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Q9Y275 (TN13B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 153. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (8) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tumor necrosis factor ligand superfamily member 13B
Alternative name(s):
B lymphocyte stimulator
Short name=BLyS
B-cell-activating factor
BAFF
Dendritic cell-derived TNF-like molecule
TNF- and APOL-related leukocyte expressed ligand 1
Short name=TALL-1
CD_antigen=CD257
Gene names
Name:TNFSF13B
Synonyms:BAFF, BLYS, TALL1, TNFSF20, ZTNF4
ORF Names:UNQ401/PRO738
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Ref.5 Ref.16

Isoform 2 seems to inhibit isoform 1 secretion and bioactivity By similarity. Ref.5 Ref.16

Isoform 3:Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis. Ref.5 Ref.16

Subunit structure

Homotrimer. Isoform 2 heteromultimerizes with isoform 1, probably limiting the amount of functional isoform 1 on the cell surface. Isoform 3 is unlikely form trimers or bind to BAFF receptors. Ref.4 Ref.5

Subcellular location

Cell membrane; Single-pass type II membrane protein.

Tumor necrosis factor ligand superfamily member 13b, soluble form: Secreted.

Tissue specificity

Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines. Ref.4

Induction

Up-regulated by exposure to IFNG/IFN-gamma. Down-regulated by phorbol myristate acetate/ionomycin treatment.

Post-translational modification

The soluble form derives from the membrane form by proteolytic processing.

Isoform 2 is not efficiently shed from the membrane unlike isoform 1 By similarity.

N-glycosylated.

Sequence similarities

Belongs to the tumor necrosis factor family.

Ontologies

Keywords
   Biological processImmunity
   Cellular componentCell membrane
Membrane
Secreted
   Coding sequence diversityAlternative splicing
Polymorphism
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionCytokine
   PTMCleavage on pair of basic residues
Disulfide bond
Glycoprotein
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processB cell costimulation

Inferred from electronic annotation. Source: Ensembl

B cell homeostasis

Inferred from electronic annotation. Source: Ensembl

T cell costimulation

Inferred from electronic annotation. Source: Ensembl

cell proliferation

Traceable author statement PubMed 10908663. Source: ProtInc

immune response

Inferred from electronic annotation. Source: InterPro

immunoglobulin secretion

Inferred from electronic annotation. Source: Ensembl

positive regulation of B cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of T cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of cell proliferation

Traceable author statement Ref.2. Source: ProtInc

positive regulation of germinal center formation

Inferred from electronic annotation. Source: Ensembl

signal transduction

Traceable author statement PubMed 10908663. Source: ProtInc

   Cellular_componentextracellular space

Inferred from electronic annotation. Source: UniProtKB-KW

integral component of membrane

Non-traceable author statement Ref.4. Source: UniProtKB

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein binding

Inferred from physical interaction PubMed 10801128PubMed 10880535PubMed 10956646. Source: IntAct

receptor binding

Traceable author statement PubMed 10908663. Source: ProtInc

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

TNFRSF13BO148367EBI-519169,EBI-519160

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9Y275-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9Y275-2)

Also known as: DeltaBAFF;

The sequence of this isoform differs from the canonical sequence as follows:
     142-160: Missing.
Isoform 3 (identifier: Q9Y275-3)

Also known as: Delta4BAFF;

The sequence of this isoform differs from the canonical sequence as follows:
     162-164: SYT → FIY
     165-285: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 285285Tumor necrosis factor ligand superfamily member 13b, membrane form
PRO_0000034528
Chain134 – 285152Tumor necrosis factor ligand superfamily member 13b, soluble form
PRO_0000034529

Regions

Topological domain1 – 4646Cytoplasmic Potential
Transmembrane47 – 6721Helical; Signal-anchor for type II membrane protein; Potential
Topological domain68 – 285218Extracellular Potential

Sites

Site133 – 1342Cleavage

Amino acid modifications

Glycosylation1241N-linked (GlcNAc...)
Glycosylation2421N-linked (GlcNAc...) (high mannose)
Disulfide bond232 ↔ 245

Natural variations

Alternative sequence142 – 16019Missing in isoform 2.
VSP_041183
Alternative sequence162 – 1643SYT → FIY in isoform 3.
VSP_047591
Alternative sequence165 – 285121Missing in isoform 3.
VSP_047592
Natural variant1051A → T. Ref.15
Corresponds to variant rs201543678 [ dbSNP | Ensembl ].
VAR_013483

Secondary structure

.......................... 285
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 48ED0D7AB38C8867

FASTA28531,223
        10         20         30         40         50         60 
MDDSTEREQS RLTSCLKKRE EMKLKECVSI LPRKESPSVR SSKDGKLLAA TLLLALLSCC 

