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Q9Y271

- CLTR1_HUMAN

UniProt

Q9Y271 - CLTR1_HUMAN

Protein

Cysteinyl leukotriene receptor 1

Gene

CYSLTR1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 119 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

    GO - Molecular functioni

    1. leukotriene receptor activity Source: ProtInc
    2. protein binding Source: IntAct

    GO - Biological processi

    1. calcium ion transport Source: Ensembl
    2. chemotaxis Source: Ensembl
    3. defense response Source: ProtInc
    4. inflammatory response Source: Ensembl
    5. positive regulation of angiogenesis Source: Ensembl
    6. positive regulation of cytosolic calcium ion concentration Source: ProtInc
    7. positive regulation of vasoconstriction Source: Ensembl
    8. respiratory gaseous exchange Source: ProtInc

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_18283. G alpha (q) signalling events.
    REACT_18302. Leukotriene receptors.

    Protein family/group databases

    TCDBi9.A.14.13.2. the g-protein-coupled receptor (gpcr) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cysteinyl leukotriene receptor 1
    Short name:
    CysLTR1
    Alternative name(s):
    Cysteinyl leukotriene D4 receptor
    Short name:
    LTD4 receptor
    G-protein coupled receptor HG55
    HMTMF81
    Gene namesi
    Name:CYSLTR1
    Synonyms:CYSLT1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:17451. CYSLTR1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: ProtInc
    2. membrane Source: ProtInc
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38453.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 337337Cysteinyl leukotriene receptor 1PRO_0000069299Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi6 – 61N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi96 ↔ 173PROSITE-ProRule annotation
    Glycosylationi169 – 1691N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi180 – 1801N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi262 – 2621N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ9Y271.
    PRIDEiQ9Y271.

    PTM databases

    PhosphoSiteiQ9Y271.

    Expressioni

    Tissue specificityi

    Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.

    Gene expression databases

    ArrayExpressiQ9Y271.
    BgeeiQ9Y271.
    CleanExiHS_CYSLTR1.
    GenevestigatoriQ9Y271.

    Organism-specific databases

    HPAiHPA010546.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CYSLTR2Q9NS752EBI-9347754,EBI-3843579

    Protein-protein interaction databases

    IntActiQ9Y271. 1 interaction.
    STRINGi9606.ENSP00000362401.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Y271.
    SMRiQ9Y271. Positions 29-303.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2828ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini50 – 578CytoplasmicSequence Analysis
    Topological domaini79 – 10628ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini128 – 14114CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini163 – 19331ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini215 – 23016CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini252 – 27625ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini298 – 33740CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei29 – 4921Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei58 – 7821Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei107 – 12721Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei142 – 16221Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei194 – 21421Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei231 – 25121Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei277 – 29721Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG119185.
    HOGENOMiHOG000236328.
    HOVERGENiHBG099611.
    InParanoidiQ9Y271.
    KOiK04322.
    OMAiPQDNQAK.
    OrthoDBiEOG7992R9.
    PhylomeDBiQ9Y271.
    TreeFamiTF350009.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR013310. CLT1_recept.
    IPR004071. Cyst_leuk_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR01902. CYSLT1RECPTR.
    PR01533. CYSLTRECPTR.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Y271-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDETGNLTVS SATCHDTIDD FRNQVYSTLY SMISVVGFFG NGFVLYVLIK    50
    TYHKKSAFQV YMINLAVADL LCVCTLPLRV VYYVHKGIWL FGDFLCRLST 100
    YALYVNLYCS IFFMTAMSFF RCIAIVFPVQ NINLVTQKKA RFVCVGIWIF 150
    VILTSSPFLM AKPQKDEKNN TKCFEPPQDN QTKNHVLVLH YVSLFVGFII 200
    PFVIIIVCYT MIILTLLKKS MKKNLSSHKK AIGMIMVVTA AFLVSFMPYH 250
    IQRTIHLHFL HNETKPCDSV LRMQKSVVIT LSLAASNCCF DPLLYFFSGG 300
    NFRKRLSTFR KHSLSSVTYV PRKKASLPEK GEEICKV 337
    Length:337
    Mass (Da):38,541
    Last modified:November 1, 1999 - v1
    Checksum:iB9B53940F895F245
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti272 – 2721R → T in AAH35750. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF119711 mRNA. Translation: AAD42285.1.
    AF133266 mRNA. Translation: AAD42778.1.
    AY242130 Genomic DNA. Translation: AAO92297.1.
    AK313643 mRNA. Translation: BAG36401.1.
    AL445202 Genomic DNA. Translation: CAI40462.1.
    CH471104 Genomic DNA. Translation: EAW98598.1.
    CH471104 Genomic DNA. Translation: EAW98599.1.
    BC035750 mRNA. Translation: AAH35750.1.
    CCDSiCCDS14439.1.
    RefSeqiNP_001269115.1. NM_001282186.1.
    NP_001269116.1. NM_001282187.1.
    NP_001269117.1. NM_001282188.1.
    NP_006630.1. NM_006639.3.
    UniGeneiHs.733809.

