Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dehydrogenase/reductase SDR family protein 7-like

Gene

CG7601

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative oxidoreductase.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei193SubstrateSequence analysis1
Active sitei206Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi57 – 81NAD or NADPBy similarityAdd BLAST25

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD, NADP

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydrogenase/reductase SDR family protein 7-like (EC:1.1.-.-)
Gene namesi
ORF Names:CG7601
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0027583. CG7601.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 17CytoplasmicSequence analysisAdd BLAST17
Transmembranei18 – 38Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini39 – 326PeroxisomalSequence analysisAdd BLAST288

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003121131 – 326Dehydrogenase/reductase SDR family protein 7-likeAdd BLAST326

Proteomic databases

PaxDbiQ9Y140.
PRIDEiQ9Y140.

Expressioni

Gene expression databases

BgeeiFBgn0027583.
GenevisibleiQ9Y140. DM.

Interactioni

Protein-protein interaction databases

BioGridi68366. 4 interactors.
STRINGi7227.FBpp0084910.

Structurei

3D structure databases

ProteinModelPortaliQ9Y140.
SMRiQ9Y140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1205. Eukaryota.
COG1028. LUCA.
GeneTreeiENSGT00860000133667.
InParanoidiQ9Y140.
KOiK11166.
OMAiRYGVMDT.
OrthoDBiEOG091G0BO9.
PhylomeDBiQ9Y140.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Y140-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVQDMDKCA PSSDWNVLYW VLGTVLMPVA LPLAIINIWQ RFQAQKFRNQ
60 70 80 90 100
LPGKVVLITG ASSGLGESLA HVFYRAGCRV ILAARRTQEL ERVKKDLLAL
110 120 130 140 150
DVDPAYPPTV LPLDLAELNS IPEFVTRVLA VYNQVDILIN NGGISVRADV
160 170 180 190 200
ASTAVDVDLK VMVVNYFGSV ALTKALLPSM VKRGSGHICF ISSVQGKFAI
210 220 230 240 250
PQRAAYSASK HAMQAFADSL RAEVANKNIN VSCVSPGYIR TQLSLNALTG
260 270 280 290 300
SGSSYGKVDE TTAKGMSPDK LAERILQCIL RKEPDIIVSD VQAKIAYYLR
310 320
HLCPSLYFWI MAKRAVKLEN AEKKST
Length:326
Mass (Da):35,744
Last modified:November 1, 1999 - v1
Checksum:i0A70A38F2AB2BD6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56927.1.
AF145631 mRNA. Translation: AAD38606.1.
RefSeqiNP_651717.1. NM_143460.4.
UniGeneiDm.3158.

Genome annotation databases

EnsemblMetazoaiFBtr0085544; FBpp0084910; FBgn0027583.
GeneIDi43502.
KEGGidme:Dmel_CG7601.
UCSCiCG7601-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56927.1.
AF145631 mRNA. Translation: AAD38606.1.
RefSeqiNP_651717.1. NM_143460.4.
UniGeneiDm.3158.

3D structure databases

ProteinModelPortaliQ9Y140.
SMRiQ9Y140.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi68366. 4 interactors.
STRINGi7227.FBpp0084910.

Proteomic databases

PaxDbiQ9Y140.
PRIDEiQ9Y140.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0085544; FBpp0084910; FBgn0027583.
GeneIDi43502.
KEGGidme:Dmel_CG7601.
UCSCiCG7601-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0027583. CG7601.

Phylogenomic databases

eggNOGiKOG1205. Eukaryota.
COG1028. LUCA.
GeneTreeiENSGT00860000133667.
InParanoidiQ9Y140.
KOiK11166.
OMAiRYGVMDT.
OrthoDBiEOG091G0BO9.
PhylomeDBiQ9Y140.

Miscellaneous databases

GenomeRNAii43502.
PROiQ9Y140.

Gene expression databases

BgeeiFBgn0027583.
GenevisibleiQ9Y140. DM.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDHRS7_DROME
AccessioniPrimary (citable) accession number: Q9Y140
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: November 1, 1999
Last modified: November 30, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.