        70         80         90        100        110        120 
LTVVSFYQVA ALQGDLASLR AELQGHHAEK LPAGAGAPKA GLEEAPAVTA GLKIFEPPAP 

       130        140        150        160        170        180 
GEGNSSQNSR NKRAVQGPEE TVTQDCLQLI ADSETPTIQK GSYTFVPWLL SFKRGSALEE 

       190        200        210        220        230        240 
KENKILVKET GYFFIYGQVL YTDKTYAMGH LIQRKKVHVF GDELSLVTLF RCIQNMPETL 

       250        260        270        280 
PNNSCYSAGI AKLEEGDELQ LAIPRENAQI SLDGDVTFFG ALKLL 

« Hide

Isoform 2 (DeltaBAFF) [UniParc].

Checksum: 6BD06F90061152C6
Show »

FASTA26629,137
Isoform 3 (Delta4BAFF) [UniParc].

Checksum: F74F5E404973B730
Show »

FASTA16417,578

References

« Hide 'large scale' references
[1]"TALL-1 is a novel member of the TNF family that is down-regulated by mitogens."
Shu H.-B., Hu W.-H., Johnson H.
J. Leukoc. Biol. 65:680-683(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]"BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth."
Schneider P., MacKay F., Steiner V., Hofmann K., Bodmer J.-L., Holler N., Ambrose C., Lawton P., Bixler S., Acha-Orbea H., Valmori D., Romero P., Werner-Favre C., Zubler R.H., Browning J.L., Tschopp J.
J. Exp. Med. 189:1747-1756(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 134-148.
[3]"BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator."
Moore P.A., Belvedere O., Orr A., Pieri K., LaFleur D.W., Feng P., Soppet D., Charters M., Gentz R., Parmelee D., Li Y., Galperina O., Giri J., Roschke V., Nardelli B., Carrell J., Sosnovtseva S., Greenfield W. expand/collapse author list , Ruben S.M., Olsen H.S., Fikes J., Hilbert D.M.
Science 285:260-263(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Tissue: Monocyte and Neutrophil.
[4]"DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF."
Gavin A.L., Ait-Azzouzene D., Ware C.F., Nemazee D.
J. Biol. Chem. 278:38220-38228(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, SUBUNIT.
[5]"The complexity of the BAFF TNF-family members: implications for autoimmunity."
Lahiri A., Pochard P., Le Pottier L., Tobon G.J., Bendaoud B., Youinou P., Pers J.O.
J. Autoimmun. 39:189-198(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), FUNCTION (ISOFORM 3), SUBUNIT, ALTERNATIVE SPLICING.
[6]"Homo sapiens homolog of tumor necrosis factor."
Farrah T., Gross J., Piddington C., O'Hara P.
Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[7]"A novel dendritic cell-derived TNF-like molecule."
Zhang W., Wan T., Yu Y., Cao X.
Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Tissue: Dendritic cell.
[8]Gao H., He F., Li R.
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[9]Livingston R.J., Shaffer T., McFarland I., Nguyen C.P., Stanaway I.B., Rajkumar N., Johnson E.J., da Ponte S.H., Willa H., Ahearn M.O., Bertucci C., Acklestad J., Carroll A., Swanson J., Gildersleeve H.I., Nickerson D.A.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[10]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[11]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[12]"The DNA sequence and analysis of human chromosome 13."
Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[13]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[14]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Tissue: Placenta.
[15]"New polymorphisms of human BLyS gene."
Kawasaki A., Tsuchiya N., Fukazawa T., Hashimoto H., Tokunaga K.
Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-135, VARIANT THR-105.
[16]"APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
Yu G., Boone T., Delaney J., Hawkins N., Kelley M.J., Ramakrishnan M., McCabe S., Qiu W.R., Kornuc M., Xia X.-Z., Guo J., Stolina M., Boyle W.J., Sarosi I., Hsu H., Senaldi G., Theill L.E.
Nat. Immunol. 1:252-256(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[17]"Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands."
Liu Y., Xu L., Opalka N., Kappler J., Shu H.-B., Zhang G.
Cell 108:383-394(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 142-285.
[18]"Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes."
Karpusas M., Cachero T.G., Qian F., Boriack-Sjodin A., Mullen C., Strauch K., Hsu Y.-M., Kalled S.L.
J. Mol. Biol. 315:1145-1154(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 136-285.
[19]"Structural basis of BLyS receptor recognition."
Oren D.A., Li Y., Volovik Y., Morris T.S., Dharia C., Das K., Galperina O., Gentz R., Arnold E.
Nat. Struct. Biol. 9:288-292(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 134-285.
+Additional computationally mapped references.

