combined sources8
Helixi240 – 249Combined sources10
Helixi251 – 256Combined sources6
Beta strandi257 – 268Combined sources12
Beta strandi272 – 275Combined sources4
Helixi281 – 283Combined sources3
Beta strandi287 – 292Combined sources6
Beta strandi294 – 297Combined sources4
Beta strandi300 – 302Combined sources3
Beta strandi306 – 309Combined sources4
Beta strandi312 – 315Combined sources4
Beta strandi321 – 326Combined sources6
Beta strandi345 – 348Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZYJX-ray3.25B/D1-520[»]
ProteinModelPortaliQ9Y2I2.
SMRiQ9Y2I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 296Laminin N-terminalPROSITE-ProRule annotationAdd BLAST251
Domaini297 – 356Laminin EGF-like 1PROSITE-ProRule annotationAdd BLAST60
Domaini364 – 419Laminin EGF-like 2PROSITE-ProRule annotationAdd BLAST56
Domaini420 – 469Laminin EGF-like 3PROSITE-ProRule annotationAdd BLAST50

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni80 – 91NGL discriminant loop IAdd BLAST12
Regioni208 – 214NGL discriminant loop II7
Regioni273 – 275NGL discriminant loop III3

Domaini

The laminin N-terminal domain mediates 1:1 binding to NGL ligand with sub-micromolar affinity. Three NGL-binding loops mediate discrimination for LRRC4C/NGL1 among other NGLs by binding specifically to its LRR repeats. This specificity drives the sorting of a mixed population of molecules into discrete cell surface subdomains.

Sequence similaritiesi

Contains 3 laminin EGF-like domains.PROSITE-ProRule annotation
Contains 1 laminin N-terminal domain.PROSITE-ProRule annotationCurated

Keywords - Domaini

Laminin EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGiKOG1836. Eukaryota.
KOG3512. Eukaryota.
ENOG410XS7U. LUCA.
GeneTreeiENSGT00840000129717.
HOVERGENiHBG052676.
InParanoidiQ9Y2I2.
KOiK07522.
OMAiYCECFGH.
OrthoDBiEOG091G05AV.
PhylomeDBiQ9Y2I2.
TreeFamiTF333945.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
InterProiIPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR008979. Galactose-bd-like.
IPR002049. Laminin_EGF.
IPR008211. Laminin_N.
[Graphical view]
PfamiPF00053. Laminin_EGF. 3 hits.
PF00055. Laminin_N. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 2 hits.
SM00180. EGF_Lam. 3 hits.
SM00136. LamNT. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 3 hits.
PS50026. EGF_3. 1 hit.
PS01248. EGF_LAM_1. 1 hit.
PS50027. EGF_LAM_2. 3 hits.
PS51117. LAMININ_NTER. 1 hit.
[Graphical view]

Sequences (6)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 6 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 3 (identifier: Q9Y2I2-3) [UniParc]FASTAAdd to basket
Also known as: 1A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MYLSRFLSIH ALWVTVSSVM QPYPLVWGHY DLCKTQIYTE EGKVWDYMAC
60 70 80 90 100
QPESTDMTKY LKVKLDPPDI TCGDPPETFC AMGNPYMCNN ECDASTPELA
110 120 130 140 150
HPPELMFDFE GRHPSTFWQS ATWKEYPKPL QVNITLSWSK TIELTDNIVI
160 170 180 190 200
TFESGRPDQM ILEKSLDYGR TWQPYQYYAT DCLDAFHMDP KSVKDLSQHT
210 220 230 240 250
VLEIICTEEY STGYTTNSKI IHFEIKDRFA FFAGPRLRNM ASLYGQLDTT
260 270 280 290 300
KKLRDFFTVT DLRIRLLRPA VGEIFVDELH LARYFYAISD IKVRGRCKCN
310 320 330 340 350
LHATVCVYDN SKLTCECEHN TTGPDCGKCK KNYQGRPWSP GSYLPIPKGT
360 370 380 390 400
ANTCIPSISS IGNCECFGHS NRCSYIDLLN TVICVSCKHN TRGQHCELCR
410 420 430 440 450
LGYFRNASAQ LDDENVCIEC YCNPLGSIHD RCNGSGFCEC KTGTTGPKCD
460 470 480 490 500
ECLPGNSWHY GCQPNVCDNE LLHCQNGGTC HNNVRCLCPA AYTGILCEKL
510 520 530
RCEEAGSCGS DSGQGAPPHG SPALLLLTTL LGTASPLVF
Note: Mostly expressed in adult brain.
Length:539
Mass (Da):60,541
Last modified:January 4, 2005 - v3
Checksum:iC51F872D7A2C60A6
GO
Isoform 2 (identifier: Q9Y2I2-2) [UniParc]FASTAAdd to basket
Also known as: 1F