    Genome annotation databases

    EnsembliENST00000373304; ENSP00000362401; ENSG00000173198.
    GeneIDi10800.
    KEGGihsa:10800.
    UCSCiuc004edb.3. human.

    Polymorphism databases

    DMDMi20138087.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF119711 mRNA. Translation: AAD42285.1 .
    AF133266 mRNA. Translation: AAD42778.1 .
    AY242130 Genomic DNA. Translation: AAO92297.1 .
    AK313643 mRNA. Translation: BAG36401.1 .
    AL445202 Genomic DNA. Translation: CAI40462.1 .
    CH471104 Genomic DNA. Translation: EAW98598.1 .
    CH471104 Genomic DNA. Translation: EAW98599.1 .
    BC035750 mRNA. Translation: AAH35750.1 .
    CCDSi CCDS14439.1.
    RefSeqi NP_001269115.1. NM_001282186.1.
    NP_001269116.1. NM_001282187.1.
    NP_001269117.1. NM_001282188.1.
    NP_006630.1. NM_006639.3.
    UniGenei Hs.733809.

    3D structure databases

    ProteinModelPortali Q9Y271.
    SMRi Q9Y271. Positions 29-303.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q9Y271. 1 interaction.
    STRINGi 9606.ENSP00000362401.

    Chemistry

    BindingDBi Q9Y271.
    ChEMBLi CHEMBL2094254.
    DrugBanki DB01025. Amlexanox.
    DB00587. Cinalukast.
    DB00471. Montelukast.
    DB00716. Nedocromil.
    DB01411. Pranlukast.
    DB00549. Zafirlukast.
    GuidetoPHARMACOLOGYi 269.

    Protein family/group databases

    TCDBi 9.A.14.13.2. the g-protein-coupled receptor (gpcr) family.
    GPCRDBi Search...

    PTM databases

    PhosphoSitei Q9Y271.

    Polymorphism databases

    DMDMi 20138087.

    Proteomic databases

    PaxDbi Q9Y271.
    PRIDEi Q9Y271.

    Protocols and materials databases

    DNASUi 10800.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000373304 ; ENSP00000362401 ; ENSG00000173198 .
    GeneIDi 10800.
    KEGGi hsa:10800.
    UCSCi uc004edb.3. human.

    Organism-specific databases

    CTDi 10800.
    GeneCardsi GC0XM077526.
    HGNCi HGNC:17451. CYSLTR1.
    HPAi HPA010546.
    MIMi 300201. gene.
    neXtProti NX_Q9Y271.
    PharmGKBi PA38453.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG119185.
    HOGENOMi HOG000236328.
    HOVERGENi HBG099611.
    InParanoidi Q9Y271.
    KOi K04322.
    OMAi PQDNQAK.
    OrthoDBi EOG7992R9.
    PhylomeDBi Q9Y271.
    TreeFami TF350009.

    Enzyme and pathway databases

    Reactomei REACT_18283. G alpha (q) signalling events.
    REACT_18302. Leukotriene receptors.

    Miscellaneous databases

    GeneWikii Cysteinyl_leukotriene_receptor_1.
    GenomeRNAii 10800.
    NextBioi 41017.
    PROi Q9Y271.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9Y271.
    Bgeei Q9Y271.
    CleanExi HS_CYSLTR1.
    Genevestigatori Q9Y271.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR013310. CLT1_recept.
    IPR004071. Cyst_leuk_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR01902. CYSLT1RECPTR.
    PR01533. CYSLTRECPTR.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Tonsil.
    2. "Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor."
      Sarau H.M., Ames R.S., Chambers J., Ellis C., Elshourbagy N., Foley J.J., Schmidt D.B., Muccitelli R.M., Jenkins O., Murdock P.R., Herrity N.C., Halsey W., Sathe G., Muir A.I., Nuthulaganti P., Dytko G.M., Buckley P.T., Wilson S., Bergsma D.J., Hay D.W.P.
      Mol. Pharmacol. 56:657-663(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Leukocyte, Peripheral blood monocyte and Spleen.
    3. "Isolation of complete coding sequence for cysteinyl leukotriene receptor 1 (CYSLTR1)."
      Warren C.N., Aronstam R.S., Sharma S.V.
      Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Uterus.
    5. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Pancreas.

    Entry informationi

    Entry nameiCLTR1_HUMAN
    AccessioniPrimary (citable) accession number: Q9Y271
    Secondary accession number(s): B2R954
    , D3DTE4, Q5JS94, Q8IV19
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 11, 2002
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 119 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    Selective antagonists, such as montelukast (Singulair), zafirlukast (Accolate) and pranlukast (Onon), are used in the treatment of the asthma crisis.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    3. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3