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Q9Y284

- ASTER_HUMAN

UniProt

Q9Y284 - ASTER_HUMAN

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Protein

Protein Asterix

Gene

WDR83OS

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Asterix
Alternative name(s):
WD repeat domain 83 opposite strand
WDR83 opposite strand
Gene namesi
Name:WDR83OS
Synonyms:C19orf56
ORF Names:CGI-140, My006, PTD008
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:30203. WDR83OS.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162378666.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 106105Protein AsterixPRO_0000071605Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ9Y284.
PaxDbiQ9Y284.
PRIDEiQ9Y284.

PTM databases

PhosphoSiteiQ9Y284.

Expressioni

Gene expression databases

BgeeiQ9Y284.
CleanExiHS_C19orf56.
GenevestigatoriQ9Y284.

Interactioni

Protein-protein interaction databases

BioGridi119522. 1 interaction.
IntActiQ9Y284. 1 interaction.
STRINGi9606.ENSP00000222190.

Structurei

3D structure databases

ProteinModelPortaliQ9Y284.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6223HelicalSequence AnalysisAdd
BLAST
Transmembranei80 – 9617HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the Asterix family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG317543.
GeneTreeiENSGT00390000002121.
HOGENOMiHOG000007025.
HOVERGENiHBG000507.
InParanoidiQ9Y284.
OMAiLYCSCIS.
OrthoDBiEOG7MSMR4.
PhylomeDBiQ9Y284.
TreeFamiTF315003.

Family and domain databases

InterProiIPR005351. UPF0139.
[Graphical view]
PANTHERiPTHR13193. PTHR13193. 1 hit.
PfamiPF03669. UPF0139. 1 hit.
[Graphical view]
ProDomiPD073147. UPF0139. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Y284-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTNNMSDPR RPNKVLRYKP PPSECNPALD DPTPDYMNLL GMIFSMCGLM
60 70 80 90 100
LKLKWCAWVA VYCSFISFAN SRSSEDTKQM MSSFMLSISA VVMSYLQNPQ

PMTPPW
Length:106
Mass (Da):12,068
Last modified:November 1, 1999 - v1
Checksum:i7D2BDDAF9279071B
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti104 – 1041P → A.
Corresponds to variant rs3209404 [ dbSNP | Ensembl ].
VAR_052498

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF059620 mRNA. Translation: AAG43119.1.
AF078861 mRNA. Translation: AAD44493.1.
AF151898 mRNA. Translation: AAD34135.1.
AK311944 mRNA. Translation: BAG34885.1.
CH471106 Genomic DNA. Translation: EAW84285.1.
BC001192 mRNA. Translation: AAH01192.1.
BC042919 mRNA. Translation: AAH42919.1.
BC061912 mRNA. Translation: AAH61912.1.
CCDSiCCDS12274.1.
RefSeqiNP_057229.1. NM_016145.3.
UniGeneiHs.108969.
Hs.657204.

Genome annotation databases

EnsembliENST00000596731; ENSP00000468969; ENSG00000105583.
GeneIDi51398.
KEGGihsa:51398.
UCSCiuc002mud.2. human.

Polymorphism databases

DMDMi12585211.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF059620 mRNA. Translation: AAG43119.1 .
AF078861 mRNA. Translation: AAD44493.1 .
AF151898 mRNA. Translation: AAD34135.1 .
AK311944 mRNA. Translation: BAG34885.1 .
CH471106 Genomic DNA. Translation: EAW84285.1 .
BC001192 mRNA. Translation: AAH01192.1 .
BC042919 mRNA. Translation: AAH42919.1 .
BC061912 mRNA. Translation: AAH61912.1 .
CCDSi CCDS12274.1.
RefSeqi NP_057229.1. NM_016145.3.
UniGenei Hs.108969.
Hs.657204.

3D structure databases

ProteinModelPortali Q9Y284.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119522. 1 interaction.
IntActi Q9Y284. 1 interaction.
STRINGi 9606.ENSP00000222190.

PTM databases

PhosphoSitei Q9Y284.

Polymorphism databases

DMDMi 12585211.

Proteomic databases

MaxQBi Q9Y284.
PaxDbi Q9Y284.
PRIDEi Q9Y284.

Protocols and materials databases

DNASUi 51398.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000596731 ; ENSP00000468969 ; ENSG00000105583 .
GeneIDi 51398.
KEGGi hsa:51398.
UCSCi uc002mud.2. human.

Organism-specific databases

CTDi 51398.
GeneCardsi GC19M012779.
H-InvDB HIX0014794.
HGNCi HGNC:30203. WDR83OS.
neXtProti NX_Q9Y284.
PharmGKBi PA162378666.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG317543.
GeneTreei ENSGT00390000002121.
HOGENOMi HOG000007025.
HOVERGENi HBG000507.
InParanoidi Q9Y284.
OMAi LYCSCIS.
OrthoDBi EOG7MSMR4.
PhylomeDBi Q9Y284.
TreeFami TF315003.

Miscellaneous databases

GenomeRNAii 51398.
NextBioi 54933.
PROi Q9Y284.

Gene expression databases

Bgeei Q9Y284.
CleanExi HS_C19orf56.
Genevestigatori Q9Y284.

Family and domain databases

InterProi IPR005351. UPF0139.
[Graphical view ]
PANTHERi PTHR13193. PTHR13193. 1 hit.
Pfami PF03669. UPF0139. 1 hit.
[Graphical view ]
ProDomi PD073147. UPF0139. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

  1. Mao Y.M., Xie Y., Zhou Z.X.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Fetal brain.
  2. Song H., Peng Y., Dai M., Huang Q., Mao Y., Zhang Q., Mao M., Fu G., Luo M., Chen J., Hu R.
    Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Pituitary tumor.
  3. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
    Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
    Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Small intestine.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Eye, Liver and Prostate.
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiASTER_HUMAN
AccessioniPrimary (citable) accession number: Q9Y284
Secondary accession number(s): B2R4T8, Q9BVI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3