The sequence of this isoform differs from the canonical sequence as follows:
     363-364: NC → SK
     365-539: Missing.

Show »
Length:364
Mass (Da):41,759
Checksum:iB23DAF4BEDE9271C
GO
Isoform 1 (identifier: Q9Y2I2-1) [UniParc]FASTAAdd to basket
Also known as: 1C

The sequence of this isoform differs from the canonical sequence as follows:
     363-463: Missing.
     464-464: P → T

Note: Hi expression in Expressed in brain and.
Show »
Length:438
Mass (Da):49,340
Checksum:iBBBA6167FAC8DD71
GO
Isoform 4 (identifier: Q9Y2I2-4) [UniParc]FASTAAdd to basket
Also known as: 1D

The sequence of this isoform differs from the canonical sequence as follows:
     364-464: CECFGHSNRC...GNSWHYGCQP → PPKFNRIWPN...SVQVANHKRA

Note: Mostly expressed in kidney, also expressed in adult and fetal brain.
Show »
Length:480
Mass (Da):53,946
Checksum:i9099C3CF4D3F7B86
GO
Isoform 5 (identifier: Q9Y2I2-5) [UniParc]FASTAAdd to basket
Also known as: 1E

The sequence of this isoform differs from the canonical sequence as follows:
     364-385: CECFGHSNRCSYIDLLNTVICV → PPKFNRIWPNISSLEVSNPKQA
     386-464: Missing.

Note: Some expression in fetal brain.
Show »
Length:460
Mass (Da):51,858
Checksum:i8217255F4C8C4C65
GO
Isoform 6 (identifier: Q9Y2I2-6) [UniParc]FASTAAdd to basket
Also known as: 1G

The sequence of this isoform differs from the canonical sequence as follows:
     419-463: Missing.
     464-464: P → A

Note: No experimental confirmation available.
Show »
Length:494
Mass (Da):55,660
Checksum:iF6783893CC0FE0D8
GO