Web resources

Protein Spotlight

Proteic grace - Issue 77 of December 2006

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF136293 mRNA. Translation: AAD29421.1.
AF116456 mRNA. Translation: AAD25356.1.
AF132600 mRNA. Translation: AAD21092.1.
AY302751 mRNA. Translation: AAP83164.1.
HM636064 mRNA. Translation: ADK91575.1.
AF186114 mRNA. Translation: AAF01432.1.
AF134715 mRNA. Translation: AAF60219.1.
AY129225 mRNA. Translation: AAN08421.1.
EF064706 Genomic DNA. Translation: ABK41889.1.
AY358881 mRNA. Translation: AAQ89240.1.
CR541818 mRNA. Translation: CAG46617.1.
AL157762 Genomic DNA. Translation: CAH70631.1.
CH471085 Genomic DNA. Translation: EAX09099.1.
BC020674 mRNA. Translation: AAH20674.1.
AB073225 Genomic DNA. Translation: BAB90856.1.
CCDSCCDS45067.1. [Q9Y275-2]
CCDS9509.1. [Q9Y275-1]
RefSeqNP_001139117.1. NM_001145645.2. [Q9Y275-2]
NP_006564.1. NM_006573.4. [Q9Y275-1]
UniGeneHs.525157.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1JH5X-ray3.00A/B/C/D/E/F/G/H/I/J142-285[»]
1KD7X-ray2.80A/B/C/K/L/M133-285[»]
1KXGX-ray2.00A/B/C/D/E/F134-285[»]
1OQDX-ray2.60A/B/C/D/E/F/G/H/I/J142-285[»]
1OQEX-ray2.50A/B/C/D/E/F/G/H/I/J142-285[»]
1OSGX-ray3.00A/B/C/D/E/F82-285[»]
1OTZX-ray3.300/1/2/3/4/5/6/7/8/9/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d/e/f/g/h/i/j/k/l/m/n/o/p/q/r/s/t/u/v/w/x138-285[»]
3V56X-ray3.00A/B/C/D/E/F82-285[»]
ProteinModelPortalQ9Y275.
SMRQ9Y275. Positions 142-285.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid115915. 7 interactions.
DIPDIP-6225N.
IntActQ9Y275. 2 interactions.
STRING9606.ENSP00000365048.

Chemistry

ChEMBLCHEMBL2364158.

PTM databases

PhosphoSiteQ9Y275.

Polymorphism databases

DMDM13124573.

Proteomic databases

PaxDbQ9Y275.
PRIDEQ9Y275.

Protocols and materials databases

DNASU10673.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000375887; ENSP00000365048; ENSG00000102524. [Q9Y275-1]
ENST00000430559; ENSP00000389540; ENSG00000102524. [Q9Y275-2]
ENST00000542136; ENSP00000445334; ENSG00000102524. [Q9Y275-3]
GeneID10673.
KEGGhsa:10673.
UCSCuc001vqr.3. human. [Q9Y275-1]
uc010agj.3. human. [Q9Y275-2]

Organism-specific databases

CTD10673.
GeneCardsGC13P108903.
HGNCHGNC:11929. TNFSF13B.
HPACAB009188.
MIM603969. gene.
neXtProtNX_Q9Y275.
PharmGKBPA434.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG47835.
HOGENOMHOG000036810.
HOVERGENHBG061472.
InParanoidQ9Y275.
KOK05476.
OMAILPQKES.
OrthoDBEOG7T4MM3.
PhylomeDBQ9Y275.
TreeFamTF332331.

Gene expression databases

ArrayExpressQ9Y275.
BgeeQ9Y275.
CleanExHS_TNFSF13B.
GenevestigatorQ9Y275.

Family and domain databases

Gene3D2.60.120.40. 1 hit.
InterProIPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamPF00229. TNF. 1 hit.
[Graphical view]
SMARTSM00207. TNF. 1 hit.
[Graphical view]
SUPFAMSSF49842. SSF49842. 1 hit.
PROSITEPS50049. TNF_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9Y275.
GeneWikiB-cell_activating_factor.
GenomeRNAi10673.
NextBio35496036.
PROQ9Y275.
SOURCESearch...

Entry information

Entry nameTN13B_HUMAN
AccessionPrimary (citable) accession number: Q9Y275
Secondary accession number(s): E0ADT7, Q6FHD6, Q7Z5J2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: November 1, 1999
Last modified: July 9, 2014
This is version 153 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 13

Human chromosome 13: entries, gene names and cross-references to MIM

Human cell differentiation molecules

CD nomenclature of surface proteins of human leucocytes and list of entries