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Protein

Dehydrogenase/reductase SDR family protein 7-like

Gene

CG7601

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative oxidoreductase.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei193SubstrateSequence analysis1
Active sitei206Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi57 – 81NAD or NADPBy similarityAdd BLAST25

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD, NADP

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydrogenase/reductase SDR family protein 7-like (EC:1.1.-.-)
Gene namesi
ORF Names:CG7601
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0027583. CG7601.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 17CytoplasmicSequence analysisAdd BLAST17
Transmembranei18 – 38Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini39 – 326PeroxisomalSequence analysisAdd BLAST288

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003121131 – 326Dehydrogenase/reductase SDR family protein 7-likeAdd BLAST326

Proteomic databases

PaxDbiQ9Y140.
PRIDEiQ9Y140.

Expressioni

Gene expression databases

BgeeiFBgn0027583.
GenevisibleiQ9Y140. DM.

Interactioni

Protein-protein interaction databases

BioGridi68366. 4 interactors.
STRINGi7227.FBpp0084910.

Structurei

3D structure databases

ProteinModelPortaliQ9Y140.
SMRiQ9Y140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1205. Eukaryota.
COG1028. LUCA.
GeneTreeiENSGT00890000139353.
InParanoidiQ9Y140.
KOiK11166.
OMAiSMIKRRQ.
OrthoDBiEOG091G0BO9.
PhylomeDBiQ9Y140.

Family and domain databases

InterProiView protein in InterPro
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
PfamiView protein in Pfam
PF00106. adh_short. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00061. ADH_SHORT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Y140-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVQDMDKCA PSSDWNVLYW VLGTVLMPVA LPLAIINIWQ RFQAQKFRNQ
60 70 80 90 100
LPGKVVLITG ASSGLGESLA HVFYRAGCRV ILAARRTQEL ERVKKDLLAL
110 120 130 140 150
DVDPAYPPTV LPLDLAELNS IPEFVTRVLA VYNQVDILIN NGGISVRADV
160 170 180 190 200
ASTAVDVDLK VMVVNYFGSV ALTKALLPSM VKRGSGHICF ISSVQGKFAI
210 220 230 240 250
PQRAAYSASK HAMQAFADSL RAEVANKNIN VSCVSPGYIR TQLSLNALTG
260 270 280 290 300
SGSSYGKVDE TTAKGMSPDK LAERILQCIL RKEPDIIVSD VQAKIAYYLR
310 320
HLCPSLYFWI MAKRAVKLEN AEKKST
Length:326
Mass (Da):35,744
Last modified:November 1, 1999 - v1
Checksum:i0A70A38F2AB2BD6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF56927.1.
AF145631 mRNA. Translation: AAD38606.1.
RefSeqiNP_651717.1. NM_143460.4.
UniGeneiDm.3158.

Genome annotation databases

EnsemblMetazoaiFBtr0085544; FBpp0084910; FBgn0027583.
GeneIDi43502.
KEGGidme:Dmel_CG7601.
UCSCiCG7601-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiDHRS7_DROME
AccessioniPrimary (citable) accession number: Q9Y140
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families