Unreviewed, UniProtKB/TrEMBL Q9XYQ9 (Q9XYQ9_DROME)

Names and origin

Protein names

Submitted name:
    TNF-receptor-associated factor 2 EMBL AAD34345.1

Gene names

Name:	Traf6 FlyBase FBgn0026318
Synonyms:	TRAF2 EMBL AAD34345.1, Traf2 FlyBase FBgn0026318
ORF Names:	CG10961 FlyBase FBgn0026318

Organism

Drosophila melanogaster (Fruit fly) EMBL AAD34345.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Domain	Zinc-finger RuleBase RU000353V2
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	Toll signaling pathway Traceable author statement. Source: FlyBase dorsal closure Traceable author statement. Source: FlyBase innate immune response Inferred from mutant phenotype. Source: FlyBase regulation of I-kappaB kinase/NF-kappaB cascade Inferred from mutant phenotype. Source: FlyBase
Cellular component	intracellular Traceable author statement. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: IntAct receptor activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
wgn	Q9VWS4	1	EBI-499715,EBI-161953

Sequences

	Sequence		Length	Mass (Da)
	Q9XYQ9-1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: D4F23B9EECD78145	FASTA	463	52,426
	10 20 30 40 50 60 MHQHAHTHSH AHSLQHAEEK EHNSNEMTTN LSSTGRIAAS SSATPSAAAG GGASGAPTPP 70 80 90 100 110 120 KSLALNQNHH YAPGSDTSGE QEEELLDSRY ECAICIDWLN EPVLTSCGHR FCRSCLTAWM 130 140 150 160 170 180 QKNNQCWPMD NKRLSAEHDI FPDNYTRREI EQLKRDCPNS SLGCSVVASP IELHRHLPSC 190 200 210 220 230 240 PYRRQQEPQE EKCPFAKIKC DFVGRPETNQ LEEHLKADMP HHMQLMLQAF QQTAIATWQP 250 260 270 280 290 300 HKPSTSGAAV ENGHGQQQLP PPPPYANGVD EQIVQTMYQR IVVLEQRTRE QETRLENMQK 310 320 330 340 350 360 QLRLARQQAP VDPRYSNGTI VWRIEQLGAL VARLRANANN QVYSHECYTS PHGYKFCARL 370 380 390 400 410 420 TFSRGKPHVL SLHVHLMQSE NDYHLDWPFK GRIKLCMVHP ADATLSQHDT IMTKPEILAF 430 440 450 460 HKPREAISTR GFGFLEYANI SNIIQLGFCA DDRLLIKIEI NIV

References

[1]	"A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase." Liu H., Su Y.C., Becker E., Treisman J., Skolnik E.Y. Curr. Biol. 9:101-104(1999) [PubMed: 10021364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Skolnik E.S., Liu H., Su Y.-C., Becker E., Treisman J. Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF119793 mRNA. Translation: AAD34345.1.
3D structure databases
HSSP	HSSP built from PDB template 1LB4 based on UniProtKB Q9Y4K3.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9XYQ9. 2 interactions.
Proteomic databases
PRIDE	Q9XYQ9.
Genome annotation databases
Ensembl	FBgn0026318. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0026318. Traf6.
Gene expression databases
ArrayExpress	Q9XYQ9.
Family and domain databases
InterPro	IPR002083. MATH. IPR013322. TRAF-type. IPR018957. Znf_C3HC4_RING-type. IPR001841. Znf_RING. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:2.60.210.10. TRAF-type. 1 hit.
Pfam	PF00097. zf-C3HC4. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. [Graphical view]
PROSITE	PS50144. MATH. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9XYQ9_DROME

Accession

Primary (citable) accession number: Q9XYQ9

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	June 16, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)