Sequence cautioni

The sequence BAA76820 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6F → S in AAQ88731 (PubMed:12975309).Curated1
Sequence conflicti231F → L in AAQ88731 (PubMed:12975309).Curated1
Sequence conflicti521S → T in AAQ88731 (PubMed:12975309).Curated1
Isoform 2 (identifier: Q9Y2I2-2)
Sequence conflicti364K → KQ in CAD98143 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_012574363 – 463Missing in isoform 1. 2 PublicationsAdd BLAST101
Alternative sequenceiVSP_010429363 – 364NC → SK in isoform 2. 2 Publications2
Alternative sequenceiVSP_012575364 – 464CECFG…YGCQP → PPKFNRIWPNISSLEVSNPK QVAPKLALSTVSSVQVANHK RA in isoform 4. CuratedAdd BLAST101
Alternative sequenceiVSP_012576364 – 385CECFG…TVICV → PPKFNRIWPNISSLEVSNPK QA in isoform 5. CuratedAdd BLAST22
Alternative sequenceiVSP_010430365 – 539Missing in isoform 2. 2 PublicationsAdd BLAST175
Alternative sequenceiVSP_012577386 – 464Missing in isoform 5. CuratedAdd BLAST79
Alternative sequenceiVSP_012578419 – 463Missing in isoform 6. CuratedAdd BLAST45
Alternative sequenceiVSP_012579464P → T in isoform 1. 2 Publications1
Alternative sequenceiVSP_012580464P → A in isoform 6. Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023193 mRNA. Translation: BAA76820.2. Different initiation.
AY358365 mRNA. Translation: AAQ88731.1.
BX538348 mRNA. Translation: CAD98143.1.
AL590427, AL513187 Genomic DNA. Translation: CAH73380.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73381.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73382.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73383.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73384.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73385.1.
AL513187, AL590427 Genomic DNA. Translation: CAH73828.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73829.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73830.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73831.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73832.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73833.1.
BC030220 mRNA. Translation: AAH30220.1.
CCDSiCCDS30785.1. [Q9Y2I2-1]
CCDS44179.1. [Q9Y2I2-4]
CCDS44180.1. [Q9Y2I2-3]
CCDS81354.1. [Q9Y2I2-5]
RefSeqiNP_001106697.1. NM_001113226.2. [Q9Y2I2-3]
NP_001106699.1. NM_001113228.2. [Q9Y2I2-4]
NP_001317594.1. NM_001330665.1.
NP_055732.2. NM_014917.3. [Q9Y2I2-1]
XP_006710519.1. XM_006710456.3. [Q9Y2I2-1]
XP_011539323.1. XM_011541021.1. [Q9Y2I2-3]
XP_016856169.1. XM_017000680.1. [Q9Y2I2-3]
XP_016856170.1. XM_017000681.1. [Q9Y2I2-3]
XP_016856174.1. XM_017000685.1. [Q9Y2I2-1]
XP_016856175.1. XM_017000686.1. [Q9Y2I2-2]
UniGeneiHs.133046.
Hs.732535.

Genome annotation databases

EnsembliENST00000370065; ENSP00000359082; ENSG00000162631. [Q9Y2I2-6]
ENST00000370066; ENSP00000359083; ENSG00000162631. [Q9Y2I2-4]
ENST00000370067; ENSP00000359084; ENSG00000162631. [Q9Y2I2-5]
ENST00000370068; ENSP00000359085; ENSG00000162631. [Q9Y2I2-3]
ENST00000370071; ENSP00000359088; ENSG00000162631. [Q9Y2I2-4]
ENST00000370073; ENSP00000359090; ENSG00000162631. [Q9Y2I2-3]
ENST00000370074; ENSP00000359091; ENSG00000162631. [Q9Y2I2-1]
GeneIDi22854.
KEGGihsa:22854.
UCSCiuc001dvc.4. human. [Q9Y2I2-3]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023193 mRNA. Translation: BAA76820.2. Different initiation.
AY358365 mRNA. Translation: AAQ88731.1.
BX538348 mRNA. Translation: CAD98143.1.
AL590427, AL513187 Genomic DNA. Translation: CAH73380.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73381.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73382.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73383.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73384.1.
AL590427, AC114491, AL513187 Genomic DNA. Translation: CAH73385.1.
AL513187, AL590427 Genomic DNA. Translation: CAH73828.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73829.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73830.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73831.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73832.1.
AL513187, AC114491, AL590427 Genomic DNA. Translation: CAH73833.1.
BC030220 mRNA. Translation: AAH30220.1.
CCDSiCCDS30785.1. [Q9Y2I2-1]
CCDS44179.1. [Q9Y2I2-4]
CCDS44180.1. [Q9Y2I2-3]
CCDS81354.1. [Q9Y2I2-5]
RefSeqiNP_001106697.1. NM_001113226.2. [Q9Y2I2-3]
NP_001106699.1. NM_001113228.2. [Q9Y2I2-4]
NP_001317594.1. NM_001330665.1.
NP_055732.2. NM_014917.3. [Q9Y2I2-1]
XP_006710519.1. XM_006710456.3. [Q9Y2I2-1]
XP_011539323.1. XM_011541021.1. [Q9Y2I2-3]
XP_016856169.1. XM_017000680.1. [Q9Y2I2-3]
XP_016856170.1. XM_017000681.1. [Q9Y2I2-3]
XP_016856174.1. XM_017000685.1. [Q9Y2I2-1]
XP_016856175.1. XM_017000686.1. [Q9Y2I2-2]
UniGeneiHs.133046.
Hs.732535.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZYJX-ray3.25B/D1-520[»]
ProteinModelPortaliQ9Y2I2.
SMRiQ9Y2I2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116525. 3 interactors.
IntActiQ9Y2I2. 2 interactors.
MINTiMINT-8300827.
STRINGi9606.ENSP00000359085.

