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Protein

Protein Asterix

Gene

WDR83OS

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000105583-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Asterix
Alternative name(s):
WD repeat domain 83 opposite strand
WDR83 opposite strand
Gene namesi
Name:WDR83OS
Synonyms:C19orf56
ORF Names:CGI-140, My006, PTD008
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:30203. WDR83OS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 62HelicalSequence analysisAdd BLAST23
Transmembranei80 – 96HelicalSequence analysisAdd BLAST17

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105583.
PharmGKBiPA162378666.

Polymorphism and mutation databases

BioMutaiWDR83OS.
DMDMi12585211.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00000716052 – 106Protein AsterixAdd BLAST105

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9Y284.
MaxQBiQ9Y284.
PaxDbiQ9Y284.
PeptideAtlasiQ9Y284.
PRIDEiQ9Y284.
TopDownProteomicsiQ9Y284.

PTM databases

iPTMnetiQ9Y284.
PhosphoSitePlusiQ9Y284.

Expressioni

Gene expression databases

BgeeiENSG00000105583.
CleanExiHS_C19orf56.
ExpressionAtlasiQ9Y284. baseline and differential.
GenevisibleiQ9Y284. HS.

Organism-specific databases

HPAiHPA065685.

Interactioni

Protein-protein interaction databases

BioGridi119522. 2 interactors.
IntActiQ9Y284. 1 interactor.
STRINGi9606.ENSP00000468969.

Structurei

3D structure databases

ProteinModelPortaliQ9Y284.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Asterix family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3462. Eukaryota.
ENOG4111WDX. LUCA.
GeneTreeiENSGT00390000002121.
HOGENOMiHOG000007025.
HOVERGENiHBG000507.
InParanoidiQ9Y284.
OMAiCISFANS.
OrthoDBiEOG091G0W96.
PhylomeDBiQ9Y284.
TreeFamiTF315003.

Family and domain databases

InterProiIPR005351. UPF0139.
[Graphical view]
PANTHERiPTHR13193. PTHR13193. 1 hit.
PfamiPF03669. UPF0139. 1 hit.
[Graphical view]
ProDomiPD073147. UPF0139. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y284-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTNNMSDPR RPNKVLRYKP PPSECNPALD DPTPDYMNLL GMIFSMCGLM
60 70 80 90 100
LKLKWCAWVA VYCSFISFAN SRSSEDTKQM MSSFMLSISA VVMSYLQNPQ

PMTPPW
Length:106
Mass (Da):12,068
Last modified:November 1, 1999 - v1
Checksum:i7D2BDDAF9279071B
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_052498104P → A.Corresponds to variant rs3209404dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF059620 mRNA. Translation: AAG43119.1.
AF078861 mRNA. Translation: AAD44493.1.
AF151898 mRNA. Translation: AAD34135.1.
AK311944 mRNA. Translation: BAG34885.1.
CH471106 Genomic DNA. Translation: EAW84285.1.
BC001192 mRNA. Translation: AAH01192.1.
BC042919 mRNA. Translation: AAH42919.1.
BC061912 mRNA. Translation: AAH61912.1.
CCDSiCCDS12274.1.
RefSeqiNP_057229.1. NM_016145.3.
XP_016882353.1. XM_017026864.1.
UniGeneiHs.108969.
Hs.657204.

Genome annotation databases

EnsembliENST00000596731; ENSP00000468969; ENSG00000105583.
GeneIDi51398.
KEGGihsa:51398.
UCSCiuc002mud.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF059620 mRNA. Translation: AAG43119.1.
AF078861 mRNA. Translation: AAD44493.1.
AF151898 mRNA. Translation: AAD34135.1.
AK311944 mRNA. Translation: BAG34885.1.
CH471106 Genomic DNA. Translation: EAW84285.1.
BC001192 mRNA. Translation: AAH01192.1.
BC042919 mRNA. Translation: AAH42919.1.
BC061912 mRNA. Translation: AAH61912.1.
CCDSiCCDS12274.1.
RefSeqiNP_057229.1. NM_016145.3.
XP_016882353.1. XM_017026864.1.
UniGeneiHs.108969.
Hs.657204.

3D structure databases

ProteinModelPortaliQ9Y284.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119522. 2 interactors.
IntActiQ9Y284. 1 interactor.
STRINGi9606.ENSP00000468969.

PTM databases

iPTMnetiQ9Y284.
PhosphoSitePlusiQ9Y284.

Polymorphism and mutation databases

BioMutaiWDR83OS.
DMDMi12585211.

Proteomic databases

EPDiQ9Y284.
MaxQBiQ9Y284.
PaxDbiQ9Y284.
PeptideAtlasiQ9Y284.
PRIDEiQ9Y284.
TopDownProteomicsiQ9Y284.

Protocols and materials databases

DNASUi51398.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000596731; ENSP00000468969; ENSG00000105583.
GeneIDi51398.
KEGGihsa:51398.
UCSCiuc002mud.3. human.

Organism-specific databases

CTDi51398.
GeneCardsiWDR83OS.
H-InvDBHIX0014794.
HGNCiHGNC:30203. WDR83OS.
HPAiHPA065685.
neXtProtiNX_Q9Y284.
OpenTargetsiENSG00000105583.
PharmGKBiPA162378666.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3462. Eukaryota.
ENOG4111WDX. LUCA.
GeneTreeiENSGT00390000002121.
HOGENOMiHOG000007025.
HOVERGENiHBG000507.
InParanoidiQ9Y284.
OMAiCISFANS.
OrthoDBiEOG091G0W96.
PhylomeDBiQ9Y284.
TreeFamiTF315003.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000105583-MONOMER.

Miscellaneous databases

GenomeRNAii51398.
PROiQ9Y284.

Gene expression databases

BgeeiENSG00000105583.
CleanExiHS_C19orf56.
ExpressionAtlasiQ9Y284. baseline and differential.
GenevisibleiQ9Y284. HS.

Family and domain databases

InterProiIPR005351. UPF0139.
[Graphical view]
PANTHERiPTHR13193. PTHR13193. 1 hit.
PfamiPF03669. UPF0139. 1 hit.
[Graphical view]
ProDomiPD073147. UPF0139. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiASTER_HUMAN
AccessioniPrimary (citable) accession number: Q9Y284
Secondary accession number(s): B2R4T8, Q9BVI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.