Q9XYQ9 (Q9XYQ9_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
TNF-receptor-associated factor 2 EMBL AAD34345.1

Gene names

Name:	Traf6 FlyBase FBgn0026318
Synonyms:	Traf2 FlyBase FBgn0026318, TRAF2 EMBL AAD34345.1
ORF Names:	CG10961 FlyBase FBgn0026318

Organism

Drosophila melanogaster (Fruit fly) EMBL AAD34345.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 MATH domain. RuleBase RU004402 Contains 1 RING-type zinc finger. SAAS SAAS013323

Ontologies

Keywords
Domain	Zinc-finger RuleBase RU000353 SAAS SAAS013323
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	Toll signaling pathway Traceable author statement. Source: FlyBase cell death Inferred from genetic interaction. Source: FlyBase dorsal closure Traceable author statement. Source: FlyBase innate immune response Inferred from mutant phenotype. Source: FlyBase regulation of I-kappaB kinase/NF-kappaB cascade Inferred from mutant phenotype. Source: FlyBase stress-activated protein kinase signaling cascade Inferred from mutant phenotype. Source: FlyBase
Cellular component	intracellular Traceable author statement. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: FlyBase ubiquitin-protein ligase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9XYQ9 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: D4F23B9EECD78145	FASTA	463	52,426
	10 20 30 40 50 60 MHQHAHTHSH AHSLQHAEEK EHNSNEMTTN LSSTGRIAAS SSATPSAAAG GGASGAPTPP 70 80 90 100 110 120 KSLALNQNHH YAPGSDTSGE QEEELLDSRY ECAICIDWLN EPVLTSCGHR FCRSCLTAWM 130 140 150 160 170 180 QKNNQCWPMD NKRLSAEHDI FPDNYTRREI EQLKRDCPNS SLGCSVVASP IELHRHLPSC 190 200 210 220 230 240 PYRRQQEPQE EKCPFAKIKC DFVGRPETNQ LEEHLKADMP HHMQLMLQAF QQTAIATWQP 250 260 270 280 290 300 HKPSTSGAAV ENGHGQQQLP PPPPYANGVD EQIVQTMYQR IVVLEQRTRE QETRLENMQK 310 320 330 340 350 360 QLRLARQQAP VDPRYSNGTI VWRIEQLGAL VARLRANANN QVYSHECYTS PHGYKFCARL 370 380 390 400 410 420 TFSRGKPHVL SLHVHLMQSE NDYHLDWPFK GRIKLCMVHP ADATLSQHDT IMTKPEILAF 430 440 450 460 HKPREAISTR GFGFLEYANI SNIIQLGFCA DDRLLIKIEI NIV

References

[1]	"A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase." Liu H., Su Y.C., Becker E., Treisman J., Skolnik E.Y. Curr. Biol. 9:101-104(1999) [PubMed: 10021364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Skolnik E.S., Liu H., Su Y.-C., Becker E., Treisman J. Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF119793 mRNA. Translation: AAD34345.1.
3D structure databases
HSSP	HSSP built from PDB template 1LB4 based on UniProtKB Q9Y4K3.
ProteinModelPortal	Q9XYQ9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9XYQ9. 1 interaction.
STRING	Q9XYQ9.
Proteomic databases
PRIDE	Q9XYQ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0026318. Traf6.
Phylogenomic databases
GeneTree	EMGT00050000009274.
InParanoid	Q9XYQ9.
Gene expression databases
ArrayExpress	Q9XYQ9.
Bgee	Q9XYQ9.
Family and domain databases
InterPro	IPR002083. MATH. IPR013323. SIAH-type. IPR008974. TRAF-like. IPR013322. TRAF-type. IPR018957. Znf_C3HC4_RING-type. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:3.90.890.10. SIAH-type. 1 hit. G3DSA:2.60.210.10. TRAF-type. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
Pfam	PF00917. MATH. 1 hit. PF00097. zf-C3HC4. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF49599. Traf_like. 2 hits.
PROSITE	PS50144. MATH. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9XYQ9_DROME

Accession

Primary (citable) accession number: Q9XYQ9

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	November 16, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)