Q9Y291 (RT33_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
28S ribosomal protein S33, mitochondrial
Short name=MRP-S33
Short name=S33mt

Gene names

Name:	MRPS33
ORF Names:	CGI-139, PTD003

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	106 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
Subcellular location	Mitochondrion Ref.5.

Ontologies

Keywords
Cellular component	Mitochondrion
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Non-traceable author statement Ref.5. Source: UniProtKB
Cellular_component	mitochondrial small ribosomal subunit Non-traceable author statement Ref.5. Source: UniProtKB
Molecular_function	structural constituent of ribosome Non-traceable author statement Ref.5. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 106	106	28S ribosomal protein S33, mitochondrial		PRO_0000087727

Sequences

	Sequence		Length	Mass (Da)
	Q9Y291 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: E755EDAFB6AF6A46	FASTA	106	12,629
	10 20 30 40 50 60 MSSLSEYAFR MSRLSARLFG EVTRPTNSKS MKVVKLFSEL PLAKKKETYD WYPNHHTYAE 70 80 90 100 LMQTLRFLGL YRDEHQDFMD EQKRLKKLRG KEKPKKGEGK RAAKRK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C. Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	Dai M., Peng Y., Song H., Huang Q., Mao Y., Zhang Q., Mao M., Fu G., Luo M., Chen J., Hu R. Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pituitary tumor.
[3]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung.
[5]	"The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present." Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L. J. Biol. Chem. 276:19363-19374(2001) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
[6]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF151897 mRNA. Translation: AAD34134.1. AF078858 mRNA. Translation: AAD44490.1. AC006006 Genomic DNA. Translation: AAD43190.1. BC015462 mRNA. Translation: AAH15462.1.
IPI	IPI00654654.
RefSeq	NP_057155.1. NM_016071.3. NP_444263.1. NM_053035.2.
UniGene	Hs.416207.
3D structure databases
ProteinModelPortal	Q9Y291.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9Y291. 2 interactions.
STRING	9606.ENSP00000320567.
PTM databases
PhosphoSite	Q9Y291.
Polymorphism databases
DMDM	24212388.
Proteomic databases
PaxDb	Q9Y291.
PRIDE	Q9Y291.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000324787; ENSP00000320567; ENSG00000090263. ENST00000393008; ENSP00000376732; ENSG00000090263. ENST00000469351; ENSP00000417287; ENSG00000090263. ENST00000496958; ENSP00000418451; ENSG00000090263.
GeneID	51650.
KEGG	hsa:51650.
UCSC	uc003vwd.4. human.
Organism-specific databases
CTD	51650.
GeneCards	GC07M140705.
HGNC	HGNC:16634. MRPS33.
HPA	HPA030425.
MIM	611993. gene.
neXtProt	NX_Q9Y291.
PharmGKB	PA31020.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG255077.
HOVERGEN	HBG036129.
InParanoid	Q9Y291.
OrthoDB	EOG4SXNF5.
PhylomeDB	Q9Y291.
Gene expression databases
ArrayExpress	Q9Y291.
Bgee	Q9Y291.
CleanEx	HS_MRPS33.
Genevestigator	Q9Y291.
GermOnline	ENSG00000090263. Homo sapiens.
Family and domain databases
InterPro	IPR013219. Ribosomal_S27/S33_mit. [Graphical view]
Pfam	PF08293. MRP-S33. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	51650.
NextBio	55604.
SOURCE	Search...

Entry information

Entry name

RT33_HUMAN

Accession

Primary (citable) accession number: Q9Y291

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2002
Last sequence update:	November 1, 1999
Last modified:	April 3, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.