PTM databases

iPTMnetiQ9Y2I2.
PhosphoSitePlusiQ9Y2I2.

Polymorphism and mutation databases

BioMutaiNTNG1.
DMDMi57015420.

Proteomic databases

PaxDbiQ9Y2I2.
PeptideAtlasiQ9Y2I2.
PRIDEiQ9Y2I2.

Protocols and materials databases

DNASUi22854.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370065; ENSP00000359082; ENSG00000162631. [Q9Y2I2-6]
ENST00000370066; ENSP00000359083; ENSG00000162631. [Q9Y2I2-4]
ENST00000370067; ENSP00000359084; ENSG00000162631. [Q9Y2I2-5]
ENST00000370068; ENSP00000359085; ENSG00000162631. [Q9Y2I2-3]
ENST00000370071; ENSP00000359088; ENSG00000162631. [Q9Y2I2-4]
ENST00000370073; ENSP00000359090; ENSG00000162631. [Q9Y2I2-3]
ENST00000370074; ENSP00000359091; ENSG00000162631. [Q9Y2I2-1]
GeneIDi22854.
KEGGihsa:22854.
UCSCiuc001dvc.4. human. [Q9Y2I2-3]

Organism-specific databases

CTDi22854.
DisGeNETi22854.
GeneCardsiNTNG1.
HGNCiHGNC:23319. NTNG1.
MalaCardsiNTNG1.
MIMi608818. gene.
neXtProtiNX_Q9Y2I2.
OpenTargetsiENSG00000162631.
Orphaneti3095. Atypical Rett syndrome.
PharmGKBiPA164742200.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1836. Eukaryota.
KOG3512. Eukaryota.
ENOG410XS7U. LUCA.
GeneTreeiENSGT00840000129717.
HOVERGENiHBG052676.
InParanoidiQ9Y2I2.
KOiK07522.
OMAiYCECFGH.
OrthoDBiEOG091G05AV.
PhylomeDBiQ9Y2I2.
TreeFamiTF333945.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000162631-MONOMER.

Miscellaneous databases

ChiTaRSiNTNG1. human.
GeneWikiiNTNG1.
GenomeRNAii22854.
PROiQ9Y2I2.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000162631.
CleanExiHS_NTNG1.
ExpressionAtlasiQ9Y2I2. baseline and differential.
GenevisibleiQ9Y2I2. HS.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
InterProiIPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR008979. Galactose-bd-like.
IPR002049. Laminin_EGF.
IPR008211. Laminin_N.
[Graphical view]
PfamiPF00053. Laminin_EGF. 3 hits.
PF00055. Laminin_N. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 2 hits.
SM00180. EGF_Lam. 3 hits.
SM00136. LamNT. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 3 hits.
PS50026. EGF_3. 1 hit.
PS01248. EGF_LAM_1. 1 hit.
PS50027. EGF_LAM_2. 3 hits.
PS51117. LAMININ_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNTNG1_HUMAN
AccessioniPrimary (citable) accession number: Q9Y2I2
Secondary accession number(s): Q5VU86
, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: January 4, 2005
Last modified: November 30, 2016
This is version 147 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.