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Protein
Submitted name:

BcDNA.GH08312

Gene

Sap-r

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • dsRNA transport Source: FlyBase
  • sphingolipid metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DME-114608. Platelet degranulation.
R-DME-1660662. Glycosphingolipid metabolism.
R-DME-375276. Peptide ligand-binding receptors.
R-DME-5683826. Surfactant metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
BcDNA.GH08312Imported
Submitted name:
Saposin-related proteinImported
Submitted name:
Saposin-related, isoform AImported
Gene namesi
Name:Sap-rImported
Synonyms:BcDNA.GH08312Imported
ORF Names:CG12070Imported, Dmel_CG12070Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0000416. Sap-r.

Subcellular locationi

GO - Cellular componenti

  • fusome Source: FlyBase
  • lysosome Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 953933Sequence analysisPRO_5007719209Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiFBgn0000416.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-875808.
STRINGi7227.FBpp0085075.

Structurei

3D structure databases

SMRiQ9Y125. Positions 72-148, 437-581.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 6441Saposin A-typeInterPro annotationAdd
BLAST
Domaini68 – 15083Saposin B-typeInterPro annotationAdd
BLAST
Domaini184 – 26380Saposin B-typeInterPro annotationAdd
BLAST
Domaini283 – 36381Saposin B-typeInterPro annotationAdd
BLAST
Domaini433 – 51482Saposin B-typeInterPro annotationAdd
BLAST
Domaini533 – 61482Saposin B-typeInterPro annotationAdd
BLAST
Domaini662 – 74382Saposin B-typeInterPro annotationAdd
BLAST
Domaini773 – 85381Saposin B-typeInterPro annotationAdd
BLAST
Domaini857 – 94286Saposin B-typeInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
GeneTreeiENSGT00530000063434.
KOiK12382.
OMAiDNKSKDN.
OrthoDBiEOG091G0K86.
PhylomeDBiQ9Y125.

Family and domain databases

Gene3Di1.10.225.10. 8 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 1 hit.
PF05184. SapB_1. 6 hits.
PF03489. SapB_2. 7 hits.
[Graphical view]
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 1 hit.
SM00741. SapB. 8 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 8 hits.
PROSITEiPS51110. SAP_A. 1 hit.
PS50015. SAP_B. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Y125-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAGLLAVL ALCCAFGVFA AATPLLGSSK CTWGPSYWCG NFSNSKECRA
60 70 80 90 100
TRHCIQTVWE TQKVPVDTDS ICTICKDMVT QARDQLKSNQ TEEELKEVFE
110 120 130 140 150
GSCKLIPIKP IQKECIKVAD DFLPELVEAL ASQMNPDQVC SVAGLCNSAR
160 170 180 190 200
IDELYKNGIQ AGLDGTVQNE DDSSEETELA MQPNQLSCGN CNLLSRLMHS
210 220 230 240 250
KFAATDRDDM VETMLHMCGS LSSFSDACAN IVLTYFNDIY DHVSKHLTTD
260 270 280 290 300
AVCHVSGVCA SRYHQHEEEK QPQEALVALD AGDDIPCELC EQLVKHLRDV
310 320 330 340 350
LVANTTETEF KQVMEGFCKQ SKGFKDECLS IVDQYYHVIY ETLVSKLDAN
360 370 380 390 400
GACCMIGICQ KNSASSMKDV PIMPLLPVIE PAQVKITIEK LEKHEKKQLG
410 420 430 440 450
ASEPKFSQQE ILDMQLPIDH LMGAANPGAL VEGGELCTLC EYMLHFIQET
460 470 480 490 500
LATPSTDDEI KHTVENICAK LPSGVAGQCR NFVEMYGDAV IALLVQGLNP
510 520 530 540 550
RDVCPLMQMC PKNLPKKEDV EVFNPQPASD EQDPPTCPLC LFAVEQAQMK
560 570 580 590 600
IRDNKSKDNI KKVLNGLCSH LPNEIKEECV DFVNTYSNEL IDMLITDFKP
610 620 630 640 650
QEICVQLKLC PKTTYALWDL RISLEDDVDG EDKSSSEEIS FNDIESLEEL
660 670 680 690 700
PPQLAFDPGF TAAPNCLICE ELVKTLEKRM GKHPTRDSIK HILEESCDRM
710 720 730 740 750
RKPMNTKCHK VIDKYGDKIA DLLLKEMDPK LICTELGMCI LADLDDLEVD
760 770 780 790 800
EALKYDVIAL PRQDNKLSSS IKEPPTCVLC EFIMTKLDAD LKNKTEQDDI
810 820 830 840 850
KRAIEAVCNR LPATVRKQCD TFVDGYASAV LKLLSDVPPK QVCQKLQLCF
860 870 880 890 900
SVAVTDEVLE CGVCHGVTQA LLPFLREKKD NVSEVTALQM TSVGCENLPA
910 920 930 940 950
KYYKICSEMI SIYGSSIKNL AKRPYIDQSH ICAEIGKCFE SEKSSLAFAR

ISA
Length:953
Mass (Da):105,963
Last modified:November 1, 1999 - v1
Checksum:iD6CFFD3E9D1502A8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei953 – 9531Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF145647 mRNA. Translation: AAD38622.1.
AE014297 Genomic DNA. Translation: AAF57097.1.
DQ062780 mRNA. Translation: AAY56653.1.
RefSeqiNP_524597.1. NM_079858.4.
UniGeneiDm.7825.

Genome annotation databases

EnsemblMetazoaiFBtr0085713; FBpp0085075; FBgn0000416.
GeneIDi43662.
KEGGidme:Dmel_CG12070.
UCSCiCG12070-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF145647 mRNA. Translation: AAD38622.1.
AE014297 Genomic DNA. Translation: AAF57097.1.
DQ062780 mRNA. Translation: AAY56653.1.
RefSeqiNP_524597.1. NM_079858.4.
UniGeneiDm.7825.

3D structure databases

SMRiQ9Y125. Positions 72-148, 437-581.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-875808.
STRINGi7227.FBpp0085075.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0085713; FBpp0085075; FBgn0000416.
GeneIDi43662.
KEGGidme:Dmel_CG12070.
UCSCiCG12070-RA. d. melanogaster.

Organism-specific databases

CTDi43662.
FlyBaseiFBgn0000416. Sap-r.

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
GeneTreeiENSGT00530000063434.
KOiK12382.
OMAiDNKSKDN.
OrthoDBiEOG091G0K86.
PhylomeDBiQ9Y125.

Enzyme and pathway databases

ReactomeiR-DME-114608. Platelet degranulation.
R-DME-1660662. Glycosphingolipid metabolism.
R-DME-375276. Peptide ligand-binding receptors.
R-DME-5683826. Surfactant metabolism.

Miscellaneous databases

GenomeRNAii43662.

Gene expression databases

BgeeiFBgn0000416.

Family and domain databases

Gene3Di1.10.225.10. 8 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 1 hit.
PF05184. SapB_1. 6 hits.
PF03489. SapB_2. 7 hits.
[Graphical view]
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 1 hit.
SM00741. SapB. 8 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 8 hits.
PROSITEiPS51110. SAP_A. 1 hit.
PS50015. SAP_B. 8 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9Y125_DROME
AccessioniPrimary (citable) accession number: Q9Y125
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: September 7, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.